Noninvasive detection of lung cancer by analysis of exhaled breath Tập 9 Số 1 - 2009
Amel Bajtarevic, Clemens Ager, Martin Pienz, Martin Klieber, Konrad Schwarz, Magdalena Ligor, Tomasz Ligor, Wojciech Filipiak, H. Denz, Michael Fiegl, Wolfgang Hilbe, Wolfgang Weiß, Peter Lukáš, Herbert Jamnig, Martin Hackl, Alfred Haidenberger, Bogusław Buszewski, Wolfram Miekisch, Jochen K. Schubert, Anton Amann
Abstract
Background
Lung cancer is one of the leading causes of death in Europe and the western world. At present, diagnosis of lung cancer very often happens late in the course of the disease since inexpensive, non-invasive and sufficiently sensitive and specific screening methods are not availa...... hiện toàn bộ The claudin gene family: expression in normal and neoplastic tissues Tập 6 Số 1 - 2006
Kyle J. Hewitt, Rachana Agarwal, Patrice J. Morin
AbstractBackgroundThe claudin (CLDN) genes encode a family of proteins important in tight junction formation and function. Recently, it has become apparent thatCLDNgene expression is frequently altered in several human cancers. However, the exact patterns ofCLDN... hiện toàn bộ Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression Tập 13 Số 1 - 2013
Kaihua Lu, Wei Li, Xianghua Li, Ming Sun, Meiling Zhang, Weiqin Wu, Weiping Xie, Yayi Hou
Abstract
Background
Long non-coding RNAs play an important role in tumorigenesis, hence, identification of cancer-associated lncRNAs and investigation of their biological functions and molecular mechanisms are important for understanding the development and progression of cancer. Recently, the do...... hiện toàn bộ Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment - 2011
Peter A. Fasching, Katharina Heusinger, Lothar Haeberle, Melitta Niklos, Alexander Hein, Christian Bayer, Claudia Rauh, R. Schulz-Wendtland, M. R. Bani, Michael G. Schrauder, Laura Kahmann, Michael P. Lux, Johanna Strehl, Arndt Hartmann, Arno Dimmler, Matthias W. Beckmann, David Wachter
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities - 2008
Joshua Z. Press, Alessandro De Luca, Niki Boyd, Sean Young, Armelle Troussard, Yolanda Ridge, Pardeep Kaurah, Steve E. Kalloger, Katherine A Blood, Margaret J. Smith, Paul T. Spellman, Yuker Wang, Dianne Miller, Doug Horsman, Malek Faham, C. Blake Gilks, Joe W. Gray, David G. Huntsman
Abstract
Background
Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis. Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as promoter hypermethylation can lead to decreased expression of BRCA1/2 in ovarian cancers....... hiện toàn bộ