Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

Immunity - Tập 39 Số 2 - Trang 372-385 - 2013
Teresa Zelante1, Rossana G. Iannitti1, Cristina Cunha1, Antonella De Luca1, Gloria Giovannini1, Giuseppe Pieraccini2, Riccardo Zecchi2, Carmen D’Angelo1, Cristina Massi-Benedetti1, Francesca Fallarino1, Agostinho Carvalho1, Paolo Puccetti1, Luigina Romani1
1Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia 06132, Italy
2Mass Spectrometry Centre (CISM) of the University of Florence, Florence 50139, Italy

Tóm tắt

Từ khóa


Tài liệu tham khảo

Atarashi, 2011, Induction of colonic regulatory T cells by indigenous Clostridium species, Science, 331, 337, 10.1126/science.1198469

Balish, 1993, Mucosal and disseminated candidiasis in gnotobiotic SCID mice, J. Med. Vet. Mycol., 31, 143, 10.1080/02681219380000161

Boekhorst, 2004, The complete genomes of Lactobacillus plantarum and Lactobacillus johnsonii reveal extensive differences in chromosome organization and gene content, Microbiology, 150, 3601, 10.1099/mic.0.27392-0

Brown, 1978, Gastrointestinal microecology of BALB/c nude mice, Appl. Environ. Microbiol., 36, 144, 10.1128/AEM.36.1.144-159.1978

Chung, 2011, Possible roles of excess tryptophan metabolites in cancer, Environ. Mol. Mutagen., 52, 81, 10.1002/em.20588

Crellin, 2010, Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2, Immunity, 33, 752, 10.1016/j.immuni.2010.10.012

Dai, 2010, Indoleamine 2,3-dioxygenase tissue distribution and cellular localization in mice: implications for its biological functions, J. Histochem. Cytochem., 58, 17, 10.1369/jhc.2009.953604

De Luca, 2010, IL-22 defines a novel immune pathway of antifungal resistance, Mucosal Immunol., 3, 361, 10.1038/mi.2010.22

Denou, 2007, Gene expression of commensal Lactobacillus johnsonii strain NCC533 during in vitro growth and in the murine gut, J. Bacteriol., 189, 8109, 10.1128/JB.00991-07

Denou, 2008, Identification of genes associated with the long-gut-persistence phenotype of the probiotic Lactobacillus johnsonii strain NCC533 using a combination of genomics and transcriptome analysis, J. Bacteriol., 190, 3161, 10.1128/JB.01637-07

Falagas, 2006, Probiotics for prevention of recurrent vulvovaginal candidiasis: a review, J. Antimicrob. Chemother., 58, 266, 10.1093/jac/dkl246

Fallarino, 2006, The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cells, J. Immunol., 176, 6752, 10.4049/jimmunol.176.11.6752

Frese, 2011, The evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri, PLoS Genet., 7, e1001314, 10.1371/journal.pgen.1001314

Fuentes, 2008, A strain of Lactobacillus plantarum affects segmented filamentous bacteria in the intestine of immunosuppressed mice, FEMS Microbiol. Ecol., 63, 65, 10.1111/j.1574-6941.2007.00411.x

Gummallaa, 1999, Tryptophan catabolism by Lactobacillus casei and Lactobacillus helveticus cheese flavor adjuncts, J. Dairy Sci., 82, 2070, 10.3168/jds.S0022-0302(99)75448-2

Hashimoto, 2012, ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation, Nature, 487, 477, 10.1038/nature11228

2012, Structure, function and diversity of the healthy human microbiome, Nature, 486, 207, 10.1038/nature11234

Iliev, 2012, Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis, Science, 336, 1314, 10.1126/science.1221789

Ivanov, 2009, Induction of intestinal Th17 cells by segmented filamentous bacteria, Cell, 139, 485, 10.1016/j.cell.2009.09.033

Jenq, 2012, Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation, J. Exp. Med., 209, 903, 10.1084/jem.20112408

Karczewska, 2009, Assessment of co-existence of Helicobacter pylori and Candida fungi in diseases of the upper gastrointestinal tract, J. Physiol. Pharmacol., 60, 33

Lamont, 2011, The vaginal microbiome: new information about genital tract flora using molecular based techniques, BJOG, 118, 533, 10.1111/j.1471-0528.2010.02840.x

Lee, 2012, AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch, Nat. Immunol., 13, 144, 10.1038/ni.2187

Li, 2011, Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation, Cell, 147, 629, 10.1016/j.cell.2011.09.025

Lutgendorff, 2008, The role of microbiota and probiotics in stress-induced gastro-intestinal damage, Curr. Mol. Med., 8, 282, 10.2174/156652408784533779

Manzoni, 2006, Oral supplementation with Lactobacillus casei subspecies rhamnosus prevents enteric colonization by Candida species in preterm neonates: a randomized study, Clin. Infect. Dis., 42, 1735, 10.1086/504324

