WAF1, a potential mediator of p53 tumor suppression

Cell - Tập 75 Số 4 - Trang 817-825 - 1993
Wafik S. El‐Deiry1, Takashi Tokino, Victor E. Velculescu, Daniel B. Levy, Ramon Parsons, Jeffrey M. Trent, David Pei‐Cheng Lin, W E Mercer, K W Kinzler, B Vogelstein
1Oncology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21231

Tóm tắt

Từ khóa


Tài liệu tham khảo

Baker, 1989, Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas, Science, 244, 217, 10.1126/science.2649981

Baker, 1990, Suppression of human colorectal carcinoma cell growth by wild-type p53, Science, 249, 912, 10.1126/science.2144057

Barak, 1993, Mdm-2 expression is induced by wild-type p53 activity, EMBO, 12, 461, 10.1002/j.1460-2075.1993.tb05678.x

Berg, 1986, Potential metal-binding domains in nucleic acid binding proteins, Science, 232, 485, 10.1126/science.2421409

Clarke, 1993, Thymocyte apoptosis induced by p53-dependent and independent pathways, Nature, 362, 849, 10.1038/362849a0

Cliby, 1993, Human epithelial ovarian cancer allelotype, Cancer Res., 53, 2393

Davis, 1986

El-Deiry, 1991, High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer, 88, 3470

El-Deiry, 1992, Definition of a consensus binding site for p53, Nature Genet., 1, 45, 10.1038/ng0492-45

Elledge, 1991, λYES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations, 88, 1731

Fakharzadeh, 1991, Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line, EMBO J., 10, 1565, 10.1002/j.1460-2075.1991.tb07676.x

Farmer, 1992, Wild-type p53 activates transcription in vitro, Nature, 358, 83, 10.1038/358083a0

Feinberg, 1983, A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity, Anal. Biochem., 132, 6, 10.1016/0003-2697(83)90418-9

Fields, 1990, Presence of a potent transcription activating sequence in the p53 protein, Science, 249, 1046, 10.1126/science.2144363

Finlay, 1993, The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth, Mol. Cell. Biol., 13, 301

Funk, 1992, A transcriptionally active DNA-binding site for human p53 protein complexes, Mol. Cell. Biol., 12, 2866

Ginsberg, 1991, Wild-type p53 can down-modulate the activity of various promoters, 88, 9979

Halevy, 1991, Frequent p53 mutations in chemically induced murine fibrosarcoma, Oncogene, 6, 1593

Hampson, 1992, Chemical cross linking subtraction (CCLS): a new method for the generation of subtractive hybridisation probes, Nucl. Acids Res., 20, 2899, 10.1093/nar/20.11.2899

Harper, 1993, The p21 cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases, Cell, 75

Hollstein, 1991, p53 mutation in human cancers, Science, 253, 49, 10.1126/science.1905840

Kastan, 1991, Participation of p53 protein in the cellular response to DNA damage, Cancer Res., 53, 6304

Kastan, 1992, A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia, Cell, 71, 587, 10.1016/0092-8674(92)90593-2

Kern, 1991, Identification of p53 as a sequence specific DNA binding protein, Science, 252, 1707, 10.1126/science.2047879

Kern, 1992, Oncogenic forms of p53 inhibit p53-regulated gene expression, Science, 256, 827, 10.1126/science.256.5058.827

Kinzler, 1989, Whole genome PCR: application to the identification of sequences bound by gene regulatory proteins, Nucl. Acids Res., 17, 3645, 10.1093/nar/17.10.3645

Kley, 1992, Repression of the basal c-fos promoter by wild-type p53, Nucl. Acids Res., 20, 4083, 10.1093/nar/20.15.4083

Lane, 1992, p53, guardian of the genome, Nature, 358, 15, 10.1038/358015a0

Lin, 1992, Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1-phase, 89, 9210

Liu, 1993, The p53 activation domain binds the TATA box-binding polypeptide in holo-TFIID, and a neighboring p53 domain inhibits transcription, Mol. Cell. Biol., 13, 3291

Livingstone, 1992, Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53, Cell, 70, 923, 10.1016/0092-8674(92)90243-6

Lowe, 1993, p53 is required for radiation-induced apoptosis in mouse thymocytes, Nature, 362, 847, 10.1038/362847a0

Lukeis, 1990, Cytogenetics of non-small cell lung cancer: analysis of consistent non-random abnormalities, Gen. Chrom. Cancer, 2, 116, 10.1002/gcc.2870020207

Mack, 1993, Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53, Nature, 363, 281, 10.1038/363281a0

Maltzman, 1984, UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells, Mol. Cell. Biol., 4, 1689

