Molecular Adsorbent Recycling System (MARS): Clinical Results of a New Membrane‐Based Blood Purification System for Bioartificial Liver Support Tập 23 Số 4 - Trang 319-330 - 1999
Stange, Mitzner, Risler, Erley, Lauchart, Goehl, Sebastian Klammt, Peszynski, Freytag, Hickstein, Matthias Löhr, Liebe, Schareck, Hopt, Schmidt
The use of xenogenic or genetically engineered cell types in bioartificial liver support systems requires separation methods between the patients' blood and the liver support bioreactors that guarantee the sufficient transfer of pathophysiologically relevant substances but prevent complications. The present paper describes a new membrane separation system that is nearly impermeable to prot...... hiện toàn bộ The Hepatix Extracorporeal Liver Assist Device: Initial Clinical Experience Tập 18 Số 5 - Trang 390-396 - 1994
Norman Sussman, Gardar T. Gislason, Carol Conlin, James H. Kelly
Abstract: Eleven patients were treated with the Hepatix extracorporeal liver assist device (ELAD) between June 1991 and August 1993. The first 2 patients were treated according to Food and Drug Administration guidelines (“Emergency Use of Unapproved Medical Devices,” October 22, 1985), and the remaining 9 were treated according to an Investigational Device Exemption...... hiện toàn bộ Study on Biocompatibility of Complexes of Collagen–Chitosan–Sodium Hyaluronate and Cornea Tập 29 Số 2 - Trang 104-113 - 2005
Jiansu Chen, Qinghua Li, Jintang Xu, Yao‐Xiong Huang, Yong Ding, Hongwei Deng, Songbin Zhao, Rui Chen
Abstract: In this study we investigated the biocompatibility of collagen–chitosan–sodium hyaluronate (Col–Chi–NaHA) complexes and cornea tissue, and the feasibility of Col–Chi–NaHA complexes as substrates for cultivating rabbit corneal cells. Different components of Col–Chi–NaHA complexes were prepared and tested. A circular complex film with a diameter of 6 mm was ...... hiện toàn bộ Development of a Bioartificial Liver Using Isolated Hepatocytes Tập 18 Số 5 - Trang 371-384 - 1994
Vivek Dixit
Abstract: Severe liver disease is very often life‐threatening and dramatically diminishes quality of life. Liver support systems based on detoxification alone have been proved ineffective because they cannot correct biochemical disorders. An effective artificial liver support system should be capable of carrying out the liver's essential processes, such as synthetic...... hiện toàn bộ Effects of a Chitosan Scaffold Containing TGF‐β1 Encapsulated Chitosan Microspheres on In Vitro Chondrocyte Culture Tập 28 Số 9 - Trang 829-839 - 2004
Jong Eun Lee, Seoung Eun Kim, Ick Chan Kwon, Hyun Jeong Ahn, Cho Hyun-Chul, Sang‐Hoon Lee, Hee Joong Kim, Sang Cheol Seong, Myung Chul Lee
Abstract: The objectives of this study were (1) to develop a three‐dimensional chitosan scaffold in combination with transforming growth factor‐beta1 (TGF‐β1)‐loaded chitosan microspheres and (2) to evaluate the effect of the TGF‐β1 release on the chondrogenic potential of rabbit chondrocytes in the scaffolds. TGF‐β1 was loaded into chitosan microspheres usi...... hiện toàn bộ New Method to Calculate Creatinine Generation Rate Using Pre‐ and Postdialysis Creatinine Concentra tions Tập 21 Số 8 - Trang 864-872 - 1997
Toru Shinzato, Shigeru Nakai, Masamiki Miwa, Norihisa Iwayama, Ichiro Takai, Yoshihiro Matsumoto, Hiroyuki Morita, Kenji Maeda
Abstract: The creatinine (Cr) generation rate reflects the muscle mass, a possible indicator of protein nutritional status. Thus, in this study, we developed equations for calculating the Cr generation rate. Depner and Daugirdas recently developed a method for determining the protein catabolic rate (PCR) from the pre‐ and postdialysis blood urea nitrogen concentrati...... hiện toàn bộ