Effect of long-term remote ischemic conditioning in patients with chronic ischemic heart failureArchiv für Kreislaufforschung - Tập 112 - Trang 1-11 - 2017
Kasper Pryds, Roni Ranghøj Nielsen, Anders Jorsal, Mona Sahlholdt Hansen, Steffen Ringgaard, Jens Refsgaard, Won Yong Kim, Annemette Krintel Petersen, Hans Erik Bøtker, Michael Rahbek Schmidt
Remote ischemic conditioning (RIC) protects against acute ischemia–reperfusion injury and may also have beneficial effects in patients with stable cardiovascular disease. We investigated the effect of long-term RIC treatment in patients with chronic ischaemic heart failure (CIHF). In a parallel group study, 22 patients with compensated CIHF and 21 matched control subjects without heart failure or ...... hiện toàn bộ
Release kinetics and correlation with hemodynamic dysfunction of cardiac troponin T in coronary effluent from isolated rat hearts during reperfusionArchiv für Kreislaufforschung - Tập 88 - Trang 307-313 - 1993
Y. Yamahara, J. Asayama, B. Ohta, T. Matsumoto, H. Miyazaki, T. Tatsumi, M. Kobara, M. Inoue, D. Inoue, M. Nakagawa
Previously, we reported that cardiac troponin T (TnT) can be detected and measured in coronary effluent from isolated rat hearts during hypoxia. The present study was designed to evaluate the release kinetics of TnT from post-ischemic rat hearts. Using the Langendorff technique, the hearts were reperfused for 4h after 20 min or 60 min of global ischemia. Coronary flow was measured by timing the co...... hiện toàn bộ
Further studies on the effects of myosin P-light chain phosphorylation on contractile properties of skinned cardiac fibresArchiv für Kreislaufforschung - Tập 81 - Trang 611-619 - 1986
I. Morano, H. Arndt, C. Bächle-Stolz, J. C. Rüegg
We investigated the influence of myosin P-light chain phosphorylation by Ca2+-calmodulin dependent myosin light chain kinase (MLCK) on the sensitivity of the tension-pCa relation and maximum unloaded shortening velocity (v
max) of chemically skinned heart fibres of the pig. Submaximum Ca2+ stimulation (pCa 5.5) induced 20±5% of the isometric tension achieved at maximum Ca2+ activation (pCa 4.3). M...... hiện toàn bộ
Doppler myocardial imaging. A new tool to assess regional inhomogeneity in cardiac functionArchiv für Kreislaufforschung - Tập 96 - Trang 595-605 - 2001
Frank Weidemann, Miroslaw Kowalski, Jan D'hooge, Bart Bijnens, George R. Sutherland
In echocardiography, there is still a need for a better tool to quantify regional myocardial function. Doppler myocardial imaging (DMI) allows the calculation of local myocardial velocity profiles for segmental motion in both the radial and longitudinal direction. From the local velocity profile data, 1-dimensional regional myocardial strain rates (SR) and strain (ε) can now be calculated. These ...... hiện toàn bộ
Aging-associated insulin resistance predisposes to hypertension and its reversal by exercise: the role of vascular vasorelaxation to insulinArchiv für Kreislaufforschung - Tập 104 - Trang 269-284 - 2008
Qiu-Xia Li, Zheng-Ying Xiong, Bai-Ping Hu, Zhen-Jun Tian, Hai-Feng Zhang, Wen-Yi Gou, Hai-Chang Wang, Feng Gao, Quan-Jiang Zhang
Aging is an independent risk factor for hypertension, and hypertension and insulin resistance commonly coexist in the elderly. This study was designed to examine the effects of aging-related insulin resistance on blood pressure (BP) and its underlying mechanisms, with specific focus on the role of exercise in reversing hypertensive response. Adult (6-month-old) and aging (24-month-old) male Spragu...... hiện toàn bộ
Structural and functional imaging by MRIArchiv für Kreislaufforschung - Tập 103 - Trang 152-160 - 2008
René M. Botnar, Eike Nagel
Magnetic resonance imaging is one of the most exciting techniques for noninvasive molecular imaging of the cardiovascular system. The article will describe challenges, solutions and results of magnetic resonance plaque imaging ex-vivo, in the experimental animal and in patients.