Vasopressin and Aquaporin 2 in Clinical Disorders of Water Homeostasis

Birnbaumer, 1992, Molecular cloning of the receptor for human antidiuretic hormone, Nature, 357, 333, 10.1038/357333a0

Sands, 2006, Nephrogenic diabetes insipidus, Ann Intern Med, 144, 186, 10.7326/0003-4819-144-3-200602070-00007

Wade, 1981, ADH action: evidence for a membrane shuttle mechanism, Ann N Y Acad Sci, 372, 106, 10.1111/j.1749-6632.1981.tb15464.x

Agre, 1993, Aquaporin CHIP the archetypal molecular water channel, Am J Physiol Renal Fluid Electrolyte Physiol, 265, F463, 10.1152/ajprenal.1993.265.4.F463

Fushimi, 1993, Cloning and expression of apical membrane water channel of rat kidney collecting tubule, Nature, 361, 549, 10.1038/361549a0

Nielsen, 2002, Aquaporins in the kidney: from molecules to medicine, Physiol Rev, 82, 205, 10.1152/physrev.00024.2001

Bichet, 2006, Lithium, cyclic AMP signaling, A-kinase anchoring proteins, and aquaporin-2, J Am Soc Nephrol, 17, 920, 10.1681/ASN.2006020135

DiGiovanni, 1994, Regulation of collecting duct water channel expression by vasopressin in Brattleboro rats, Proc Natl Acad Sci U S A, 91, 8984, 10.1073/pnas.91.19.8984

Wade, 1994, Long-term regulation of collecting duct water permeability: freeze-fracture analysis of isolated perfused tubules, Am J Physiol Renal Fluid Electrolyte Physiol, 166, F723, 10.1152/ajprenal.1994.266.5.F723

Yamamura, 1992, Characterization of a novel aquaretic agent, OPC-31260, as an orally effective, nonpeptide vasopressin V2 receptor antagonist, Br J Pharmacol, 105, 787, 10.1111/j.1476-5381.1992.tb09058.x

Schrier, 2007, The sea within us: disorders of body water homeostasis, Curr Opin Invest Drugs, 8, 304

Hoorn, 2006, Development of severe hyponatraemia in hospitalized patients: treatment-related risk factors and inadequate management, Nephrol Dial Transplant, 21, 70, 10.1093/ndt/gfi082

Schrier, 2006, Body water homeostasis: clinical disorders of urinary dilution and concentration, J Am Soc Nephrol, 17, 1820, 10.1681/ASN.2006030240

Lee, 1986, Prognostic importance of serum concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure, Circulation, 73, 257, 10.1161/01.CIR.73.2.257

Schrier, 1999, Hormones and hemodynamics in heart failure, N Engl J Med, 341, 577, 10.1056/NEJM199908193410806

Szatalowicz, 1981, Radioimmunoassay of plasma arginine vasopressin in hyponatremic patients with congestive heart failure, N Engl J Med, 305, 263, 10.1056/NEJM198107303050506

Xu, 1997, Upregulation of aquaporin-2 water channel expression in chronic heart failure, J Clin Invest, 99, 1500, 10.1172/JCI119312

Nielsen, 1997, Congestive heart failure in rats in associated with increased expression and targeting of aquaporin-2 water channel in collecting duct, Proc Natl Acad Sci U S A, 94, 5450, 10.1073/pnas.94.10.5450

Gheorghiade, 2004, Effects of tolvaptan, a vasopressin antagonist, in patients hospitalized with worsening heart failure: a randomized controlled trial, JAMA, 291, 1963, 10.1001/jama.291.16.1963

Abraham, 2006, Aquaretic effect of lixivaptan, an oral non-peptide, selective V2 receptor vasopressin antagonist, in the New York Heart Association functional class II and III chronic heart failure patients, J Am Coll Cardiol, 47, 1615, 10.1016/j.jacc.2005.11.071

Schrier, 2006, Tolvaptan, a selective oral vasopressin V2-receptor antagonist, for hyponatremia, N Engl J Med, 355, 2099, 10.1056/NEJMoa065181

Saito, 1997, Urinary excretion of aquaporin-2 in the diagnosis of central diabetes insipidus, J Clin Endocrinol Metab, 82, 1823, 10.1210/jc.82.6.1823

Martin, 1999, Selective V2 receptor vasopressin antagonism decreases urinary aquaporin-2 excretion in patients with chronic heart failure, J Am Soc Nephrol, 10, 2165, 10.1681/ASN.V10102165

Gheorghiade, 2007, Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan (EVEREST) Investigators, JAMA, 297, 1332, 10.1001/jama.297.12.1332

Konstam, 2007, Effects of oral tolvaptan in patients hospitalized for worsening heart failure, JAMA, 297, 1319, 10.1001/jama.297.12.1319

Schrier, 1990, Body fluid volume regulation in health and disease: a unifying hypothesis, Ann Intern Med, 113, 155, 10.7326/0003-4819-113-2-155

Schrier, 1988, Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis, Hepatology, 8, 1151, 10.1002/hep.1840080532

