Probing the Endocytic Pathways of the Filamentous Bacteriophage in Live Cells Using Ratiometric pH Fluorescent IndicatorAdvanced healthcare materials - Tập 4 Số 3 - Trang 413-419 - 2015
Ye Tian, Man Wu, H. Liu, Zhi Liu, Quan Zhou, Zhongwei Niu, Yong Huang
Viral nanoparticles have attracted extensive research interests in diverse applications of diagnosis and therapy. In particular, filamentous M13 bacteriophages have shown great potential in biomedical applications. However, its pathways entering into cells still remain unclear, and this greatly hinders its further use as a drug or gene carrier. Here, a ratiometric M13 pH probe is designed ...... hiện toàn bộ
Photoacoustic‐Enabled Self‐Guidance in Magnetic‐Hyperthermia Fe@Fe3O4 Nanoparticles for Theranostics In VivoAdvanced healthcare materials - Tập 7 Số 9 - 2018
Ping Zhou, Heng Zhao, Quan Wang, Zhiguo Zhou, Jing Wang, Guang Deng, Xiyou Wang, Qian Liu, Hong Yang, Shiping Yang
AbstractMagnetic nanoparticles have gained much interest for theranostics benefited from their intrinsic integration of imaging and therapeutic abilities. Herein, c(RGDyK) peptide PEGylated Fe@Fe3O4 nanoparticles (RGD‐PEG‐MNPs) are developed for photoacoustic (PA)‐enabled self‐guidance in tumor‐targeting magnetic hypertherm...... hiện toàn bộ
Stretchable, Multiplexed pH Sensors With Demonstrations on Rabbit and Human Hearts Undergoing IschemiaAdvanced healthcare materials - Tập 3 Số 1 - Trang 59-68 - 2014
Hyun‐Joong Chung, Matthew S. Sulkin, Jong‐Seon Kim, Camille Goudeseune, Hsin‐Yun Chao, Joseph W. Song, Sang Yoon Yang, Yu‐I Hsu, Roozbeh Ghaffari, Igor R. Efimov, John A. Rogers
AbstractStable pH is an established biomarker of health, relevant to all tissues of the body, including the heart. Clinical monitoring of pH in a practical manner, with high spatiotemporal resolution, is particularly difficult in organs such as the heart due to its soft mechanics, curvilinear geometry, heterogeneous surfaces, and continuous, complex rhythmic motion...... hiện toàn bộ
Neutralized Nanoparticle Composed of SS‐Cleavable and pH‐Activated Lipid‐Like Material as a Long‐Lasting and Liver‐Specific Gene Delivery SystemAdvanced healthcare materials - Tập 3 Số 8 - Trang 1222-1229 - 2014
Masami Ukawa, Hidetaka Akita, Yasuhiro Hayashi, Ryohei Ishiba, Kota Tange, Mamoru Arai, Kazuhiro Kubo, Yuriko Higuchi, Kazunori Shimizu, Satoshi Konishi, Mitsuru Hashida, Hideyoshi Harashima
Rational Design of Biomolecular Templates for Synthesizing Multifunctional Noble Metal Nanoclusters toward Personalized Theranostic ApplicationsAdvanced healthcare materials - Tập 5 Số 15 - Trang 1844-1859 - 2016
Yong Yu, Beverly Yin Leng Mok, Xian Jun Loh, Yen Nee Tan
Biomolecule‐templated or biotemplated metal nanoclusters (NCs) are ultrasmall (<2 nm) metal (Au, Ag) particles stabilized by a certain type of biomolecular template (e.g., peptides, proteins, and DNA). Due to their unique physiochemical properties, biotemplated metal NCs have been widely used in sensing, imaging, delivery and therapy. The overwhelming applications in these individual ar...... hiện toàn bộ
The Control of Mesenchymal Stem Cell Differentiation Using Dynamically Tunable Surface MicrogroovesAdvanced healthcare materials - Tập 3 Số 10 - Trang 1608-1619 - 2014
Tao Gong, Kun Zhao, Guang Yang, Jinrong Li, Hongmei Chen, Yuping Chen, Shaobing Zhou
Many studies have demonstrated the potential to modulate stem cell differentiation by using static material substrate surfaces. However, cells actually grow in a dynamically diverse microenvironment in vivo. The regulated signals to the differentiation provided by these materials should not be passive or static but be active and dynamic. To mimic the endogenous cell culture microenvironmen...... hiện toàn bộ