Biological Chemistry
SCOPUS (1881,1952,1975,1996-2023)SCIE-ISI
1431-6730
1437-4315
Đức
Cơ quản chủ quản: Walter de Gruyter GmbH
Lĩnh vực:
Molecular BiologyClinical BiochemistryBiochemistry
Phân tích ảnh hưởng
Các bài báo tiêu biểu
Glutathione dysregulation and the etiology and progression of human diseasesAbstract Glutathione (GSH) plays an important role in a multitude of cellular processes, including cell differentiation, proliferation, and apoptosis, and as a result, disturbances in GSH homeostasis are implicated in the etiology and/or progression of a number of human diseases, including cancer, diseases of aging, cystic fibrosis, and cardiovascular, inflammatory,... ...
Tập 390 Số 3 - Trang 191-214 - 2009
Mitophagy: mechanisms, pathophysiological roles, and analysisAbstract
Mitochondria are essential organelles that regulate cellular energy homeostasis and cell death. The removal of damaged mitochondria through autophagy, a process called mitophagy, is thus critical for maintaining proper cellular functions. Indeed, mitophagy has been recently proposed to play critical roles in terminal differentiation of red b... ...
Tập 393 Số 7 - Trang 547-564 - 2012
The role of oxidative stress during inflammatory processesAbstract The production of various reactive oxidant species in excess of endogenous antioxidant defense mechanisms promotes the development of a state of oxidative stress, with significant biological consequences. In recent years, evidence has emerged that oxidative stress plays a crucial role in the development and perpetuation of inflammation, and thus contributes... ...
Tập 395 Số 2 - Trang 203-230 - 2014
The coming of age of virus-like particle vaccinesAbstract
Virus-like particles are supra-molecular assemblages, usually icosahedral or rod-like structures. They incorporate key immunologic features of viruses which include repetitive surfaces, particulate structures and induction of innate immunity through activation of pathogen-associated molecular-pattern recognition receptors. They carry no repl... ...
Tập 389 Số 5 - Trang 521-536 - 2008
Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophyAbstract
Muscle loss during aging and disuse is a highly prevalent and disabling condition, but knowledge about cellular pathways mediating muscle atrophy is still limited. Given the postmitotic nature of skeletal myocytes, the maintenance of cellular homeostasis relies on the efficiency of cellular quality control mechanisms. In this scenario, alter... ...
Tập 394 Số 3 - Trang 393-414 - 2013
A Unique Cascade of Oxidoreductases Catalyses Trypanothione-Mediated Peroxide Metabolism in Crithidia fasciculata
Tập 378 Số 8 - 1997
An introduction to the molecular basics of aryl hydrocarbon receptor biologyAbstract Depending on their chemical structure and properties, environmental chemicals and other xenobiotics that enter the cell can affect cellular function by either nonselective binding to cellular macromolecules or by interference with cellular receptors, which would initiate a more defined cell biological response. One of these intracellular chemosensor molecul... ...
Tập 391 Số 11 - 2010
C-reactive protein and inflammation: conformational changes affect functionAbstract
The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as a useful marker and gauge of inflammation. CRP also plays an important role in host defense against invading pathogens as well as in inflammation. CRP consists of five identical subunits arranged as a cyclic pentamer. CRP exists in at least two conformationally distinc... ...
Tập 396 Số 11 - Trang 1181-1197 - 2015