BMC Medical Research Methodology

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What does a modified-Fibonacci dose-escalation actually correspond to?
BMC Medical Research Methodology - Tập 12 Số 1 - 2012
Nicolas Penel, Andrew Kramar
Thử nghiệm liều tăng dần giai đoạn I trong ung thư với nhiều lịch trình liên tiếp Dịch bởi AI
BMC Medical Research Methodology - Tập 21 - Trang 1-14 - 2021
Burak Kürsad Günhan, Sebastian Weber, Abdelkader Seroutou, Tim Friede
Các phương pháp thông thường cho các thử nghiệm liều tăng dần giai đoạn I trong ung thư chủ yếu dựa trên một lịch trình điều trị duy nhất. Tuy nhiên, gần đây, nhiều lịch trình đã được điều tra thường xuyên hơn trong cùng một thử nghiệm. Tại đây, chúng tôi xem xét các thử nghiệm giai đoạn I tuần tự, trong đó thử nghiệm tiếp tục với một lịch trình mới (ví dụ: liều hàng ngày hoặc hàng tuần) khi quá t...... hiện toàn bộ
A comparison of methods to estimate the survivor average causal effect in the presence of missing data: a simulation study
BMC Medical Research Methodology - Tập 19 - Trang 1-14 - 2019
Myra B. McGuinness, Jessica Kasza, Amalia Karahalios, Robyn H. Guymer, Robert P. Finger, Julie A. Simpson
Attrition due to death and non-attendance are common sources of bias in studies of age-related diseases. A simulation study is presented to compare two methods for estimating the survivor average causal effect (SACE) of a binary exposure (sex-specific dietary iron intake) on a binary outcome (age-related macular degeneration, AMD) in this setting. A dataset of 10,000 participants was simulated 120...... hiện toàn bộ
Applying an intersectionality lens to the theoretical domains framework: a tool for thinking about how intersecting social identities and structures of power influence behaviour
BMC Medical Research Methodology - Tập 20 - Trang 1-13 - 2020
Cole Etherington, Isabel Braganca Rodrigues, Lora Giangregorio, Ian D. Graham, Alison M. Hoens, Danielle Kasperavicius, Christine Kelly, Julia E. Moore, Matteo Ponzano, Justin Presseau, Kathryn M. Sibley, Sharon Straus
A key component of the implementation process is identifying potential barriers and facilitators that need to be addressed. The Theoretical Domains Framework (TDF) is one of the most commonly used frameworks for this purpose. When applying the TDF, it is critical to understand the context in which behaviours occur. Intersectionality, which accounts for the interface between social identity factors...... hiện toàn bộ
Applications of functional data analysis: A systematic review
BMC Medical Research Methodology - Tập 13 - Trang 1-12 - 2013
Shahid Ullah, Caroline F Finch
Functional data analysis (FDA) is increasingly being used to better analyze, model and predict time series data. Key aspects of FDA include the choice of smoothing technique, data reduction, adjustment for clustering, functional linear modeling and forecasting methods. A systematic review using 11 electronic databases was conducted to identify FDA application studies published in the peer-review l...... hiện toàn bộ
Adoption of workplaces and reach of employees for a multi-faceted intervention targeting low back pain among nurses’ aides
BMC Medical Research Methodology - - 2014
Charlotte Diana Nørregaard Rasmussen, Anne Konring Larsen, Andreas Holtermann, Karen Søgaard, Marie Birk Jørgensen
Methodological quality and reporting quality of COVID-19 living systematic review: a cross-sectional study
BMC Medical Research Methodology - Tập 23 - Trang 1-13 - 2023
Jiefeng Luo, Zhe Chen, Dan Liu, Hailong Li, Siyi He, Linan Zeng, Mengting Yang, Zheng Liu, Xue Xiao, Lingli Zhang
The main objective of this study is to evaluate the methodological quality and reporting quality of living systematic reviews (LSRs) on Coronavirus disease 2019 (COVID-19), while the secondary objective is to investigate potential factors that may influence the overall quality of COVID-19 LSRs. Six representative databases, including Medline, Excerpta Medica Database (Embase), Cochrane Library, C...... hiện toàn bộ
Can the buck always be passed to the highest level of clustering?
BMC Medical Research Methodology - - 2016
Christian Bottomley, Matthew J. Kirby, Steve W. Lindsay, Neal Alexander
Clustering commonly affects the uncertainty of parameter estimates in epidemiological studies. Cluster-robust variance estimates (CRVE) are used to construct confidence intervals that account for single-level clustering, and are easily implemented in standard software. When data are clustered at more than one level (e.g. village and household) the level for the CRVE must be chosen. CRVE are consis...... hiện toàn bộ
A data-driven approach to categorizing early life adversity exposure in the ABCD Study
BMC Medical Research Methodology - Tập 23 - Trang 1-12 - 2023
Natalia Orendain, Ariana Anderson, Adriana Galván, Susan Bookheimer, Paul J. Chung
Adversity occurring during development is associated with detrimental health and quality of life outcomes, not just following exposure but throughout the lifespan. Despite increased research, there exists both overlapping and distinct definitions of early life adversity exposure captured by over 30 different empirically validated tools. A data-driven approach to defining and cataloging exposure is...... hiện toàn bộ
Evaluation of the Total Design Method in a survey of Japanese dentists
BMC Medical Research Methodology - Tập 5 - Trang 1-9 - 2005
Yukie Nakai, Peter Milgrom, Toshiko Yoshida, Chikako Ishihara, Tsutomu Shimono
This study assessed the application of the Total Design Method (TDM) in a mail survey of Japanese dentists. The TDM was chosen because survey response rates in Japan are unacceptably low and the TDM had previously been used in a general population survey. Four hundred and seventy eight dentist members of the Okayama Medical and Dental Practitioner's Association were surveyed. The nine-page, 27-ite...... hiện toàn bộ
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