Hemodiafiltration: A New Alternative To Hemofiltration And Conventional Hemodialysis*

Artificial Organs - Tập 2 Số 2 - Trang 150-153 - 1978
H. W. Leber1, V. Wizemann1, G Goubeaud1, P Rawer1, G Schütterle1
1Zentrum für Innere Medizin, Universitätskliniken Giessen, Federal Republic of Germany

Tóm tắt

ABSTRACTA new dialysis method, termed hemodiafiltration, is proposed. The procedure consists of the combination of hemofiltration and conventional hemodialysis using high flux membranes with a transmembrane pressure (TMP) of 300–500 mmHg and a dialysate flow of 900 ml/min. Due to the combination of convective mass transfer and diffusion, the clearance values of both small and larger molecules are significantly higher than during hemofiltration or hemodialysis alone with the same membranes. The removal of excess water is better tolerated than during hemodialysis. With this new method, six patients have been successfully treated for six months (three times per week, three hours per treatment) without side effects. Thus, hemodiafiltration appears to be the method of choice to shorten dialysis time.

Từ khóa


Tài liệu tham khảo

Bergström J., 1976, Dialysis, ultrafiltration and blood pressure, Proc Eur Dial Transplant Assoc, 13, 293

Henderson L. W., 1967, Blood purification by ultrafiltration and fluid replacement (diafiltration), Trans Am Soc Artif Intern Organs, 13, 216

10.1097/00002480-197301900-00022

Quellhorst E., 1976, Treatment of chronic uremia by an ultrafiltration kidney—first clinical results, Proc Eur Dial Transplant Assoc, 13, 314

Henderson L. W., 1975, Kinetics of hemofiltration. II. Clinical characterization of a new blood cleansing modality, J Lab Clin Med, 85, 372

Leber H. W. Wizemann V. Goubeaud G. Rawer P.Hemodiafiltration: an effective alternative to hemofiltration and conventional hemodialysis in the treatment of uremic patients(in press).

Thông tin
Thông tin xuất bản

Artificial Organs

Tập 2 Số 2

150-153

Thông tin tác giả