Proceedings IEEE International Symposium on Biomedical Imaging
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3D tomographic reconstruction of binary images from cone beam projections: a fast level set approach
- Trang 677-680
This paper addresses 3D tomographic reconstruction of a binary image from a small number of cone-beam projections. Under the binary hypothesis, the object may be conveniently represented by its surfaces, and the reconstruction problem solved using active contour methods. To handle complex topologies, we formalize the problem in the framework of level sets using implicit descriptions of object boun......
#Tomography #Image reconstruction #Level set #Surface reconstruction #Topology #X-ray imaging #Statistical analysis #Integral equations #Active contours #Biological system modeling
Theoretical analysis of blind identification of kinetic parameters in a three compartment model: nonuniqueness problem
- Trang 581-584
Estimation of compartment model parameters can be done in dynamic medical imaging blindly - that is, without an input function. In this work we address the question of uniqueness of blind identification of kinetic parameters for a three compartment model such as is widely used with FDG. We show analytically that if only two regions of interest in the imaged organ are used, the solution is not uniq......
#Kinetic theory #Blood #Positron emission tomography #Equations #Biomedical imaging #Sugar #Noise measurement #Poles and zeros #Physics #Radiology
Hybrid MR/near infrared imaging of the murine brain: optimization of optical fiber arrangement and use of a-priori knowledge
- Trang 74-77
In this work we will present our initial study into the use of hybrid MRI/Near Infrared (NIR) imaging system and the reconstruction algorithm for the murine head. We will show that the arrangement of optical fibers on one side of the head, near the brain, will provide more information about optical changes within the brain. Also, we will show that by the use of a-priori information from MRI and ap......
#Infrared imaging #Optical fibers #Head #Magnetic resonance imaging #Optical imaging #Image reconstruction #Image segmentation #Spatial resolution #Reconstruction algorithms #Tomography
Determining the through-plane resolution of strain-encoded MRI
- Trang 919-922
Strain encoded magnetic resonance elastography (SENC MRE) has been proposed for imaging elastic variation by obtaining images whose intensity directly represents through-plane strain. It is useful for detecting tumors because tumors exhibit different elastic properties than the surrounding tissue. SENC MRE, however, assumes homogeneous tissue elasticity in the through-plane direction, an assumptio......
#Magnetic resonance imaging #Elasticity #Neoplasms #Magnetic field induced strain #Imaging phantoms #Ultrasonic imaging #Frequency #Mechanical factors #Magnetic resonance #Benign tumors
An integrated confocal and magnetic resonance microscope for observing living cells
- Trang 801-804
We have combined a confocal fluorescence optical microscope and a magnetic resonance microscope into one instrument to image simultaneously a living cell system. The high spatial resolution confocal and high spectral resolution magnetic resonance microscope produces a set of closely linked, complementary images. To enhance the value of this image set, we have also developed a statistical method, l......
#Magnetic resonance #Magnetic force microscopy #Optical microscopy #Spatial resolution #Instruments #Image resolution #Predictive models #Fluorescence #Statistical analysis #Calibration
Molecular imaging of biological processes from microPET in mice to PET in patients
- Trang 1-9
This article focuses on bringing together mice to patients with microPET to PET and molecular imaging probes and drugs for molecular diagnostics and molecular therapeutics. In the latter there is a common disease target in which near massless amounts of a molecular imaging probe is used to image the presence and function of the target and then to use the same molecule, or analogs of it, in mass am......
#Molecular imaging #Biological processes #Mice #Positron emission tomography #Cardiac disease #Cardiovascular diseases #Probes #Systems biology #Cells (biology) #Drugs
Three dimensional functional cartography of the human basal ganglia by registration of optical and histological serial sections
- Trang 329-332
In functional neurosurgery, there is a need for accurate localisation of the functional targets. One example is given by Parkinson's disease. The surgical intervention is based on the introduction of electrodes in the subthalamic nucleus. This nucleus is targeted on pre-operative stereotactic MR acquisitions. But MR imaging of the basal ganglia is intrinsically limited, first by image resolution, ......
#Humans #Basal ganglia #Optical imaging #Image reconstruction #Neurosurgery #Parkinson's disease #Surgery #Electrodes #Image resolution #Anatomy
Microsphere as a contrast agent/gene vector in ultrasound imaging-based vascular gene delivery
- Trang 989-992
The purpose of this study was to test the feasibility of using a novel biodegradable microsphere as a contrast agent/gene vector in ultrasound imaging-based vascular gene delivery. We first encapsulated green fluorescent protein (GFP) gene into the microspheres and validated the echogenic property of GFP-plasmid/microspheres with intramuscular injection. Then, the GFP-plasmid/microspheres were tra......
#Ultrasonic imaging #Arteries #Catheters #Biodegradable materials #Monitoring #Gene expression #Immune system #Gene therapy #Polymers #Fluorescence
Positron emission tomography (PET): a powerful molecular imaging technique
- Trang 811-814
Non-invasive, in vivo molecular imaging will assume an increasing role in the diagnosis and management of patients with cancer in the future. During the past decade, there has been a revolution in our basic understanding of human disease and cancer in particular. This has been made possible from the rapid development of basic molecular techniques. Associated with the developments in molecular biol......
#Positron emission tomography #Molecular imaging #Cancer #Neoplasms #Medical treatment #Diseases #In vivo #Humans #Biology #Spectroscopy
Depth-of-interaction effects in columnar phosphors for exponential X-ray absorption
- Trang 557-560
The depth-dependent blur of phosphor screens have been studied using analytical and numerical methods by a number of investigators. We present an analysis of the effect of depth-of-interaction on the modulation transfer function of columnar phosphor screens. We extend our previously reported results of single X-ray interactions to the study of X-ray beams that exponentially deposit energy in the p......
#Phosphors #Electromagnetic wave absorption #X-ray imaging #Optical sensors #Sensor arrays #Optical refraction #Optical scattering #Optoelectronic and photonic sensors #Optical detectors #X-ray detection