Alimentary Pharmacology and Therapeutics
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Long-term results of treatment of malignant carcinoid syndrome with prolonged release Lanreotide (Somatuline Autogel)
Alimentary Pharmacology and Therapeutics - Tập 34 Số 2 - Trang 235-242 - 2011
Long‐term results of patients with malignant carcinoid syndrome receiving octreotide LAR
Alimentary Pharmacology and Therapeutics - Tập 30 Số 7 - Trang 733-740 - 2009
SummaryBackground Octreotide LAR is an established treatment for malignant
carcinoid syndrome. However, studies with large number of patients and long
follow‐up are lacking.Aim To present long‐terms results with octreotide LAR,
assessing duration of clinical and objective response and treatment tolerance,
in a large, homogeneous cohort of patients with malignant carcinoid
syndrome.Methods A tot...
Sandostatin LAR (long‐acting octreotide acetate) for malignant carcinoid syndrome: a 3‐year experience
Alimentary Pharmacology and Therapeutics - Tập 17 Số 3 - Trang 437-444 - 2003
SummaryBackground : Somatostatin analogues are the best therapy for controlling
the symptoms of malignant carcinoid syndrome. Octreotide acetate given as
subcutaneous injection up to three times daily, intramuscular Lanreotide
injection given once per 1–2 weeks and monthly intramuscular Sandostatin LAR
have demonstrated similar efficacy in short‐term studies.Aim : To assess the
long‐term effect of...
Gastric emptying and different types of reflux in adult patients with cystic fibrosis
Alimentary Pharmacology and Therapeutics - Tập 34 Số 7 - Trang 799-807 - 2011
Herbal medicinal products for non‐ulcer dyspepsia
Alimentary Pharmacology and Therapeutics - Tập 16 Số 10 - Trang 1689-1699 - 2002
SummaryBackground : Non‐ulcer dyspepsia is predominantly a self‐managed
condition, although it accounts for a significant number of general practitioner
consultations and hospital referrals. Herbal medicinal products are often used
for the relief of dyspeptic symptoms.Aims : To critically assess the evidence
for and against herbal medicinal products for the treatment of non‐ulcer
dyspepsia.Methods...
Randomised clinical trial: gut microbiome biomarkers are associated with clinical response to a low FODMAP diet in children with the irritable bowel syndrome
Alimentary Pharmacology and Therapeutics - Tập 42 Số 4 - Trang 418-427 - 2015
SummaryBackgroundA low fermentable oligosaccharides, disaccharides,
monosaccharides and polyols (FODMAP) diet can ameliorate symptoms in adult
irritable bowel syndrome (IBS) within 48 h.AimTo determine the efficacy of a low
FODMAP diet in childhood IBS and whether gut microbial composition and/or
metabolic capacity are associated with its efficacy.MethodsIn a double‐blind,
crossover trial, childre...
Review article: is non‐alcoholic fatty liver disease a spectrum, or are steatosis and non‐alcoholic steatohepatitis distinct conditions?
Alimentary Pharmacology and Therapeutics - Tập 36 Số 9 - Trang 815-823 - 2012
SummaryBackgroundNon‐alcoholic fatty liver disease (NAFLD) is currently
conceptualised as a clinical spectrum that results from a ‘multiple‐hit’ process
which begins with simple steatosis and subsequently renders the hepatocytes
susceptible to a variety of insults. Ultimately, more serious liver injuries
like non‐alcoholic steatohepatitis (NASH) and cirrhosis may develop. Although
the metabolic sy...
Short‐chain fatty acid topical treatment in distal ulcerative colitis
Alimentary Pharmacology and Therapeutics - Tập 9 Số 3 - Trang 309-313 - 1995
SUMMARY Background: Some evidence indicates that short‐chain fatty acid (SCFA)
enemas are effective in the treatment of distal ulcerative colitis. Methods: In
a randomized, double‐blind, placebo‐controlled study, we tested the efficacy of
a 6‐week course of topical SCFA (100 mL, twice daily enemas of sodium acetate 80
mmol/L, sodium propionate 30 mmol/L and sodium butyrate 40 mmol/L) in 40
patient...
Review article: chronic viral infection in the anti‐tumour necrosis factor therapy era in inflammatory bowel disease
Alimentary Pharmacology and Therapeutics - Tập 31 Số 1 - Trang 20-34 - 2010
SummaryBackground Anti‐Tumour necrosis factor (TNF) therapy is now well
established in the treatment of inflammatory bowel disease and the risk of
opportunistic infection is recognized. However, specific considerations
regarding screening, detection, prevention and treatment of chronic viral
infections in the context of anti‐TNF therapy in inflammatory bowel disease are
not widely adopted in prac...
Ambulatory gastric pH monitoring: proper probe placement and normal values
Alimentary Pharmacology and Therapeutics - Tập 15 Số 8 - Trang 1155-1162 - 2001
Background: Gastric acid production may persist while patients are treated with
proton pump inhibitors. Twenty‐four‐hour intragastric pH monitoring is being
used to identify gastric acid in the stomach while on medical therapy.Aim: To
identify the optimal region of the stomach to demonstrate the presence of
gastric acid.Method: Probe locations confirmed with fluoroscopy after placement
and prior t...
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