BioMed Research International
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GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
BioMed Research International - Tập 2015 - Trang 1-7 - 2015
GHK (glycyl-L-histidyl-L-lysine) is present in human plasma, saliva, and urine
but declines with age. It is proposed that GHK functions as a complex with
copper 2+ which accelerates wound healing and skin repair. GHK stimulates both
synthesis and breakdown of collagen and glycosaminoglycans and modulates the
activity of both metalloproteinases and their inhibitors. It stimulates
collagen, dermatan...
The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes
BioMed Research International - Tập 2014 - Trang 1-8 - 2014
Cartilage extracellular matrix (ECM) is composed primarily of the network type
II collagen (COLII) and an interlocking mesh of fibrous proteins and
proteoglycans (PGs), hyaluronic acid (HA), and chondroitin sulfate (CS).
Articular cartilage ECM plays a crucial role in regulating chondrocyte
metabolism and functions, such as organized cytoskeleton through
integrin-mediated signaling via cell-matrix...
Evaluation of the Performance of Females as Light Infantry Soldiers
BioMed Research International - Tập 2014 - Trang 1-7 - 2014
A few countries permit women to serve in combat roles, but their long term
performance in these positions has not been reported. The incidences of overuse
injuries and attrition of 85 male and 235 female recruits in a light infantry
brigade was followed in a three-year prospective study. Females were shorter
(162 cm, CI 161–163 cm) than males (174 cm, CI 173–176), had more body fat
(18.9 kg, CI 18...
What Is Recent in Pancreatic Cancer Immunotherapy?
BioMed Research International - Tập 2013 - Trang 1-14 - 2013
Pancreatic cancer (PC) represents an unresolved therapeutic challenge, due to
the poor prognosis and the reduced response to currently available treatments.
Pancreatic cancer is the most lethal type of digestive cancers, with a median
survival of 4–6 months. Only a small proportion of PC patients is curative by
surgical resection, whilst standard chemotherapy for patients in advanced
disease gener...
Effects of Adult Male Circumcision on Premature Ejaculation: Results from a Prospective Study in China
BioMed Research International - Tập 2015 - Trang 1-7 - 2015
The purpose of this study is to investigate the effects of adult male
circumcision on premature ejaculation (PE). Therefore, between December 2009 and
March 2014, a total of 575 circumcised men and 623 uncircumcised men (control
group) were evaluated. Detailed evaluations (including circumcision and control
groups) on PE were conducted before circumcision and at the 3-, 6-, 9-, and
12-month follow...
MicroRNAs in Cancer Management: Big Challenges for Small Molecules
BioMed Research International - Tập 2015 - Trang 1-2 - 2015
On the Feasibility of Utilizing Allogeneic Bone Blocks for Atrophic Maxillary Augmentation
BioMed Research International - Tập 2014 - Trang 1-12 - 2014
Purpose. This systematic review was aimed at assessing the feasibility by means
of survival rate, histologic analysis, and causes of failure of allogeneic block
grafts for augmenting the atrophic maxilla.Material and Methods. A literature
search was conducted by one reviewer in several databases. Articles were
included in this systematic review if they were human clinical trials in which
outcomes ...
The Measurement of Maximal (Anaerobic) Power Output on a Cycle Ergometer: A Critical Review
BioMed Research International - Tập 2013 - Trang 1-40 - 2013
The interests and limits of the different methods and protocols of maximal
(anaerobic) power () assessment are reviewed: single all-out
testsversusforce-velocity tests, isokinetic ergometersversusfriction-loaded
ergometers, measure of during the acceleration phase or at peak velocity. The
effects of training, athletic practice, diet and pharmacological substances upon
the production of maximal mec...
Using the Sadakane Compressed Suffix Tree to Solve the All-Pairs Suffix-Prefix Problem
BioMed Research International - Tập 2014 - Trang 1-11 - 2014
The all-pairs suffix-prefix matching problem is a basic problem in string
processing. It has an application in the de novo genome assembly task, which is
one of the major bioinformatics problems. Due to the large size of the input
data, it is crucial to use fast and space efficient solutions. In this paper, we
present a space-economical solution to this problem using the generalized
Sadakane compr...
A Practical and Scalable Tool to Find Overlaps between Sequences
BioMed Research International - Tập 2015 - Trang 1-12 - 2015
The evolution of the next generation sequencing technology increases the demand
for efficient solutions, in terms of space and time, for several bioinformatics
problems. This paper presents a practical and easy-to-implement solution for one
of these problems, namely, the all-pairs suffix-prefix problem, using a compact
prefix tree. The paper demonstrates an efficient construction of this
time-effi...
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