Schrier, 2007, Decreased effective blood volume in edematous disorders: what does this mean?, J Am Soc Nephrol, 18, 2028, 10.1681/ASN.2006111302

Gines, 1993, Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites, Gastroenterology, 105, 229, 10.1016/0016-5085(93)90031-7

Bichet, 1982, Role of vasopressin in abnormal water excretion in cirrhotic patients, Ann Intern Med, 96, 413, 10.7326/0003-4819-96-4-413

Inoue, 1998, Therapeutic and diagnostic potential of a vasopressin-2 antagonist for impaired water handling in cirrhosis, Clin Pharmacol Ther, 63, 561, 10.1016/S0009-9236(98)90107-2

Ivarsen, 2003, Increased urinary excretion of aquaporin 2 in patients with liver cirrhosis, Gut, 52, 1194, 10.1136/gut.52.8.1194

Gerbes, 2003, Therapy of hyponatremia in cirrhosis with a vasopressin receptor antagonist: a randomized double-blind multicenter trial, Gastroenterology, 124, 933, 10.1053/gast.2003.50143

Briner, 2007, Hypertension and pregnancy, 1326

Chapman, 1998, Temporal relationships between hormonal and hemodynamic changes in early human pregnancy, Kidney Int, 54, 2056, 10.1046/j.1523-1755.1998.00217.x

Schrier, 1991, Peripheral arterial vasodilation hypothesis of sodium and water retention in pregnancy: implications for pathogenesis of preeclampsia-eclampsia state, Obstet Gynecol, 77, 632

Ohara, 1998, Upregulation of aquaporin 2 water channel expression in pregnant rats, J Clin Invest, 101, 1076, 10.1172/JCI649

Martin, 1998, Nitric oxide as a mediator of hemodynamic abnormalities and sodium and water retention in cirrhosis, N Engl J Med, 33, 533, 10.1056/NEJM199808203390807

Cadnapaphornchai, 2001, Chronic NOS inhibition reverses systemic vasodilation and glomerular hyperfiltration in pregnancy, Am J Physiol Renal Physiol, 280, F592, 10.1152/ajprenal.2001.280.4.F592

Potter, 1964, Water retention due to oxytocin, Obstet Gynecol, 23, 699

Lyness, 1985, Antidiuretic effects of oxytocin in the Brattleboro rat, Experientia, 41, 1444, 10.1007/BF01950026

Li, 2008, Effect of oxytocin on water channel expression and trafficking in Brattleboro rats: role of V2 receptor, J Am Soc Nephrol, 19, 225, 10.1681/ASN.2007010029

Skowsky, 1978, The role of vasopressin in the impaired water excretion of myxedema, Am J Med, 64, 613, 10.1016/0002-9343(78)90581-8

Chen, 2005, Nonosmotic release of vasopressin and renal aquaporins in impaired urinary dilution in hypothyroidism, Am J Physiol Renal Physiol, 289, F672, 10.1152/ajprenal.00384.2004

Chen, 2005, Molecular mechanisms of impaired urinary concentrating ability in glucocorticoid-deficient rats, J Am Soc Nephrol, 16, 2864, 10.1681/ASN.2004110944

Evered, 1972, Primary polydipsia in thyrotoxicosis, Metabolism, 21, 393, 10.1016/0026-0495(72)90052-2

Wang, 2007, Polyuria of thyrotoxicosis: Downregulation of aquaporin water channels and increased solute excretion, Kidney Int, 72, 1088, 10.1038/sj.ki.5002475

Schrier, 1971, Tubular reabsorption of sodium ion: influence of factors other than aldosterone and glomerular filtration rate 1, N Engl J Med, 285, 1231, 10.1056/NEJM197111252852205

Klein, 2006, Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension, Am J Physiol Renal Physiol, 291, F952, 10.1152/ajprenal.00173.2006

Ishikawa, 1982, Effect of arginine vasopressin antagonist on renal water excretion in glucocorticoid and mineralocorticoid deficient rats, Kidney Int, 22, 587, 10.1038/ki.1982.216

Ufferman, 1972, Importance of sodium intake and mineralocorticoid hormone in the impaired water excretion in adrenal insufficiency, J Clin Invest, 57, 1639, 10.1172/JCI106965

Ohara, 2002, Effect of mineralocorticoid deficiency on ion and urea transporters and aquaporin water channels in the rat, Biochem Biophy Res Commun, 299, 285, 10.1016/S0006-291X(02)02634-7

Chen, 2005, Molecular mechanisms of impaired urinary concentrating ability in glucocorticoid-deficient rats, J Am Soc Nephrol, 16, 2864, 10.1681/ASN.2004110944

Agus, 1971, Role of antidiuretic hormone in the abnormal water diuresis of anterior hypopituitarism in man, J Clin Invest, 50, 1478, 10.1172/JCI106633

Kim, 2001, Role of glucocorticoid hormones in arginine vasopressin gene regulation, Biochem Biophys Res Commun, 289, 1252, 10.1006/bbrc.2001.6114

Wang, 2006, Molecular analysis of impaired urinary diluting capacity in glucocorticoid deficiency, Am J Physiol Renal Physiol, 290, F1135, 10.1152/ajprenal.00356.2005