Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress Tập 13 Số 1 - 2013
Wei Qin, Xiaomei Ren, Yibo Jiang, Hong Jin, Naifeng Liu, Jie Li
Abstract Background Arterial media calcification (AMC) is highly prevalent and
is a major cause of morbidity, mortality, stroke and amputation in patients with
diabetes mellitus (DM). Previous research suggests that advanced glycation end
products (AGEs) are responsible for vascular calcification in diabetic patients.
The potential link between oxidative stress and AGEs-induced vascular
calcificat... hiện toàn bộ
Flow mediated dilation of the brachial artery: an investigation of methods requiring further standardization Tập 7 Số 1 - 2007
Alon Peretz, Daniel F. Leotta, Jeffrey Sullivan, Carol A. Trenga, Fiona N. Sands, M. Aulet, Marla Paun, Edward A. Gill, Joel D. Kaufman
Abstract Background In order to establish a consistent method for brachial
artery reactivity assessment, we analyzed commonly used approaches to the test
and their effects on the magnitude and time-course of flow mediated dilation
(FMD), and on test variability and repeatability. As a popular and noninvasive
assessment of endothelial function, several different approaches have been
employed to mea... hiện toàn bộ
Association of Gestational Diabetes Mellitus (GDM) with subclinical atherosclerosis: a systemic review and meta-analysis Tập 14 - Trang 1-9 - 2014
Jing-Wei Li, Si-Yi He, Peng Liu, Lin Luo, Liang Zhao, Ying-Bin Xiao
Gestational diabetes mellitus (GDM) is associated with an elevated risk of
adverse health outcomes such as type 2 diabetes and cardiovascular diseases.
Carotid intima-media thickness (cIMT) is increasingly used as a noninvasive
marker for subclinical atherosclerosis. Whether there is a direct correlation
between GDM and elevated cIMT is still controversial. PubMed, Embase and
reference lists of re... hiện toàn bộ
JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs Tập 5 Số 1 - 2005
Dimple Aggarwal, Kristy L. West, Tosca L. Zern, Smriti Shrestha, Marcela Vergara-Jiménez, María Luz Fernández
Abstract Background Microsomal transfer protein inhibitors (MTPi) have the
potential to be used as a drug to lower plasma lipids, mainly plasma
triglycerides (TG). However, studies with animal models have indicated that MTPi
treatment results in the accumulation of hepatic TG. The purpose of this study
was to evaluate whether JTT-130, a unique MTPi, targeted to the intestine, would
effectively red... hiện toàn bộ