Allergy, Asthma & Clinical Immunology

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Evaluation of nasal symptoms induced by platelet activating factor, after nasal challenge in both healthy and allergic rhinitis subjects pretreated with rupatadine, levocetirizine or placebo in a cross-over study design
Allergy, Asthma & Clinical Immunology - Tập 9 - Trang 1-5 - 2013
Rosa Muñoz-Cano, Antonio Valero, Ignacio Izquierdo, Jaume Sánchez-López, Alejandro Doménech, Joan Bartra, Joaquim Mullol, Cesar Picado
Platelet-activating factor (PAF) is produced by most inflammatory cells and it is involved in inflammatory and allergic reactions. We aimed to assess the anti-PAF effects of rupatadine and levocetirizine in the upper airways. Healthy volunteers (HV, N = 10) and seasonal allergic rhinitis (SAR, N = 10) asymptomatic patients were treated out of the pollen season with either rupatadine 20 mg, levocet...... hiện toàn bộ
Plasma cytokine profiles associated with rhodesiense sleeping sickness and falciparum malaria co-infection in North Eastern Uganda
Allergy, Asthma & Clinical Immunology - Tập 15 - Trang 1-13 - 2019
Julius Nsubuga, Charles Drago Kato, Ann Nanteza, Enock Matovu, Vincent Pius Alibu
Immunological Human African Trypanosomiasis (HAT) studies often exclude malaria, although both infections overlap in specific endemic areas. During this co-infection, it is not known whether this parasitic interaction induces synergistic or antagonistic cytokine response among humans. This study determined prevalence of Plasmodium falciparum malaria among Trypanosoma brucei rhodesiense HAT and pla...... hiện toàn bộ
Structural alterations and markers of endothelial activation in pulmonary and bronchial arteries in fatal asthma
Allergy, Asthma & Clinical Immunology - Tập 15 - Trang 1-9 - 2019
Renata Calciolari Rossi, Raquel Anonni, Diogenes Seraphim Ferreira, Luiz Fernando Ferraz da Silva, Thais Mauad
There is interest in better understanding vessel pathology in asthma, given the findings of loss of peripheral vasculature associated with disease severity by imaging and altered markers of endothelial activation. To date, vascular changes in asthma have been described mainly at the submucosal capillary level of the bronchial microcirculation, with sparse information available on the pathology of ...... hiện toàn bộ
Clinical validation of controlled exposure to house dust mite in the environmental exposure unit (EEU)
Allergy, Asthma & Clinical Immunology - Tập 17 - Trang 1-14 - 2021
Lubnaa Hossenbaccus, Sophia Linton, Jenny Thiele, Lisa Steacy, Terry Walker, Crystal Malone, Anne K. Ellis
The Environmental Exposure Unit (EEU), a controlled allergen exposure model of allergic rhinitis (AR), has traditionally utilized seasonal allergens. We sought to clinically validate the use of house dust mite (HDM), a perennial allergen, in the HDM-EEU, a specially designed facility within the larger EEU. Forty-four HDM-allergic and eleven non-allergic participants were screened and deemed eligib...... hiện toàn bộ
Subcutaneous immunotherapy induces alterations in monocytes and dendritic cells homeostasis in allergic rhinitis patients
Allergy, Asthma & Clinical Immunology - Tập 14 - Trang 1-13 - 2018
Letícia Sousa, Carmen Martín-Sierra, Celso Pereira, Graça Loureiro, Beatriz Tavares, Susana Pedreiro, António Martinho, Artur Paiva
Specific subcutaneous immunotherapy (SCIT) can achieve long-term remission in patients with allergic rhinitis (AR) through complex and still unknown mechanisms. The aim of this study is to evaluate the effect of SCIT over CD16+ and CD16− monocytes, myeloid (mDCs) and plasmacytoid dendritic cells (pDCs) in patients with AR, comparatively to pharmacological standard treatment (non-SIT). The relative...... hiện toàn bộ
Frequency of CD4+ and CD8+ T cells in Iranian chronic rhinosinusitis patients
Allergy, Asthma & Clinical Immunology - Tập 14 - Trang 1-11 - 2018
Farhad Seif, Babak Ghalehbaghi, Hossein Aazami, Alireza Mohebbi, Aslan Ahmadi, Reza Falak, Pegah Babaheidarian, Mohammad Najafi, Majid Khoshmirsafa, Sahand Ghalehbaghi, Mehdi Shekarabi
Chronic Rhinosinusitis (CRS) is a persistent inflammatory disease affecting paranasal sinuses. CRS is categorized into two distinct subgroups defined as CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Although several immune cells are involved in the CRS pathogenesis, the role of T cells is not fully understood. The objective of the present study was to evaluate the frequency...... hiện toàn bộ
Proceedings of the Canadian Society of Allergy and Clinical Immunology Annual Scientific Meeting 2018
Allergy, Asthma & Clinical Immunology - - 2019
Jihoon Choi, Christoffer Dharma, Amel Lamri, Amirthagowri Ambalavanan, Diana L. Lefebvre, Stuart E. Turvey, Piushkumar J. Mandhane, A.B. Becker, Meghan B. Azad, Theo J. Moraes, Malcolm R. Sears, Padmaja Subbarao, Qingling Duan, Ahmad A. Alzahrani, Elinor Simons, Anne K. Ellis, Jaclyn Parks, Jeffrey R. Brook, James A. Scott, Anita L. Kozyrskyj, Lawrence C. McCandless, Tim K. Takaro, Jason Lee, Suvina Amin, Michelle Erdmann, Atif Kukaswadia, Jelena Ivanović, Aren Fischer, Alain Gendron
Allergy to sunflower seed and sunflower butter as proposed vehicle for sensitization
Allergy, Asthma & Clinical Immunology - - 2015
Elana Lavine, Moshe Ben‐Shoshan
Characterizing telemedicine use in clinical immunology and allergy in Canada before the COVID-19 pandemic
Allergy, Asthma & Clinical Immunology - Tập 17 - Trang 1-5 - 2021
Erika Yue Lee, Christine Song, Peter Vadas, Matthew Morgan, Stephen Betschel
There exists a geographic barrier to access CIA care for patients who live in rural communities; telemedicine may bridge this gap in care. Herein we characterized the use of telemedicine in CIA at a population-based level and single centre. Before the COVID-19 pandemic, telemedicine care was provided via the Ontario Telemedicine Network (OTN) in Ontario, Canada. Descriptive data were collected fro...... hiện toàn bộ
The complexities of insulin allergy: a case and approach
Allergy, Asthma & Clinical Immunology - Tập 17 - Trang 1-10 - 2021
Babak Aberumand, Samira Jeimy
Insulin hypersensitivity is rare, but challenging for individuals with diabetes. The prevalence of insulin allergy has decreased since the introduction of human recombinant insulin preparations. Hypersensitivity reactions range from injection site erythema and swelling, to anaphylaxis. While some reactions are to excipients (zinc, protamine, metacresol), many are to recombinant insulin itself. We ...... hiện toàn bộ
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