Use of phytohemagglutinin response to determine the extent that somatic cell mutation accounts for 6-thioguanine resistance of human blood mononuclear cells

Albertini, 1979, Direct mutagenicity testing with peripheral blood lymphocytes, 359 Albertini, 1982, Studies with T-lymphocytes: an approach to human mutagenicity monitoring, 393 Albertini, 1981, Human somatic cell mutation: In vivo variant lymphocyte frequencies as determined by 6-thioguanine resistance, 235 Albertini, 1982, T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood, 79, 6617 Amneus, 1982, Human lymphocytes resistant to 6-thioguanine: restrictions in the use of a test for somatic mutations arising in vivo studied by flow-cytometric enrichment of resistant cell nuclei, Mutation Res., 106, 163, 10.1016/0027-5107(82)90199-3 Amneus, 1984, Resistance to 6-thioguanine in spontaneously cycling and in mitogen stimulated human peripheral lymphocytes, Mutation Res., 139, 41, 10.1016/0165-7992(84)90120-9 Bond, 1959, Proliferative potentials of bone marrow and blood cells studied by in vitro uptake of H3-thymidine, Acta Haemat., 21, 1, 10.1159/000205651 Boyum, 1968, Isolation of mononuclear cells and granulocytes from human blood, Scand. J. Clin. Lab. Invest., 97, 77 Cox, 1978, Do radiation-induced thioguanine-resistant mutants of cultured mammalian cells arise by HGPRT gene mutation or X-chromosome rearrangement?, Nature (London), 264, 629, 10.1038/276629a0 DeMars, 1981, Mutation rates of human somatic cells cultivated in vitro, 209 Dempsey, 1983, Evidence that thioguanine-resistant lymphocytes detected by autoradiography are mutant cells, Mutation Res., 119, 203, 10.1016/0165-7992(83)90130-6 Evans, 1981, Induction of 8-azaguanine resistance and sister chromatid exchange in human lymphocytes exposed to mitomycin C and X rays in vitro, Nature (London), 292, 601, 10.1038/292601a0 Morley, 1982, Enumeration of thioguanine-resistant lymphocytes using autoradiography, Mutation Res., 95, 363, 10.1016/0027-5107(82)90271-8 Morley, 1983, Measurement of in vivo mutations in human lymphocytes, Nature (London), 302, 155, 10.1038/302155a0 Nusbacher, 1977, Plateletpheresis using the Haemonetics Model 30 cell separator, Vox Sang., 33, 9, 10.1111/j.1423-0410.1977.tb02230.x Strauss, 1982, Direct mutagenicity testing: the development of a clonal assay to detect and quantitate mutant lymphocytes arising in vivo, 423 Strauss, 1977, 6-Thioguanine resistant lymphocytes in human peripheral blood, 327 Strauss, 1979, Enumeration of 6-thioguanine-resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo, Mutation Res., 61, 353, 10.1016/0027-5107(79)90140-4 Thompson, 1973, Isolation of mutants of cultured mammalian cells, Methods Cell Biol., 16, 209, 10.1016/S0091-679X(08)60052-7 Vijayalaxmi, 1984, Measurement of spontaneous and X-irradiation-induced 6-thioguanine-resistant human blood lymphocytes using a T-cell cloning technique, Mutation Res., 125, 87, 10.1016/0027-5107(84)90035-6 Vijayalaxmi, 1983, Bloom's syndrome: Evidence for an increased mutation frequency in vivo, Science, 221, 851, 10.1126/science.6879180