Acta Ophthalmologica

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Clinical evaluation of simultaneous confocal scanning laser ophthalmoscopy imaging combined with high‐resolution, spectral‐domain optical coherence tomography
Acta Ophthalmologica - Tập 88 Số 8 - Trang 842-849 - 2010
Hans‐Martin Helb, Peter Charbel Issa, Monika Fleckenstein, Steffen Schmitz‐Valckenberg, Hendrik P. N. Scholl, Anat Loewenstein, Nicole Eter, Frank G. Holz
Acta Ophthalmol. 2010: 88: 842–849Abstract.Purpose:  To evaluate the clinical relevance of a new diagnostic modality, simultaneous confocal scanning laser ophthalmoscopy (cSLO) and high‐speed, high‐resolution, spectral‐domain optical coherence tomography (OCT), for the visualization of macular pathologies.Methods:  OCT images and simultaneous recording of fluorescein angiography, indocyanine green... hiện toàn bộ
New parameters in assessment of human donor corneal stroma
Acta Ophthalmologica - Tập 95 Số 4 - 2017
Marie Borderie, Kate Grieve, Kristina Irsch, Djida Ghoubay, Cristina Georgeon, Céline de Sousa, L. Laroche, Vincent Borderie
AbstractPurposeTo provide quantitative parameters for assessment of human donor corneal stroma by imaging stromal features of diseased and normal human corneas with full‐field optical coherence microscopy (FFOCM), using confocal microscopy (CM) and histology as reference techniques.MethodsBowman's layer (BL) thickness and keratocyte density were assessed ex vivo in 23 human donor corneas and 27 hu... hiện toàn bộ
Cultivated oral mucosal epithelial transplantation for persistent epithelial defect in severe ocular surface diseases with acute inflammatory activity
Acta Ophthalmologica - Tập 92 Số 6 - 2014
Chie Sotozono, Tsutomu Inatomi, Takahiro Nakamura, Noriko Koizumi, Norihiko Yokoi, Mayumi Ueta, Kotone Matsuyama, Hideaki Kaneda, Masanori Fukushima, Shigeru Kinoshita
AbstractPurposeTo assess the clinical efficacy of cultivated oral mucosal epithelial transplantation (COMET) for the treatment of persistent epithelial defect (PED).MethodsWe treated 10 eyes of nine patients with PED (Stevens–Johnson syndrome: three eyes; thermal/chemical injury: five eyes; ocular cicatricial pemphigoid: two eyes) with COMET at Kyoto Prefectural University of Medicine, Kyoto, Japa... hiện toàn bộ
Evolution of light scattering and redox balance in the rat lens after in vivo exposure to close‐to‐threshold dose ultraviolet radiation
Acta Ophthalmologica - Tập 88 Số 7 - Trang 779-785 - 2010
Jing Wang, Stefan Löfgren, Xiuqin Dong, Konstantin Galichanin, Per G. Söderberg
Acta Ophthalmol. 2010: 88: 779–785Abstract.Purpose:  To investigate the evolution of cataract development and glutathione redox balance in the rat lens after in vivo close‐to‐threshold dose exposure to ultraviolet radiation (UVR) around 300 nm.Methods:  Three groups of 10 Sprague–Dawley rats were unilaterally exposed to 8 kJ/m2 UVR‐300 nm for 15 min, and a fourth group of 10 rats was kept without ... hiện toàn bộ
Unscheduled DNA synthesis in lens epithelium after in vivo exposure to UV radiation in the 300 nm wavelength region
Acta Ophthalmologica - Tập 64 Số 2 - Trang 162-168 - 1986
Per G. Söderberg, Bo Philipson, Bo Lindström
Abstract A quantitative autoradiographic method was developed to study the pattern of DNA synthesis in the rat lens epithelium after in vivo exposure to UV radiation in the 300 nm wavelength region. It was found that UV radiation (peak transmission = 298 nm, half‐width = ± 10 nm) induces unscheduled DNA synthesis and that the proportion of nuclei in S‐phase concurrently is reduced indicating an in... hiện toàn bộ
An objective and rapid method for the determination of light dissemination in the lens
Acta Ophthalmologica - Tập 68 Số 1 - Trang 44-52 - 1990
Per G. Söderberg, Enping Chen, Bo Lindström
Abstract. A method for the objective measurement of light dissemination in the lens was developed. There is an exponential relationship between the concentration of standard solutions and the intensity of light disseminated forwards. The light disseminated in non‐pathological lenses from Sprague Dawley rats was registered as the equivalent standard concentration, C, and then transformed to log10 (... hiện toàn bộ
Acute cataract in the rat after exposure to radiation in the 300 nm wavelength region A study of the macro‐, micro‐ and ultrastructure
Acta Ophthalmologica - Tập 66 Số 2 - Trang 141-152 - 1988
PG SÖDERBERG
AbstractExperimental and epidemiological data indicate a correlation between exposure to UV radiation and cataract morbidity. UV radiation induced cataract is thought to be evoked by photochemical mechanisms. The present investigation resolves the macroscopical events in the rat lens after a one dose exposure to spectrally and radiometrically well defined UV radiation, as revealed in light‐ and da... hiện toàn bộ
AGE VARIATIONS IN NORMAL HUMAN CONTRAST SENSITIVITY
Acta Ophthalmologica - Tập 57 Số 4 - Trang 679-690 - 1979
Gunilla Derefeldt, Gunnar Lennerstrand, Björn L. Lundh
The visual contrast sensitivity (the reciprocal of contrast threshold) was studied as a function of age. Psychophysical measurements of binocular and monocular contrast thresholds were made for 33 normal observers at spatial frequencies within the range 0.5 to 40 cycles/degree. The observers were divided into three different age groups: young, middle‐aged, and old subjects with the age ranges 6–10... hiện toàn bộ
THE INFLUENCE OF PREGNANCY ON DIABETIC RETINOPATHY WITH SPECIAL REGARD TO THE REVERSIBLE CHANGES SHOWN IN 100 PREGNANCIES
Acta Ophthalmologica - Tập 62 Số 4 - Trang 603-616 - 1984
Vagn Ohrt
A prospective study of the eyes of 75 diabetic women during the course of 100 pregnancies is presented as a contribution to the, as yet, still unresolved question concerning the influence of pregnancy on diabetic retinopathy. Fifty patients in the material had a retinopathy prior to pregnancy, proliferations were present in 2 of them. During the course of the pregnancy, proliferative changes devel... hiện toàn bộ
Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx® flex and comparison with a retrospective study of FS‐laser in situ keratomileusis
Acta Ophthalmologica - Tập 91 Số 4 - Trang 355-362 - 2013
Anders Højslet Vestergaard, Anders Ivarsen, S. Asp, Jesper Hjortdal
Abstract.Purpose:  To present our initial clinical experience with ReLEx® flex (ReLEx) for moderate to high myopia. We compare efficacy, safety and corneal higher‐order aberrations after ReLEx with femtosecond laser in situ keratomileusis (FS‐LASIK).Methods:  Prospective study of ReLEx compared with a retrospective study of FS‐LASIK. ReLEx is a new keratorefractive procedure, where a stromal lenti... hiện toàn bộ
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