Transporters involved in the hepatic uptake of 99mTc-mebrofenin and indocyanine green

de Graaf, 2010, Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation, J Nucl Med, 51, 742, 10.2967/jnumed.109.069435

Koneru, 1994, Clearance of indocyanine green in the evaluation of liver donors, Transplantation, 58, 729, 10.1097/00007890-199409000-00018

Lau, 1997, Evaluation of preoperative hepatic function in patients with hepatocellular carcinoma undergoing hepatectomy, Br J Surg, 84, 1255, 10.1002/bjs.1800840917

Krishnamurthy, 1989, Technetium-99m-iminodiacetic acid organic anions: review of biokinetics and clinical application in hepatology, Hepatology, 9, 139, 10.1002/hep.1840090123

Cooke, 1963, Use of indocyanine green as a test of liver function, Am J Dig Dis, 8, 244, 10.1007/BF02232323

Paumgartner, 1975, The handling of indocyanine green by the liver, Schweiz Med Wochenschr, 105, 1

de Graaf W, Heger M, Spruijt O, Maas A, de Bruin K, Hoekstra R, et al. Quantitative assessment of liver function after ischemia–reperfusion injury and partial hepatectomy in rats. J Surg Res 2010. doi:10.1016/j.jss.2010.06.038.

Hagenbuch, 2004, Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties, Pflugers Arch, 447, 653, 10.1007/s00424-003-1168-y

Konig, 2006, Pharmacogenomics of human OATP transporters, Naunyn Schmiedebergs Arch Pharmacol, 372, 432, 10.1007/s00210-006-0040-y

Sekine, 2000, The multispecific organic anion transporter (OAT) family, Pflugers Arch, 440, 337, 10.1007/s004240000297

Ho, 2006, Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics, Gastroenterology, 130, 1793, 10.1053/j.gastro.2006.02.034

Cui, 2001, Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6, J Biol Chem, 276, 9626, 10.1074/jbc.M004968200

Hata, 2003, Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake, Am J Physiol Gastrointest Liver Physiol, 285, G829, 10.1152/ajpgi.00352.2002

Lan, 1988, Uptake of technetium 99m hepatobiliary imaging agents by cultured rat hepatocytes, Gastroenterology, 95, 1625, 10.1016/S0016-5085(88)80087-8

Okuda, 1986, Studies of the hepatocellular uptake of the hepatobiliary scintiscanning agent 99mTc-DISIDA, J Hepatol, 3, 251, 10.1016/S0168-8278(86)80035-6

Ghibellini, 2008, Use of Tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies, Pharm Res, 25, 1851, 10.1007/s11095-008-9597-0

Gui, 2008, Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3, Eur J Pharmacol, 584, 57, 10.1016/j.ejphar.2008.01.042

Treiber, 2007, Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil, Drug Metab Dispos, 35, 1400, 10.1124/dmd.106.013615

de Waart, 2010, Hepatic transport mechanisms of cholyl-l-lysyl-fluorescein, J Pharmacol Exp Ther, 334, 78, 10.1124/jpet.110.166991

Leuthold, 2009, Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters, Am J Physiol Cell Physiol, 296, C570, 10.1152/ajpcell.00436.2008

Kullak-Ublick, 2001, Organic anion-transporting polypeptide B [OATP-B) and its functional comparison with three other OATPs of human liver, Gastroenterology, 120, 525, 10.1053/gast.2001.21176

Hagenbuch, 1994, Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter, J Clin Invest, 93, 1326, 10.1172/JCI117091

Jacquemin, 1994, Expression cloning of a rat liver Na(+)-independent organic anion transporter, Proc Natl Acad Sci USA, 91, 133, 10.1073/pnas.91.1.133

Hagenbuch, 2008, Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family, Xenobiotica, 38, 778, 10.1080/00498250801986951

Abels, 2000, Indocyanine green (ICG) and laser irradiation induce photooxidation, Arch Dermatol Res, 292, 404, 10.1007/s004030000147

Chang, 2005, The interaction of indocyanine green with human retinal pigment epithelium, Invest Ophthalmol Vis Sci, 46, 1463, 10.1167/iovs.04-0825

Wei, 2003, Selective uptake of indocyanine green by reticulocytes in circulation, Invest Ophthalmol Vis Sci, 44, 4489, 10.1167/iovs.03-0041

Briz, 2003, Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta–maternal liver tandem excretory pathway for foetal bilirubin, Biochem J, 371, 897, 10.1042/bj20030034

Wang, 2003, The human organic anion transport protein SLC21A6 is not sufficient for bilirubin transport, J Biol Chem, 278, 20695, 10.1074/jbc.M301100200

Geier, 2007, Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration, Biochim Biophys Acta, 1773, 283, 10.1016/j.bbamcr.2006.04.014

Krishnamurthy, 2006, Cholescintigraphic measurement of liver function: how is it different from other methods?, Eur J Nucl Med Mol Imaging, 33, 1103, 10.1007/s00259-006-0182-7

Doo, 1991, Quantification of hepatobiliary function as an integral part of imaging with technetium-99m-mebrofenin in health and disease, J Nucl Med, 32, 48

Joseph, 2005, Regulation of hepatobiliary transport activity and noninvasive identification of cytokine-dependent liver inflammation, J Nucl Med, 46, 146

Lund, 1999, Effects of LPS on transport of indocyanine green and alanine uptake in perfused rat liver, Am J Physiol, 277, G91

Geier, 2002, Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride, J Hepatol, 37, 198, 10.1016/S0168-8278(02)00108-3

Le, 2008, Down-regulation of organic anion transporter expression in human hepatocytes exposed to the proinflammatory cytokine interleukin 1beta, Drug Metab Dispos, 36, 217, 10.1124/dmd.107.016907

Siewert, 2004, Interleukin-6 regulates hepatic transporters during acute-phase response, Biochem Biophys Res Commun, 322, 232, 10.1016/j.bbrc.2004.07.102

Fisher, 2009, Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats, Eur J Pharmacol, 613, 119, 10.1016/j.ejphar.2009.04.002

Vetelainen, 2006, Hepatobiliary function assessed by(99m)Tc-mebrofenin cholescintigraphy in the evaluation of severity of steatosis in a rat model, Eur J Nucl Med Mol Imaging, 33, 1107, 10.1007/s00259-006-0125-3

de Graaf W, Bennink RJ, Heger M, Maas A, de Bruin K, van Gulik TM. Quantitative assessment of hepatic function during liver regeneration in a standardized rat model. J Nucl Med 2010;in press.

Liu, 2006, An integrated approach to model hepatic drug clearance, Eur J Pharm Sci, 29, 215, 10.1016/j.ejps.2006.05.007