Artificial Organs

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Hemodiafiltration: A New Alternative To Hemofiltration And Conventional Hemodialysis*
Artificial Organs - Tập 2 Số 2 - Trang 150-153 - 1978
H. W. Leber, V. Wizemann, G Goubeaud, P Rawer, G Schütterle
ABSTRACTA new dialysis method, termed hemodiafiltration, is proposed. The procedure consists of the combination of hemofiltration and conventional hemodialysis using high flux membranes with a transmembrane pressure (TMP) of 300–500 mmHg and a dialysate flow of 900 ml/min. Due to the combination of convective mass transfer and diffusion, the clearance values of bot...... hiện toàn bộ
Out‐of‐Center Extracorporeal Membrane Oxygenation for Adult Cardiogenic Shock Patients
Artificial Organs - Tập 30 Số 1 - Trang 24-28 - 2006
Shu‐Chien Huang, Yih‐Sharng Chen, Nai‐Hsin Chi, Jiun Hsu, Chih‐Hsien Wang, Hsi‐Yu Yu, Nai‐Kuan Chou, Wen‐Je Ko, Shoei‐Shen Wang, Fang‐Yue Lin
Abstract:  Patients with cardiogenic shock refractory to conventional management require advanced mechanical circulatory support such as extracorporeal membrane oxygenation (ECMO). In hospitals lacking ECMO facilities, interhospital transportation is necessary for further patient management. Thirty‐one adult cardiac patients, who were transported to our hospital by o...... hiện toàn bộ
Development of a Bioartificial Liver Using Isolated Hepatocytes
Artificial Organs - Tập 18 Số 5 - Trang 371-384 - 1994
Vivek Dixit
Abstract: Severe liver disease is very often life‐threatening and dramatically diminishes quality of life. Liver support systems based on detoxification alone have been proved ineffective because they cannot correct biochemical disorders. An effective artificial liver support system should be capable of carrying out the liver's essential processes, such as synthetic...... hiện toàn bộ
Clinical Evaluation of Two Different Extracorporeal Membrane Oxygenation Systems: A Single Center Report
Artificial Organs - Tập 35 Số 7 - Trang 733-737 - 2011
Kun Yu, Cun Long, Feilong Hei, Jingwen Li, Jinping Liu, Bingyang Ji, Guodong Gao, Haitao Zhang, Yunhu Song, Wei Wang
AbstractRefinements in extracorporeal membrane oxygenation (ECMO) equipment, including heparin‐coated surfaces, centrifugal pump, membrane oxygenator, and more biocompatible pump‐oxygenator circuits, have reduced procedure‐related complications and have made ECMO a safe and effective therapy for critical patients. The aim of this study was to evaluate the performan...... hiện toàn bộ
Antithrombin Replacement During Extracorporeal Membrane Oxygenation
Artificial Organs - Tập 35 Số 11 - Trang 1024-1028 - 2011
Robert A. Niebler, Melissa Christensen, Richard J. Berens, Heidi Wellner, Theresa Mikhailov, James S. Tweddell
Assessment of an Extracorporeal Liver Assist Device in Anhepatic Dogs
Artificial Organs - Tập 16 Số 4 - Trang 418-422 - 1992
James H. Kelly, Tarek Koussayer, Da-Er He, Maria G. Chong, Thomas A. Shang, Hartwell H. Whisennand, Norman Sussman
Abstract: We have used an anhepatic dog model to demonstrate the efficacy of a bioartificial liver assist device. Six dogs underwent total hepatectomy. Three received only medical care (controls) while the remainder were connected to an extracorporeal liver assist device (ELAD). The control dogs failed to regain consciousness after anesthesia although all lived 4–5 ...... hiện toàn bộ
The Hepatix Extracorporeal Liver Assist Device: Initial Clinical Experience
Artificial Organs - Tập 18 Số 5 - Trang 390-396 - 1994
Norman Sussman, Gardar T. Gislason, Carol Conlin, James H. Kelly
Abstract: Eleven patients were treated with the Hepatix extracorporeal liver assist device (ELAD) between June 1991 and August 1993. The first 2 patients were treated according to Food and Drug Administration guidelines (“Emergency Use of Unapproved Medical Devices,” October 22, 1985), and the remaining 9 were treated according to an Investigational Device Exemption...... hiện toàn bộ
Higher Renal Replacement Therapy Dose Delivery Influences on Drug Therapy
Artificial Organs - Tập 27 Số 9 - Trang 808-814 - 2003
Bruce A. Mueller, Deborah A. Pasko, Kevin M. Sowinski
Abstract: Higher doses of renal replacement therapy have profound effects on pharmacotherapy, yet little research has been conducted in this area. High‐volume renal replacement therapies influence both the pharmacokinetic and the pharmacodynamic profiles of all drugs administered to these critically ill patients. Intermittent high‐dose “hybrid” hemodialysis therapies...... hiện toàn bộ
Comparison of Sustained Hemodiafiltration With Continuous Venovenous Hemodiafiltration for the Treatment of Critically Ill Patients With Acute Kidney Injury
Artificial Organs - Tập 34 Số 4 - Trang 331-338 - 2010
Masanori Abe, Kazuyoshi Okada, Midori Suzuki, Chinami Nagura, Yuko Ishihara, Yuki Fujii, Kazuya Ikeda, Kazo Kaizu, Koichi Matsumoto
AbstractDespite improvements in medical care, the mortality of critically ill patients with acute kidney injury (AKI) who require renal replacement therapy (RRT) remains high. We describe a new approach, sustained hemodiafiltration, to treat patients who suffered from acute kidney injury and were admitted to intensive care units (ICUs). In our study, 60 critically ...... hiện toàn bộ
New Method to Calculate Creatinine Generation Rate Using Pre‐ and Postdialysis Creatinine Concentra tions
Artificial Organs - Tập 21 Số 8 - Trang 864-872 - 1997
Toru Shinzato, Shigeru Nakai, Masamiki Miwa, Norihisa Iwayama, Ichiro Takai, Yoshihiro Matsumoto, Hiroyuki Morita, Kenji Maeda
Abstract: The creatinine (Cr) generation rate reflects the muscle mass, a possible indicator of protein nutritional status. Thus, in this study, we developed equations for calculating the Cr generation rate. Depner and Daugirdas recently developed a method for determining the protein catabolic rate (PCR) from the pre‐ and postdialysis blood urea nitrogen concentrati...... hiện toàn bộ
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