BioMed Research International

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The ECM-Cell Interaction of Cartilage Extracellular Matrix on Chondrocytes
BioMed Research International - Tập 2014 - Trang 1-8 - 2014
Yue Gao, Shuyun Liu, Jingxiang Huang, Weimin Guo, Jifeng Chen, Li Zhang, Bin Zhao, Jiang Peng, Aiyuan Wang, Yu Wang, Wenjing Xu, Shibi Lu, Mei Yuan, Mingjie Wang
Cartilage extracellular matrix (ECM) is composed primarily of the network type II collagen (COLII) and an interlocking mesh of fibrous proteins and proteoglycans (PGs), hyaluronic acid (HA), and chondroitin sulfate (CS). Articular cartilage ECM plays a crucial role in regulating chondrocyte metabolism and functions, such as organized cytoskeleton through integrin-mediated signaling via cel...... hiện toàn bộ
What Is Recent in Pancreatic Cancer Immunotherapy?
BioMed Research International - Tập 2013 - Trang 1-14 - 2013
Elena Niccolai, Domenico Prisco, Mario Milco D’Elios, Amedeo Amedei
Pancreatic cancer (PC) represents an unresolved therapeutic challenge, due to the poor prognosis and the reduced response to currently available treatments. Pancreatic cancer is the most lethal type of digestive cancers, with a median survival of 4–6 months. Only a small proportion of PC patients is curative by surgical resection, whilst standard chemotherapy for patients in advanced disea...... hiện toàn bộ
MicroRNAs in Cancer Management: Big Challenges for Small Molecules
BioMed Research International - Tập 2015 - Trang 1-2 - 2015
Paolo Gandellini, Elisa Giovannetti, Francesco Nicassio
On the Feasibility of Utilizing Allogeneic Bone Blocks for Atrophic Maxillary Augmentation
BioMed Research International - Tập 2014 - Trang 1-12 - 2014
Alberto Monje, Michael A. Pikos, Hsun‐Liang Chan, Fernando Suárez, Jordi Gargallo‐Albiol, Federico Hernández‐Alfaro, Pablo Galindo‐Moreno, Hom‐Lay Wang
Purpose. This systematic review was aimed at assessing the feasibility by means of survival rate, histologic analysis, and causes of failure of allogeneic block grafts for augmenting the atrophic maxilla.Material and Methods. A literature search was conducted by one reviewer in several databases. Articles were included in this systemati...... hiện toàn bộ
A Practical and Scalable Tool to Find Overlaps between Sequences
BioMed Research International - Tập 2015 - Trang 1-12 - 2015
Maan Haj Rachid, Qutaibah M. Malluhi
The evolution of the next generation sequencing technology increases the demand for efficient solutions, in terms of space and time, for several bioinformatics problems. This paper presents a practical and easy-to-implement solution for one of these problems, namely, the all-pairs suffix-prefix problem, using a compact prefix tree. The paper demonstrates an efficient construction of this t...... hiện toàn bộ
Murine Models of Systemic Lupus Erythematosus
BioMed Research International - Tập 2011 Số 1 - 2011
Daniel J. Perry, Allison Sang, Yiming Yin, Ying-Yi Zheng, Laurence Morel
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder. The study of diverse mouse models of lupus has provided clues to the etiology of SLE. Spontaneous mouse models of lupus have led to identification of numerous susceptibility loci from which several candidate genes have emerged. Meanwhile, induced models of lupus have provided insight into the role of environmental ...... hiện toàn bộ
Microarray Analysis of Circular RNA Expression Profile Associated with 5-Fluorouracil-Based Chemoradiation Resistance in Colorectal Cancer Cells
BioMed Research International - Tập 2017 - Trang 1-8 - 2017
Wei Xiong, Yiqin Ai, Yun-Fen Li, Qing Ye, Zhengting Chen, Jiyong Qin, Qiu-Yan Liu, Hong Wang, Yunhe Ju, Wenhui Li, Yunfeng Li
Preoperative 5-fluorouracil- (5-FU-) based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, the effect of 5-FU-based chemoradiotherapy on CRC is limited due to the development of chemoradiation resistance (CRR), and the molecular mechanisms underlying this resistance are yet to be investigated. Recently, circular RNAs (circRNAs), which can fu...... hiện toàn bộ
Watermelon (Citrullus lanatus(Thunb.) Matsum. and Nakai) Juice Modulates Oxidative Damage Induced by Low Dose X-Ray in Mice
BioMed Research International - Tập 2014 - Trang 1-6 - 2014
Mohd Khairul Amran Mohammad, Muhamad Idham Mohamed, Ainul Mardhiyah Zakaria, Hairil Rashmizal Abdul Razak, Wan Mazlina Md Saad
Watermelon is a natural product that contains high level of antioxidants and may prevent oxidative damage in tissues due to free radical generation following an exposure to ionizing radiation. The present study aimed to investigate the radioprotective effects of watermelon (Citrullus lanatus(Thunb.) Matsum. and Nakai) juice against oxidative damage induced by low...... hiện toàn bộ
Influenza Vaccination among Underserved African-American Older Adults
BioMed Research International - Tập 2020 - Trang 1-9 - 2020
Mohsen Bazargan, Cheryl Wisseh, Edward Adinkrah, Hoorolnesa Ameli, Delia Santana, Sharon Cobb, Shervin Assari
Background. Racial disparities in influenza vaccination among underserved minority older adults are a public health problem. Understanding the factors that impact influenza vaccination behaviors among underserved older African-Americans could lead to more effective communication and delivery strategies. Aims. We aimed to investigate rate and factors associated with seasonal influenza vacci...... hiện toàn bộ
Epidemiology of Neonatal Sepsis and Implicated Pathogens: A Study from Egypt
BioMed Research International - Tập 2015 - Trang 1-11 - 2015
Eman M. Rabie Shehab El‐Din, Mohamed Mohamed Adel El‐Sokkary, Mohamed Reda Bassiouny, Ramadan Hassan
Prospective analytic study was conducted in NICUs of three Egyptian Neonatal Network (EGNN) participants in Mansoura Hospitals in Egypt over a period of 18 months from March 2011 to August 2012. By using EGNN 28-day discharge form, all demographic, clinical, and laboratory data were recorded and studied. During the study period, 357 neonates were diagnosed as suspected sepsis with an incid...... hiện toàn bộ
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