BMC Cancer

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The bifunctional autophagic flux by 2-deoxyglucose to control survival or growth of prostate cancer cells
BMC Cancer - Tập 15 Số 1 - 2015
Jeong Yong Jeon, Seung Won Kim, Ki Cheong Park, Mijin Yun
Interference with Activator Protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells
BMC Cancer - Tập 10 - Trang 1-15 - 2010
Verena Thewes, Francesca Orso, Richard Jäger, Dawid Eckert, Sabine Schäfer, Gregor Kirfel, Stephan Garbe, Daniela Taverna, Hubert Schorle
Activator Protein-2 (AP-2) transcription factors are critically involved in a variety of fundamental cellular processes such as proliferation, differentiation and apoptosis and have also been implicated in carcinogenesis. Expression of the family members AP-2α and AP-2γ is particularly well documented in malignancies of the female breast. Despite increasing evaluation of single AP-2 isoforms in ma...... hiện toàn bộ
Impact of a one-year supervised physical activity program on long-term cancer-related fatigue and mediating effects of the gut microbiota in metastatic testicular cancer patients: protocol of the prospective multicentre, randomized controlled phase-III STARTER trial
BMC Cancer - - 2024
Hwayoung Noh, Amélie Anota, Rodolf Mongondry, Renaud Meyrand, Carmen Dupuis, Camille Schiffler, Philippe Marijnen, Sabina Rinaldi, Joel Lachuer, Pekka Keski-Rahkonen, Marc J Gunter, Aude Fléchon, Béatrice Fervers, Olivia Pérol
Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–40 years, with increasing incidence worldwide. About 33 ~ 50% of the patients present with metastatic disease at diagnosis. TGCT survivors experience short- and long-term sequelae, including cancer-related fatigue (CRF). Physical activity (PA) has established effects on reducing CRF and other sequelae and improving ...... hiện toàn bộ
The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time
BMC Cancer - Tập 10 - Trang 1-9 - 2010
Junliang Ma, Lunxu Liu, Guowei Che, Nanbin Yu, Fuqiang Dai, Zongbing You
Tumor-associated macrophages (TAMs) play an important role in growth, progression and metastasis of tumors. In non-small cell lung cancer (NSCLC), TAMs' anti-tumor or pro-tumor role is not determined. Macrophages are polarized into M1 (with anti-tumor function) and M2 (with pro-tumor function) forms. This study was conducted to determine whether the M1 and M2 macrophage densities in NSCLC are asso...... hiện toàn bộ
Introduction of a breast cancer care programme including ultra short hospital stay in 4 early adopter centres: framework for an implementation study
BMC Cancer - Tập 7 - Trang 1-9 - 2007
Mascha de Kok, Caroline NA Frotscher, Trudy van der Weijden, Alfons GH Kessels, Carmen D Dirksen, Cornelis JH van de Velde, Jan A Roukema, Antoine VRJ Bell, Fred W van der Ent, Maarten F von Meyenfeldt
Whereas ultra-short stay (day care or 24 hour hospitalisation) following breast cancer surgery was introduced in the US and Canada in the 1990s, it is not yet common practice in Europe. This paper describes the design of the MaDO study, which involves the implementation of ultra short stay admission for patients after breast cancer surgery, and evaluates whether the targets of the implementation s...... hiện toàn bộ
Effect of cachexia on bone turnover in cancer patients: a case-control study
BMC Cancer - - 2021
Hannes Zwickl, Elisabeth Zwickl-Traxler, Alexander Haushofer, Josef Seier, Klaus Podar, Michael Weber, Klaus Hackner, Nico Jacobi, Martin Pecherstorfer, Sonia Vallet
Abstract Background Increased bone turnover is frequently observed in advanced cancer and predominantly related to bone metastases or therapy. Cachexia represents an important cause of morbidity and mortality in cancer patients. Key features are weight loss, muscle wasting and chronic inflammation, ...... hiện toàn bộ
Cell fusion between gastric epithelial cells and mesenchymal stem cells results in epithelial-to-mesenchymal transition and malignant transformation
BMC Cancer - Tập 15 - Trang 1-11 - 2015
Xianghui He, Baosong Li, Yang Shao, Na Zhao, Yiling Hsu, Zhixiang Zhang, Liwei Zhu
The discovery of cancer stem cells and tumor heterogeneity prompted the exploration of additional mechanisms aside from genetic mutations for carcinogenesis and cancer progression. The aim of the present study was to investigate the effect of cell fusion between mesenchymal stem cells and the gastric epithelial cells in tumorigenesis. Cell fusion between cord blood mesenchymal stem cells and human...... hiện toàn bộ
Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma – a case report
BMC Cancer - Tập 19 - Trang 1-6 - 2019
Chu-Wen Fang, Jyh-Seng Wang, Tony T. Wu, Jen-Tai Lin
Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the retroperitoneum and posterior mediastinum. Other reported rare sites include the adrenal gland, small intestine, colon and urinary bladder. However, para-testicular GNs are even more rare. H...... hiện toàn bộ
Aberrant Promoter Methylation of YAP Gene and its Subsequent Downregulation in Indian Breast Cancer Patients
BMC Cancer - - 2018
Sumayya Abdul Sattar Real, Farah Parveen, Asad Ur Rehman, Mateen A. Khan, S. V. S. Deo, Nootan Kumar Shukla
Development and validation of a radiopathomic model for predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer patients
BMC Cancer - Tập 23 - Trang 1-12 - 2023
Jieqiu Zhang, Qi Wu, Wei Yin, Lu Yang, Bo Xiao, Jianmei Wang, Xiaopeng Yao
Neoadjuvant chemotherapy (NAC) has become the standard therapeutic option for early high-risk and locally advanced breast cancer. However, response rates to NAC vary between patients, causing delays in treatment and affecting the prognosis for patients who do not sensitive to NAC. In total, 211 breast cancer patients who completed NAC (training set: 155, validation set: 56) were retrospectively en...... hiện toàn bộ
Tổng số: 11,114   
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