Tissue regeneration potential in human umbilical cord blood

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Reed, 2008, Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types, J Cell Physiol, 215, 329, 10.1002/jcp.21312

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Fuchs, 2005, Cartilage engineering from ovine umbilical cord blood mesenchymal progenitor cells, Stem Cells, 23, 958, 10.1634/stemcells.2004-0310

Chachques, 2009, Cellular cardiac regenerative therapy in which patients?, Expert Rev Cardiovasc Ther, 7, 911, 10.1586/erc.09.84

Henning, 2004, Human umbilical cord blood mononuclear cells for the treatment of acute myocardial infarction, Cell Transplant, 13, 729, 10.3727/000000004783983477

Ma, 2005, Human cord blood cells induce angiogenesis following myocardial infarction in NOD/SCID-mice, Cardiovasc Res, 66, 45, 10.1016/j.cardiores.2004.12.013

Hirata, 2005, Human umbilical cord blood cells improve cardiac function after myocardial infarction, Biochem Biophys Res Commun, 327, 609, 10.1016/j.bbrc.2004.12.044

Botta, 2004, Heart infarct in NOD-SCID mice: therapeutic vasculogenesis by transplantation of human CD34+ cells and low dose CD34+KDR+ cells, FASEB J, 18, 1392, 10.1096/fj.03-0879fje

Leor, 2006, Human umbilical cord blood derived CD133‏ cells enhance function and repair of the infracted myocardium, Stem Cells, 24, 772, 10.1634/stemcells.2005-0212

Chen, 2005, Combined cord blood stem cells and gene therapy enhances angiogenesis and improves cardiac performance in mouse after acute myocardial infarction, Eur J Clin Invest, 35, 677, 10.1111/j.1365-2362.2005.01565.x

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Ingram, 2004, Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood, Blood, 104, 2752, 10.1182/blood-2004-04-1396

Murohara, 2000, Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization, J Clin Invest, 105, 1527, 10.1172/JCI8296

Kalka, 2000, Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization, Proc Natl Acad Sci USA, 97, 3422, 10.1073/pnas.070046397

Pesce, 2003, Myoendothelial differentiation of human umbilical cord blood-derived stem cells in ischemic limb tissues, Circ Res, 93, 51, 10.1161/01.RES.0000090624.04507.45

Das, 2009, Ex vivo nanofiber expansion and genetic modification of human cord blood-derived progenitor/stem cells enhances vasculogenesis, Cell Transplant, 18, 305, 10.3727/096368909788534870

Kim, 2006, Successful stem cell therapy using umbilical cord blood-derived multipotent stem cells for Buerger’s disease and ischemic limb disease animal model, Stem Cells, 24, 1620, 10.1634/stemcells.2005-0365

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Mcguckin, 2004, Umbilical cord blood stem cells can expand hematopoietic and neuroglial progenitors in vitro, Exp Cell Res, 295, 350, 10.1016/j.yexcr.2003.12.028

Arien-Zakay, 2009, Interferon-gamma-induced neuronal differentiation of human umbilical cord blood-derived progenitors, Leukemia, 23, 1790, 10.1038/leu.2009.106

Chen, 2005, Human umbilical cord blood progenitors: the potential of these hematopoietic cells to become neural, Stem Cells, 23, 1560, 10.1634/stemcells.2004-0284

Jang, 2004, Retinoic acid mediated induction of neurons and glial cells from human umbilical cord-derived hematopoietic stem cells, J Neurosci Res, 75, 573, 10.1002/jnr.10789

Sun, 2005, Voltage-sensitive and ligand-gated channels in differentiating neural stem-like cells derived from the nonhematopoietic fraction of human umbilical cord blood, Stem Cells, 23, 931, 10.1634/stemcells.2004-0316

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Buzanska, 2006, Neural stem-like cell line derived from a nonhematopoietic population of human umbilical cord blood, Stem Cells Develop, 15, 391, 10.1089/scd.2006.15.391

Rogers, 2007, Identification and analysis of in vitro cultured CD45-positive cells capable of multi-lineage differentiation, Exp Cell Res, 313, 1839, 10.1016/j.yexcr.2007.02.029

Chen, 2001, Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats, Stroke, 32, 2682, 10.1161/hs1101.098367

Vendrame, 2004, Infusion of human umbilical cord blood cells in a rat model of stroke dose dependently rescues behavioral deficits and reduces infarct volume, Stroke, 35, 2390, 10.1161/01.STR.0000141681.06735.9b

Newcomb, 2006, Timing of cord blood treatment after experimental stroke determines therapeutic efficacy, Cell Transplant, 15, 213, 10.3727/000000006783982043

