Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

New England Journal of Medicine - Tập 349 Số 3 - Trang 247-257 - 2003
Christine Ribic1, Daniel J. Sargent2, Malcolm J. Moore3,4, Stephen N. Thibodeau5, Amy J. French5, Richard M. Goldberg6, Stanley R. Hamilton7,8, Pierre Laurent‐Puig9, Robert Gryfe1,10, Lois E. Shepherd3, Dongsheng Tu3, Mark Redston11, Steven Gallinger1,3,4,10
1Centre for Cancer Genetics, Samuel Lunenfeld Research Institute
2Division of Biostatistics.
3Clinical Trials Group, National Cancer Institute of Canada, Queen's University, Kingston, Ont.
4Department of Medicine and Surgery, Princess Margaret Hospital
5Department of Laboratory Medicine and Pathology
6Division of Medical Oncology
7Eastern Cooperative Oncology Group, Brookline, Mass.
8M.D. Anderson Cancer Center, Houston
9Fédération Francophone de Cancérologie Digestive, Paris
10Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto
11Brigham and Women's Hospital, Boston

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