Martin, 1993, p53 binds to the TATA-binding protein-TATA complex, J. Biol. Chem., 268, 13062, 10.1016/S0021-9258(19)38619-3

Meltzer, 1992, Micro-FISH: a novel strategy to identify cryptic chromosomal rearrangements, Nature Genet., 1, 24, 10.1038/ng0492-24

Mercer, 1992, Cell cycle regulation and the p53 tumor suppressor protein, Crit. Rev. Eucar. Gene Exp., 2, 251

Mercer, 1990, Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53, 87, 6166

Michalovitz, 1990, Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53, Cell, 62, 671, 10.1016/0092-8674(90)90113-S

Mietz, 1992, The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein, EMBO J., 11, 5013, 10.1002/j.1460-2075.1992.tb05608.x

Momand, 1992, The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation, Cell, 69, 1237, 10.1016/0092-8674(92)90644-R

Morita, 1991, Allelotype of renal cell carcinoma, Cancer Res., 51, 820

Munholland, 1992, Cell specificity of transcription regulation by papovavirus T antigens and DNA replication, EMBO J., 11, 177, 10.1002/j.1460-2075.1992.tb05040.x

Nigro, 1992, Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae, Mol. Cell. Biol., 12, 1357

Oliner, 1993, Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53, Nature, 362, 857, 10.1038/362857a0

Oren, 1992, p53: the ultimate tumor suppressor gene?, FASEB J., 6, 3169, 10.1096/fasebj.6.13.1397838

Perry, 1993, Tumor-suppressor p53 and the cell cycle, Curr. Opin. Genet. Dev., 3, 50, 10.1016/S0959-437X(05)80340-5

Prives, 1993, The p53 tumor suppressor protein, Genes Dev., 7, 529, 10.1101/gad.7.4.529

Ragimov, 1993, Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif, Oncogene, 8, 1183

Raycroft, 1990, Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene, Science, 249, 1049, 10.1126/science.2144364

Robbins, 1991, Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence, Cell, 64, 615, 10.1016/0092-8674(91)90245-T

Santhanam, 1991, Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product, 88, 7605

Sato, 1991, Allelotype of human ovarian cancer, Cancer Res., 51, 5118

Scharer, 1992, Mammalian p53 can function as a transcription factor in yeast, Nucl. Acids Res., 20, 1539, 10.1093/nar/20.7.1539

Seto, 1992, Wild-type p53 binds to the TATA-binding protein and represses transcription, 89, 12028

Shaw, 1992, Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line, 89, 4495

Sherley, 1991, Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration, J. Biol. Chem., 266, 24815, 10.1016/S0021-9258(18)54302-7

Smith, 1993, The APC gene product in normal and tumor cells, 90, 2846

Solomon, 1991, Chromosome aberrations and cancer, Science, 254, 1153, 10.1126/science.1957167

Sterner, 1993, In vivo recognition of a vertebrate mini-exon as an exon-intron-exon unit, Mol. Cell. Biol., 13, 2677

Truant, 1993, Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein, J. Biol. Chem., 268, 2284, 10.1016/S0021-9258(18)53769-8

Ullrich, 1992, Human wild-type p53 adopts a unique conformation and phosphorylation state in vivo during growth arrest of glioblastoma cells, Oncogene, 7, 1635

Vogelstein, 1992, p53 function and dysfunction, Cell, 70, 523, 10.1016/0092-8674(92)90421-8

Vogelstein, 1989, Allelotype of colorectal carcinomas, Science, 244, 207, 10.1126/science.2565047

Weintraub, 1991, The MCK enhancer contains a. p53 responsive element, 88, 4570

Wilkinson, 1992, Constitutive and enhanced expression from the CMV major IE promoter in a defective adenovirus vector, Nucl. Acids Res., 20, 2233, 10.1093/nar/20.9.2233

Wilson, 1991, Identification of the DNA binding site for NGFI-B by genetic selection in yeast, Science, 252, 1296, 10.1126/science.1925541

Wu, 1993, The p53-mdm-2 autoregulatory feedback loop, Genes Dev., 7, 1126, 10.1101/gad.7.7a.1126

Yin, 1992, Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles, Cell, 70, 937, 10.1016/0092-8674(92)90244-7

Zambetti, 1992, Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element, Genes Dev., 6, 1143, 10.1101/gad.6.7.1143

Zauberman, 1993, Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53-MDM2 complexes, EMBO J., 12, 2799, 10.1002/j.1460-2075.1993.tb05941.x

Zhan, 1993, Induction of cellular p53 activity by DNA-damaging agents and growth arrest, Mol. Cell. Biol., 13, 4242