p73 Induces Apoptosis via PUMA Transactivation and Bax Mitochondrial Translocation

Journal of Biological Chemistry - Tập 279 Số 9 - Trang 8076-8083 - 2004
Gerry Melino1,2, Francesca Bernassola1, Marco Ranalli1, Karen S. Yee3, Wei Zong4, Marco Corazzari1, Richard A. Knight5, Douglas R. Green6, Craig B. Thompson4, Karen H. Vousden3
1Biochemistry Laboratory, Instituto Dermopatico Dell'Immacolata-Istituto di Ricovero e Cura a Carattere Scientifico, Department of Experimental Medicine and Biochemical Sciences, University of Rome “Tor Vergata,” 00133 Rome, Italy
2Medical Research Council Toxicology Unit, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom
3Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, United Kingdom
4Abramson Family Cancer Research Institute, Department of Cancer Biology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104
5Department of Cystic Fibrosis, National Heart and Lung Institute, Imperial College, London, SW3 6LR, United Kingdom
6Division of Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California 92037

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