Chapter 4 Genetics and Molecular Pathophysiology of Nav1.7‐Related Pain SyndromesAdvances in Genetics - Tập 63 - Trang 85 - 2008
Yang Yong, Dib‐Hajj Sulayman D., Waxman Stephen G.
SCN9A, the gene which encodes voltage‐gated sodium channel Nav1.7, is located on human chromosome 2 within a cluster of other members of this gene family. Nav1.7 is present at high levels in most peripheral nociceptive neurons in dorsal root ganglion (DRG) and in sympathetic neurons. In addition to its focal tissue‐specific expression, Nav1.7 is distinguished by its ability to amplify small depola...... hiện toàn bộ
A cosmic virosphereAdvances in Genetics - Tập 106 - Trang 101-107 - 2020
Predrag Slijepcevic, N. Chandra Wickramasinghe