BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models - 2010
Chen Li, Marco Donizelli, Nicolás Rodríguez, Harish Dharuri, Lukas Endler, Vijayalakshmi Chelliah, Lu Li, Enuo He, Arnaud Henry, Melanie I. Stefan, Jacky L. Snoep, Michael Hucka, Nicolas Le Novère, Camille Laibe
Abstract
Background
Quantitative models of biochemical and cellular systems are used to answer a variety of questions in the biological sciences. The number of published quantitative models is growing steadily thanks to increasing interest in the use of models as well as the development of improv...... hiện toàn bộ
A review of imaging techniques for systems biology Tập 2 Số 1 - 2008
Armen R. Kherlopian, Ting Song, Qi Duan, Mathew A Neimark, Ming Jack Po, John K. Gohagan, Andrew F. Laine
Abstract
This paper presents a review of imaging techniques and of their utility in system biology. During the last decade systems biology has matured into a distinct field and imaging has been increasingly used to enable the interplay of experimental and theoretical biology. In this review, we describe and compare the roles of microscopy, ultrasound, CT ...... hiện toàn bộ
Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis Tập 1 Số 1 - 2007
Laxman Yetukuri, Mikko Katajamaa, Gema Medina-Gómez, Tuulikki Seppänen‐Laakso, Antonio Vidal‐Puig, Matej Orešič
Abstract
Background
Lipids are an important and highly diverse class of molecules having structural, energy storage and signaling roles. Modern analytical technologies afford screening of many lipid molecular species in parallel. One of the biggest challenges of lipidomics is elucidation of impor...... hiện toàn bộ
Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE - 2012
Yuliang Wang, James A. Eddy, Nathan D. Price
Abstract
Background
Human tissues perform diverse metabolic functions. Mapping out these tissue-specific functions in genome-scale models will advance our understanding of the metabolic basis of various physiological and pathological processes. The global knowledgebase of metabolic functions cate...... hiện toàn bộ
Extended local similarity analysis (eLSA) of microbial community and other time series data with replicates Tập 5 Số S2 - 2011
Xiaoling Zhang, Joshua A. Steele, Jacob A. Cram, Zoë G. Cardon, Stephanie Simmons, Joseph J. Vallino, Jed A. Fuhrman, Fengzhu Sun
Abstract
Background
The increasing availability of time series microbial community data from metagenomics and other molecular biological studies has enabled the analysis of large-scale microbial co-occurrence and association networks. Among the many analytical techniques available, the Local Simi...... hiện toàn bộ
Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance Tập 3 Số 1 - 2009
Özgür Şahin, Holger Fröhlich, Christian Löbke, Ulrike Korf, Sara Burmester, Meher Majety, Jens Mattern, Ingo Schupp, Claudine Chaouiya, Denis Thieffry, Annemarie Poustka, Stefan Wiemann, Tim Beißbarth, Dorit Arlt