Biological Research for Nursing

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Perceived Racial Discrimination and DNA Methylation Among African American Women in the InterGEN Study
Biological Research for Nursing - Tập 20 Số 2 - Trang 145-152 - 2018
Veronica Barcelona, Yunfeng Huang, Cindy A. Crusto, Yan V. Sun, Jacquelyn Y. Taylor
Introduction: Experiences of racial discrimination have been associated with poor health outcomes. Little is known, however, about how perceived racial discrimination influences DNA methylation (DNAm) among African Americans (AAs). We examined the association of experiences of discrimination with DNAm among AA women in the Intergenerational Impact of Gene...... hiện toàn bộ
Sleep Patterns and Fatigue in New Mothers and Fathers
Biological Research for Nursing - Tập 5 Số 4 - Trang 311-318 - 2004
Caryl L. Gay, Kathryn A. Lee, Shih‐Yu Lee
The purpose of this study was to describe the sleep patterns and fatigue of both mothers and fathers before and after childbirth. The authors used wrist actigraphy and questionnaires to estimate sleep and fatigue in 72 couples during their last month of pregnancy and 1st month postpartum. Both parents experienced more sleep disruption at night during the postpartum period as compared to t...... hiện toàn bộ
Characterization of Spatial Learning and Sickness Responses in Aging Rats Following Recurrent Lipopolysaccharide Administration
Biological Research for Nursing - Tập 22 Số 1 - Trang 92-102 - 2020
Barbara J. Kupferschmid, Pamela Johnson Rowsey, Michael Riviera
Infections in older individuals can result in cognitive function decline, yet research is limited on how recurrent infections affect cognitive responses. Activation of the immune system results in sickness responses mediated by cytokines. This pilot study examined effects of a model of recurrent infection in aged, male Brown Norway rats on sickness responses, including spatial learning, a...... hiện toàn bộ
Spatial Learning Responses to Lipopolysaccharide in Adult and Aged Rats
Biological Research for Nursing - Tập 20 Số 1 - Trang 32-39 - 2018
Barbara J. Kupferschmid, Barbara Therrien
Sickness behaviors, adaptive responses to infections, include lethargy, depression, reduced eating and grooming, and concentration problems resulting from interactions between the immune and neuroendocrine systems. Detecting these responses is especially critical in the elderly, as the infections that cause them can lead to cognitive impairment. While deficits in spatial learning, a hippo...... hiện toàn bộ
Serum Tryptophan Metabolite Levels During Sleep in Patients With and Without Irritable Bowel Syndrome (IBS)
Biological Research for Nursing - Tập 18 Số 2 - Trang 193-198 - 2016
Margaret Heitkemper, Claire J. Han, Monica Jarrett, Haiwei Gu, Danijel Djukovic, Robert J. Shulman, Daniel Raftery, Wendy A. Henderson, Kevin C. Cain
Poor sleep and stress are more frequently reported by women with irritable bowel syndrome (IBS) than by healthy control (HC) women. The pathophysiology linking poor sleep and stress to gastrointestinal symptoms remains poorly understood. We used a metabolomic approach to determine whether tryptophan (TRP) metabolites differ between women with and without IBS and whether the levels are ass...... hiện toàn bộ
Cognitive Executive Dysfunction in Children with Mild Sleep-Disordered Breathing
Biological Research for Nursing - Tập 5 Số 3 - Trang 168-176 - 2004
Kristen Hedger Archbold, Bruno Giordani, Deborah L. Ruzicka, Ronald D. Chervin
In children, moderate or severe sleep-disordered breathing (SDB) may impair cognitive executive functions (EFs), including working memory, attention, and mental flexibility. The main objective of this study was to assess EFs in children with mild levels of SDB. Subjects for this descriptive study were 12 children (5 girls, 7 boys) aged 8.0 to 11.9 years (M = 9.0 ± 0.85) participating in a...... hiện toàn bộ
Circulating Cell-Free DNA Differentiates Severity of Inflammation
Biological Research for Nursing - Tập 18 Số 5 - Trang 477-488 - 2016
Mayu O. Frank
Introduction: As the U.S. population ages, the incidence of chronic disease will rise. Chronic diseases have been linked to chronic inflammation. The purpose of this review is to summarize the literature on cell-free DNA (cfDNA) in relation to inflammation. Methods: PubMed, EMBASE, and Web of ...... hiện toàn bộ
Measuring Stress in Young Children Using Hair Cortisol: The State of the Science
Biological Research for Nursing - Tập 19 Số 5 - Trang 499-510 - 2017
Randi A. Bates, Pamela J. Salsberry, Jodi L. Ford
Extensive literature suggests that adverse experiences in early childhood may deleteriously impact later health. These effects are thought to be related to the impact of persistent or chronic stress on various biological processes, mediated by dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis, and ultimately irregularities in cortisol levels. Ameliorating persistent stress in ...... hiện toàn bộ
Wound Bioburden and Infection-Related Complications in Diabetic Foot Ulcers
Biological Research for Nursing - Tập 10 Số 1 - Trang 44-53 - 2008
Sue E. Gardner, Rita A. Frantz
The identification and diagnosis of diabetic foot ulcer (DFU) infections remains a complex problem. Because inflammatory responses to microbial invasion may be diminished in persons with diabetes, clinical signs of infection are often absent in persons with DFUs when infection is limited to localized tissue. In the absence of these clinical signs, microbial load is believed to be the best...... hiện toàn bộ
Serum Prolactin in Breastfeeding: State of the Science
Biological Research for Nursing - Tập 1 Số 1 - Trang 65-75 - 1999
Pamela D. Hill, Robert T. Chatterton, Jean C. Aldag
Prolactin is one of two major hormones involved in lactation. While the role of infant suckling and oxytocin in the lactation process are well understood, the role of prolactin is less clear. A variety of factors related to prolactin have been investigated, and these are used as an organizing framework for this article. Factors include pregnancy, lactation, nursing frequency, prior lactati...... hiện toàn bộ
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