Epidemiologic Perspectives & Innovations

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The effects of neighborhood density and street connectivity on walking behavior: the Twin Cities walking study
Epidemiologic Perspectives & Innovations - Tập 4 - Trang 1-9 - 2007
J Michael Oakes, Ann Forsyth, Kathryn H Schmitz
A growing body of health and policy research suggests residential neighborhood density and street connectivity affect walking and total physical activity, both of which are important risk factors for obesity and related chronic diseases. The authors report results from their methodologically novel Twin Cities Walking Study; a multilevel study which examined the relationship between built environme...... hiện toàn bộ
Warning: Anti-tobacco activism may be hazardous to epidemiologic science
Epidemiologic Perspectives & Innovations - - 2007
Carl Phillips
AbstractThis commentary accompanies two articles submitted to Epidemiologic Perspectives & Innovations in response to a call for papers about threats to epidemiology or epidemiologists from organized political interests. Contrary to our expectations, we received no submissions that described threats from industry or government; all we...... hiện toàn bộ
New patient-oriented summary measure of net total gain in certainty for dichotomous diagnostic tests
Epidemiologic Perspectives & Innovations - Tập 3 - Trang 1-9 - 2006
Shai Linn, Peter D Grunau
To introduce a new, patient-oriented predictive index as a measure of gain in certainty. Algebraic equations. A new measure is suggested based on error rates in a patient population. The new Predictive Summary Index (PSI) reflects the true total gain in certainty obtained by performing a diagnostic test based on knowledge of disease prevalence, i.e., the overall additional certainty. We show that ...... hiện toàn bộ
Translational methods in biostatistics: linear mixed effect regression models of alcohol consumption and HIV disease progression over time
Epidemiologic Perspectives & Innovations - Tập 4 Số 1 - 2007
Mariel M. Finucane, Jeffrey H. Samet, Nicholas J. Horton
AbstractLongitudinal studies are helpful in understanding how subtle associations between factors of interest change over time. Our goal is to apply statistical methods which are appropriate for analyzing longitudinal data to a repeated measures epidemiological study as a tutorial in the appropriate use and interpretation of random effects models. To motivate their...... hiện toàn bộ
Generalizability in two clinical trials of Lyme disease
Epidemiologic Perspectives & Innovations - Tập 3 - Trang 1-7 - 2006
Daniel J Cameron
To examine the generalizability of two National Institutes of Health (NIH)-funded double-blind randomized placebo-controlled clinical trials in patients with chronic Lyme disease and to determine whether selection factors resulted in the unfavorable outcomes. Epidemiologic review of the generalizability of two trials conducted by Klempner et al. This paper considers whether the study group was rep...... hiện toàn bộ
Update: Greenland and Robins (1986). Identifiability, exchangeability and epidemiological confounding
Epidemiologic Perspectives & Innovations - Tập 6 - Trang 1-2 - 2009
George Maldonado
We are pleased to publish an update to "Identifiabiliity, exchangeability and epidemiological confounding" (IEEC) by Sander Greenland and James Robins, originally published in 1986 in the International Journal of Epidemiology. This is the first in a series of updates to classic epidemiologic-methods papers that EP&I has commissioned.
Case-case analysis of enteric diseases with routine surveillance data: Potential use and example results
Epidemiologic Perspectives & Innovations - Tập 5 - Trang 1-8 - 2008
Nick Wilson, Michael Baker, Richard Edwards, Greg Simmons
Case-control studies and outbreak investigations are the major epidemiological tools for providing detailed information on enteric disease sources and risk factors, but these investigations can be constrained by cost and logistics. We explored the advantages and disadvantages of comparing risk factors for enteric diseases using the case-case method. The main issues are illustrated with an analysis...... hiện toàn bộ
An easy approach to the Robins-Breslow-Greenland variance estimator
Epidemiologic Perspectives & Innovations - Tập 2 - Trang 1-6 - 2005
Paul Silcocks
The Mantel-Haenszel estimate for the odds ratio (and its logarithm) in stratified case control studies lacked a generally acceptable variance estimate for many years. The Robins-Breslow-Greenland estimate has met this need, but standard textbooks still do not provide an explanation of how it is derived. This article provides an accessible derivation which demonstrates the link between the Robins-B...... hiện toàn bộ
Historical Perspective: S. Leonard Syme's influence on the development of social epidemiology and where we go from there
Epidemiologic Perspectives & Innovations - Tập 2 - Trang 1-5 - 2005
Irene H Yen
This article accompanies Len Syme's "Historical Perspective: The social determinants of disease – some roots of the movement." It describes some of Len's role in the development of social epidemiology through mentoring investigators and influencing training programs. It also discusses some challenges for the field and ways to move forward.
Identifiability, exchangeability and confounding revisited
Epidemiologic Perspectives & Innovations - Tập 6 - Trang 1-9 - 2009
Sander Greenland, James M Robins
In 1986 the International Journal of Epidemiology published "Identifiability, Exchangeability and Epidemiological Confounding". We review the article from the perspective of a quarter century after it was first drafted and relate it to subsequent developments on confounding, ignorability, and collapsibility.
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