Ocular involvement in acute lymphoblastic leukemia: an echographic study

International Ophthalmology - Tập 16 - Trang 159-162 - 1992
L. Pierro1, R. Brancato1, E. Zaganelli1, L. Guarisco1, P. Lanzetta1
1Department of Ophthalmology, University of Milan, Scientific Institute HS Raffaele, Milan, Italy

Tóm tắt

We report a case of acute lymphoblastic leukemia (ALL) with ocular involvement in which bilateral swelling of the optic disk head was noticed. Massive direct infiltration of the optic nerve head by leukemic cells can give rise to a clinical picture identical to that of a true papilledema. Ocular echography allowed a better and more complete interpretation of the optic disk involvement. No echographic description of a leukemic infiltration of the optic nerve head has been reported previously.

Tài liệu tham khảo

Shields JA. Diagnosis and management of intraocular tumors. St Louis: The CV Mosby Co, 1983: 619–48. Leonardy NJ, Rupani M, Dent GD, Klinthworth GK. Analysis of 135 autopsy eyes for ocular involvement in leukemia. Am J Ophthalmol 1990; 109: 436–44. Culver Boldt H, Schachat AP. Ophthalmic manifestations of leukemia. Atti del Congresso: International Symposium on Intraocular Tumors; Firenze 1990. Medical Books (ed), 1991: 341–3. Rosenthal AR. Ocular manifestations of leukemia. Ophthalmology 1983; 90: 899. Guyer DR, Schachat AP, Vitale S, Markowitz JA, Braine H, Burke PJ, et al. Leukemic retinopathy: relationship between fundus lesions and hematologic parameters at diagnosis. Ophthalmology 1989; 96: 860. Kincaid MC, Green WR. Ocular and orbital involvement in leukemia. Surv Ophthalmol 1983; 4: 211–32. Nikaido H, Mishima H, Ono N, Choshi K, Dohy H. Leukemic involvement of the optic disc nerve. Am J Ophthalmol 1988; 105: 294–8. Cennamo G, Gangemi H, Stella L, Falivene R. Correla-ione fra la pressione endocranica ed il diametro del nervo ottico: studio ecografico. Clin Ocul e Pat Ocul 1984; 5(Suppl): 39–41. Mazzeo V. Tumori linfatici e leucemie. In: Ecografia delPapparato oculare (ed) Fogliazza 1987: 203-5. Poujol J, Le Roy M. Echographic modifications of the choroid in its tumors and pseudotumors. Doc Ophthalmol Proc Ser 1983; 38: 57–62.