Khoa D. Nguyen, Christopher Vanichsarn, Kari Nadeau
Abstract Background Even though thymic stromal lymphopoietin (TSLP) has been
implicated in the development of allergic inflammation, its influence on immune
tolerance mediated by regulatory T cells (Treg) have not been explored. We aimed
to dissect the influence of TSLP on immunosuppressive activities of Treg and its
potential consequences in human allergic asthma. Methods I n vitro culture
system... hiện toàn bộ
Antonino Romano, Marinella Viola, Francesco Gaeta, Gabriele Rumi, Michela Maggioletti
Abstract The present review addresses the literature regarding the sensitivity
and specificity of the various diagnostic methods for evaluating non-immediate
(ie, occurring more than 1 hour after drug administration) hypersensitivity
reactions associated with β-lactams and other antibiotics, anticonvulsants,
heparins, iodinated contrast media, etc. Such reactions include several clinical
entities,... hiện toàn bộ
Abstract Chronic spontaneous urticaria (CSU) is often associated with organ
specific autoimmunity but is rarely caused by food allergy. Colourings and
preservatives in pre-packaged foods, so called pseudoallergens, have also been
implicated. Factors that promote inflammation or reduce anti-inflammatory
mechanisms may however, predispose susceptible individuals to CSU. Chronic
underlying infection ... hiện toàn bộ