Unilateral optic disc edema in a patient with acute lymphocytic leukemia

Annals of Ophthalmology - Tập 37 - Trang 303-305 - 2005
Ihsan Çaça1, Kaan Ünlü1, Seyhmus Ari1, Ahmet Dirier2
1Department of Ophthalmology, Dicle University, Faculty of Medicine,Diyarbakir, Turkey
2Department of Radiation Oncology, Dicle University Faculty of Medicine, Diyarbakir, Turkey

Tóm tắt

A young male complained of acute left-eye visual loss. The right eye was normal. Only hand motions were seen with the left. The dilated fundus showed mild optic disk elevation, blurred margins, tortuous vessels, retinal vascular sheathing, and flame-shaped hemorrhages. Laboratory exam revealed acute lymphocytic leukemia. Following chemotherapy and radiotherapy, disk swelling and retinal changes resolved and visual acuity improved.

Tài liệu tham khảo

Charif Chefchaouni M, Belmekki M, Hajji Z, and et al. Ophthalmic manifestations of acute leukemia. J Fr Ophthalmol 2002;25:62–66.

Mayo GL, Carter JE, McKinnon SJ. Bilateral optic disk edema and blindness as initial presentation of acute lymphocytic leukemia. Am J Ophthalmol 2002;134:141–142.

Kaikov Y. Optic nerve head infiltration in acute leukemia in children: an indication for emergency optic nerve head radiation therapy. Med Pediatr Oncol 1996;26:101–104.

Pierro L, Brancato R, Zaganelli E, Guarisco L, Lanzetta P. Ocular involvement in acute lymphoblastic leukemia: an echographic study. Int Ophthalmol. 1992;16:159–162.

Stammen J, Unsold R, Arendt G, and et al. Etiology and pathogenetic mechanisms of optic disc swelling with visual loss. An interdisciplinary prospective pilot study of 102 cases. Ophthalmologica 1999;213:40–47.

Soylu M, Tanyeli A, Ozdemir N, Eroglu A, Ersoz TR. Ocular involvement in childhood leukemias. Turk J Pediatr 1994;36:35–41.

Rosenthal AR. Ocular manifestations of leukemia. A review. Ophthalmology 1983;90:899–905.

Ohkoshi K, Tsiaras WG. Prognostic importance of ophthalmic manifestations in childhood leukemia. Br J Ophthalmol 1992;76: 651–655.

Abdul-Rahim AS, Brown SM, Shami MJ. Bilateral retinal hemorrhages in an 18-year-old woman. Surv Ophthalmol 2002;47:590–593.

Holt JM, Gordon-Smith EC. Retinal abnormalities in diseases of the blood. Br J Ophthalmol 1969;53:145–160.

Reddy SC, Quah SH, Low HC, Jackson N. Prognostic significance of retinopathy at presentation in adult acute leukemia. Ann Hematol 1998;76:15–18.

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Thông tin xuất bản

Annals of Ophthalmology

Tập 37

303-305

Thông tin tác giả