Xiao, 2005, Transplantation of a novel cell line population of umbilical cord blood stem cells ameliorates neurological deficits associated with ischemic brain injury, Stem Cells Dev, 14, 722, 10.1089/scd.2005.14.722

Newman, 2006, Cytokines produced by cultured human umbilical cord blood (HUCB) cells: implications for brain repair, Exp Neurol, 199, 201, 10.1016/j.expneurol.2006.04.001

Arien-Zakay, 2009, Neuroprotection by cord blood neural progenitors involves antioxidants, neurotrophic and angiogenic factors, Exp Neurol, 216, 83, 10.1016/j.expneurol.2008.11.006

Chen, 2006, Infusion of human umbilical cord blood cells protect against cerebral ischemia and damage during heatstroke in the rat, Exp Neurol, 199, 67, 10.1016/j.expneurol.2005.11.015

Taguchi, 2004, Administration of CD34‏ cells after stroke enhances neurogenesis via angiogenesis in a mouse model, J Clin Invest, 114, 330, 10.1172/JCI200420622

Lu, 2002, Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury, Cell Transplant, 11, 275, 10.3727/096020198389924

Meier, 2006, Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells, Pediatr Res, 59, 244, 10.1203/01.pdr.0000197309.08852.f5

Fu, 2006, Conversion of human umbilical cord mesenchymal stem cells in Wharton’s jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism, Stem Cells, 24, 115, 10.1634/stemcells.2005-0053

Weiss, 2006, Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson’s disease, Stem Cells, 24, 781, 10.1634/stemcells.2005-0330

Garbuzova-Davis, 2003, Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation, J Hematother Stem Cell Res, 12, 255, 10.1089/152581603322022990

Garbuzova-Davis, 2008, Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose, PLoS One, 3, e2494, 10.1371/journal.pone.0002494

Nikolic, 2008, Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice, Stem Cells Develop, 17, 1, 10.1089/scd.2008.0018

Saporta, 2003, Human umbilical cord blood stem cells infusion in spinal cord injury: engraftment and beneficial influence on behavior, J Hematother Stem Cell Res, 12, 271, 10.1089/152581603322023007

Nishio, 2006, The use of hemopoietic stem cells derived from human umbilical cord blood to promote restoration of spinal cord tissue and recovery of hindlimb function in adult rats, J Neurosurg Spine, 5, 424, 10.3171/spi.2006.5.5.424

Prasad, 2008, Emerging trends in transplantation of inherited metabolic diseases, Bone Marrow Transplant, 41, 99, 10.1038/sj.bmt.1705970

Escolar, 2005, Transplantation of umbilical- cord blood in babies with infantile Krabbe’s disease, N Engl J Med, 352, 2069, 10.1056/NEJMoa042604

Staba, 2004, Cord-blood transplants from unrelated donors in patients with Hurler’s syndrome, N Engl J Med, 350, 1960, 10.1056/NEJMoa032613

Boelens, 2007, Outcomes of hematopoietic stem cell transplantation for Hurler’s syndrome in Europe: a risk factor analysis for graft failure, Bone Marrow Transplant, 40, 225, 10.1038/sj.bmt.1705718

Couri, 2008, Potential role of stem cell therapy in type 1 diabetes mellitus, Arq Bras Endocrinol Metabol, 52, 407, 10.1590/S0004-27302008000200029

Limbert, 2008, Beta-cell replacement and regeneration: strategies of cell-based therapy for type 1 diabetes mellitus, Diabetes Res Clin Pract, 79, 389, 10.1016/j.diabres.2007.06.016

Gao, 2008, In vitro cultivation of islet-like cell clusters from human umbilical cord blood-derived mesenchymal stem cells, Transl Res, 151, 293, 10.1016/j.trsl.2008.03.003

Parekh, 2009, Differentiation of human umbilical cord blood-derived mononuclear cells to endocrine pancreatic lineage, Differentiation, 78, 232, 10.1016/j.diff.2009.07.004

Ende, 2004, Transplantation of human umbilical cord blood cells improves glycemia and glomerular hypertrophy in type 2 diabetic mice, Biochem Biophys Res Commun, 321, 168, 10.1016/j.bbrc.2004.06.121

Naruse, 2005, Therapeutic neovascularization using cord blood-derived endothelial progenitor cells for diabetic neuropathy, Diabetes, 54, 1823, 10.2337/diabetes.54.6.1823

Haller, 2009, Autologous umbilical cord blood transfusion in very young children with type 1 diabetes, Diabetes Care, 32, 2041, 10.2337/dc09-0967