Annual Review of Cell and Developmental Biology
SCIE-ISI SCOPUS (1995-2022)
1530-8995
1081-0706
Mỹ
Cơ quản chủ quản: Annual Reviews Inc. , ANNUAL REVIEWS
Lĩnh vực:
Cell BiologyDevelopmental Biology
Các bài báo tiêu biểu
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE▪ Abstract Tight control of cell-cell communication is essential for the generation of a normally patterned embryo. A critical mediator of key cell-cell signaling events during embryogenesis is the highly conserved Wnt family of secreted proteins. Recent biochemical and genetic analyses have greatly enriched our understanding of how Wnts signal, and the list of canonical Wnt signaling com... ... hiện toàn bộ
Tập 20 Số 1 - Trang 781-810 - 2004
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular VesiclesIn the 1980s, exosomes were described as vesicles of endosomal origin secreted from reticulocytes. Interest increased around these extracellular vesicles, as they appeared to participate in several cellular processes. Exosomes bear proteins, lipids, and RNAs, mediating intercellular communication between different cell types in the body, and thus affecting normal and pathological condition... ... hiện toàn bộ
Tập 30 Số 1 - Trang 255-289 - 2014
How Matrix Metalloproteinases Regulate Cell Behavior▪ Abstract The matrix metalloproteinases (MMPs) constitute a multigene family of over 25 secreted and cell surface enzymes that process or degrade numerous pericellular substrates. Their targets include other proteinases, proteinase inhibitors, clotting factors, chemotactic molecules, latent growth factors, growth factor–binding proteins, cell surface receptors, cell-cell adhesion molecul... ... hiện toàn bộ
Tập 17 Số 1 - Trang 463-516 - 2001
QUORUM SENSING: Cell-to-Cell Communication in Bacteria Bacteria communicate with one another using chemical signal molecules. As in higher organisms, the information supplied by these molecules is critical for synchronizing the activities of large groups of cells. In bacteria, chemical communication involves producing, releasing, detecting, and responding to small hormone-like molecules termed autoinducers . This process, termed quorum sensin... ... hiện toàn bộ
Tập 21 Số 1 - Trang 319-346 - 2005
RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINS ▪ Abstract Proteins that contain the Arg-Gly-Asp (RGD) attachment site, together with the integrins that serve as receptors for them, constitute a major recognition system for cell adhesion. The RGD sequence is the cell attachment site of a large number of adhesive extracellular matrix, blood, and cell surface proteins, and nearly half of the over 20 known integrins recognize this sequen... ... hiện toàn bộ
Tập 12 Số 1 - Trang 697-715 - 1996
FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES▪ Abstract Recent studies showing that detergent-resistant membrane fragments can be isolated from cells suggest that biological membranes are not always in a liquid-crystalline phase. Instead, sphingolipid and cholesterol-rich membranes such as plasma membranes appear to exist, at least partially, in the liquid-ordered phase or a phase with similar properties. Sphingolipid and cholestero... ... hiện toàn bộ
Tập 14 Số 1 - Trang 111-136 - 1998
RHO GTPASES: Biochemistry and BiologyApproximately one percent of the human genome encodes proteins that either regulate or are regulated by direct interaction with members of the Rho family of small GTPases. Through a series of complex biochemical networks, these highly conserved molecular switches control some of the most fundamental processes of cell biology common to all eukaryotes, including morphogenesis, polarity, move... ... hiện toàn bộ
Tập 21 Số 1 - Trang 247-269 - 2005
The Role of Atg Proteins in Autophagosome Formation Macroautophagy is mediated by a unique organelle, the autophagosome, which encloses a portion of cytoplasm for delivery to the lysosome. Autophagosome formation is dynamically regulated by starvation and other stresses and involves complicated membrane reorganization. Since the discovery of yeast Atg-related proteins, autophagosome formation has been dissected at the molecular level. In t... ... hiện toàn bộ
Tập 27 Số 1 - Trang 107-132 - 2011
Liquid-Liquid Phase Separation in Biology Cells organize many of their biochemical reactions in non-membrane compartments. Recent evidence has shown that many of these compartments are liquids that form by phase separation from the cytoplasm. Here we discuss the basic physical concepts necessary to understand the consequences of liquid-like states for biological functions.
Tập 30 Số 1 - Trang 39-58 - 2014
Biochemical Pathways of Caspase Activation During Apoptosis ▪ Abstract Caspase activation plays a central role in the execution of apoptosis. The key components of the biochemical pathways of caspase activation have been recently elucidated. In this review, we focus on the two most well-studied pathways of caspase activation: the cell surface death receptor pathway and the mitochondria-initiated pathway. In the cell surface death receptor pathway... ... hiện toàn bộ
Tập 15 Số 1 - Trang 269-290 - 1999