Mason, 2012, Interplay between the gastric bacterial microbiota and Candida albicans during postantibiotic recolonization and gastritis, Infect. Immun., 80, 150, 10.1128/IAI.05162-11

Mezrich, 2010, An interaction between kynurenine and the aryl hydrocarbon receptor can generate regulatory T cells, J. Immunol., 185, 3190, 10.4049/jimmunol.0903670

Monteleone, 2011, Aryl hydrocarbon receptor-induced signals up-regulate IL-22 production and inhibit inflammation in the gastrointestinal tract, Gastroenterology, 141, 237, 10.1053/j.gastro.2011.04.007

Noverr, 2004, Regulation of Candida albicans morphogenesis by fatty acid metabolites, Infect. Immun., 72, 6206, 10.1128/IAI.72.11.6206-6210.2004

Opitz, 2011, An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor, Nature, 478, 197, 10.1038/nature10491

Peña, 2004, Genotypic and phenotypic studies of murine intestinal lactobacilli: species differences in mice with and without colitis, Appl. Environ. Microbiol., 70, 558, 10.1128/AEM.70.1.558-568.2004

Pridmore, 2004, The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533, Proc. Natl. Acad. Sci. USA, 101, 2512, 10.1073/pnas.0307327101

Puccetti, 2007, IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation, Nat. Rev. Immunol., 7, 817, 10.1038/nri2163

Puel, 2010, Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I, J. Exp. Med., 207, 291, 10.1084/jem.20091983

Qiu, 2012, The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells, Immunity, 36, 92, 10.1016/j.immuni.2011.11.011

Rijnen, 1999, Genetic characterization of the major lactococcal aromatic aminotransferase and its involvement in conversion of amino acids to aroma compounds, Appl. Environ. Microbiol., 65, 4873, 10.1128/AEM.65.11.4873-4880.1999

Roach, 1977, Lactobacilli isolated from the stomach of conventional mice, Appl. Environ. Microbiol., 33, 1197, 10.1128/AEM.33.5.1197-1203.1977

Romani, 2011, Immunity to fungal infections, Nat. Rev. Immunol., 11, 275, 10.1038/nri2939

Satoh-Takayama, 2008, Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense, Immunity, 29, 958, 10.1016/j.immuni.2008.11.001

Savage, 1969, Microbial interference between indigenous yeast and lactobacilli in the rodent stomach, J. Bacteriol., 98, 1278, 10.1128/JB.98.3.1278-1283.1969

Scupham, 2006, Abundant and diverse fungal microbiota in the murine intestine, Appl. Environ. Microbiol., 72, 793, 10.1128/AEM.72.1.793-801.2006

Sjögren, 2009, Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses, Clin. Exp. Allergy, 39, 1842, 10.1111/j.1365-2222.2009.03326.x

Sobel, 2007, Vulvovaginal candidosis, Lancet, 369, 1961, 10.1016/S0140-6736(07)60917-9

Spits, 2013, Innate lymphoid cells—a proposal for uniform nomenclature, Nat. Rev. Immunol., 13, 145, 10.1038/nri3365

Tannock, 2004, A special fondness for lactobacilli, Appl. Environ. Microbiol., 70, 3189, 10.1128/AEM.70.6.3189-3194.2004

Tannock, 1984, The derivation and use of mice which do not harbour lactobacilli in the gastrointestinal tract, Can. J. Microbiol., 30, 849, 10.1139/m84-131

Tannock, 1974, Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract, Infect. Immun., 9, 591, 10.1128/IAI.9.3.591-598.1974

Tannock, 1982, Colonization of tissue surfaces in the gastrointestinal tract of gnotobiotic animals by lactobacillus strains, Can. J. Microbiol., 28, 1196, 10.1139/m82-177

Tannock, 2012, Resource partitioning in relation to cohabitation of Lactobacillus species in the mouse forestomach, ISME J., 6, 927, 10.1038/ismej.2011.161

Ubeda, 2010, Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans, J. Clin. Invest., 120, 4332, 10.1172/JCI43918

van Baarlen, 2011, Human mucosal in vivo transcriptome responses to three lactobacilli indicate how probiotics may modulate human cellular pathways, Proc. Natl. Acad. Sci. USA, 108, 4562, 10.1073/pnas.1000079107

Voltan, 2008, Lactobacillus crispatus M247-derived H2O2 acts as a signal transducing molecule activating peroxisome proliferator activated receptor-gamma in the intestinal mucosa, Gastroenterology, 135, 1216, 10.1053/j.gastro.2008.07.007

Walter, 2011, Host-microbial symbiosis in the vertebrate gastrointestinal tract and the Lactobacillus reuteri paradigm, Proc. Natl. Acad. Sci. USA, 108, 4645, 10.1073/pnas.1000099107

Wikoff, 2009, Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites, Proc. Natl. Acad. Sci. USA, 106, 3698, 10.1073/pnas.0812874106

Yamaguchi, 2005, Gastric colonization of Candida albicans differs in mice fed commercial and purified diets, J. Nutr., 135, 109, 10.1093/jn/135.1.109