Human umbilical cord blood cells: a new alternative for myocardial repair?

1999 Cleland, 2001, The heart failure epidemic: exactly how big is it?, Eur Heart J, 22, 623, 10.1053/euhj.2000.2493 Hoes, 1998, An epidemic of heart failure? Recent evidence from Europe, Eur Heart J, 19, L2 Redfield, 2002, Heart failure: an epidemic of uncertain proportions, N Engl J Med, 347, 1442, 10.1056/NEJMe020115 Mann, 1999, Mechanisms and models in heart failure: a combinatorial approach, Circulation, 100, 999, 10.1161/01.CIR.100.9.999 Etzion, 2001, Myocardial regeneration: present and future trends, Am J Cardiovasc Drugs, 1, 233, 10.2165/00129784-200101040-00002 Lee, 2004, Stem-cell transplantation in myocardial infarction: a status report, Ann Intern Med, 140, 729, 10.7326/0003-4819-140-9-200405040-00013 Minatoguchi, 2004, Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment, Circulation, 109, 2572, 10.1161/01.CIR.0000129770.93985.3E Askari, 2003, Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy, Lancet, 362, 697, 10.1016/S0140-6736(03)14232-8 Beltrami, 2003, Adult cardiac stem cells are multipotent and support myocardial regeneration, Cell, 114, 763, 10.1016/S0092-8674(03)00687-1 Oh, 2003, Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction, Proc Natl Acad Sci USA, 100, 12313, 10.1073/pnas.2132126100 Matsuura, 2004, Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes, J Biol Chem, 279, 11384, 10.1074/jbc.M310822200 Messina, 2004, Isolation and expansion of adult cardiac stem cells from human and murine heart, Circ Res, 95, 911, 10.1161/01.RES.0000147315.71699.51 Kehat, 2001, Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes, J Clin Invest, 108, 407, 10.1172/JCI200112131 Scheubel, 2003, Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass grafting, J Am Coll Cardiol, 42, 2073, 10.1016/j.jacc.2003.07.025 Rauscher, 2003, Aging, progenitor cell exhaustion, and atherosclerosis, Circulation, 108, 457, 10.1161/01.CIR.0000082924.75945.48 Dimmeler, 2003, Aging of progenitor cells: limitation for regenerative capacity?, J Am Coll Cardiol, 42, 2081, 10.1016/j.jacc.2003.09.016 Leor, 2003, Cell transplantation and genetic engineering: new approaches to cardiac pathology, Expert Opin Biol Ther, 3, 1023, 10.1517/14712598.3.7.1023 Menasche, 2004, Cellular transplantation: hurdles remaining before widespread clinical use, Curr Opin Cardiol, 19, 154, 10.1097/00001573-200403000-00016 Smits, 2003, Catheter-based intramyocardial injection of autologous skeletal myoblasts as a primary treatment of ischemic heart failure. Clinical experience with six-month follow-up, J Am Coll Cardiol, 42, 2063, 10.1016/j.jacc.2003.06.017 Yoon, 2004, Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction, Circulation, 109, 3154, 10.1161/01.CIR.0000134696.08436.65 Vulliet, 2004, Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs, Lancet, 363, 783, 10.1016/S0140-6736(04)15695-X Thomson, 1998, Embryonic stem cell lines derived from human blastocysts, Science, 282, 1145, 10.1126/science.282.5391.1145 Mummery, 2003, Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells, Circulation, 107, 2733, 10.1161/01.CIR.0000068356.38592.68 Takahashi, 2003, Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes, Circulation, 107, 1912, 10.1161/01.CIR.0000064899.53876.A3 Nieda, 1997, Endothelial cell precursors are normal components of human umbilical cord blood, Br J Haematol, 98, 775, 10.1046/j.1365-2141.1997.2583074.x Lewis, 2000, Multi-lineage expansion potential of primitive hematopoietic progenitors: superiority of umbilical cord blood compared to mobilized peripheral blood, Exp Hematol, 28, 1087, 10.1016/S0301-472X(00)00515-4 Murohara, 2000, Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization, J Clin Invest, 105, 1527, 10.1172/JCI8296 Hristov, 2003, Endothelial progenitor cells: isolation and characterization, Trends Cardiovasc Med, 13, 201, 10.1016/S1050-1738(03)00077-X Jaroscak, 2003, Augmentation of umbilical cord blood (UCB) transplantation with ex vivo-expanded UCB cells: results of a phase 1 trial using the AastromReplicell System, Blood, 101, 5061, 10.1182/blood-2001-12-0290 Pesce, 2003, Myoendothelial differentiation of human umbilical cord blood-derived stem cells in ischemic limb tissues, Circ Res, 93, 51, 10.1161/01.RES.0000090624.04507.45 Shpall, 2002, Transplantation of ex vivo expanded cord blood, Biol Blood Marrow Transplant, 8, 368, 10.1053/bbmt.2002.v8.pm12171483 Kogler, 2004, A new human somatic stem cell from placental cord blood with intrinsic pluripotent differentiation potential, J Exp Med, 200, 123, 10.1084/jem.20040440 Murohara, 2001, Therapeutic vasculogenesis using human cord blood-derived endothelial progenitors, Trends Cardiovasc Med, 11, 303, 10.1016/S1050-1738(01)00128-1 Tsafrir, 2000, Alloreactivity of umbilical cord blood mononuclear cells: specific hyporesponse to noninherited maternal antigens, Hum Immunol, 61, 548, 10.1016/S0198-8859(00)00110-5 Cohen, 2003, Hematopoietic stem-cell transplantation using umbilical-cord blood, Leuk Lymphoma, 44, 1287, 10.1080/1042819031000077016 Kocher, 2001, Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function, Nat Med, 7, 430, 10.1038/86498 Hristov, 2003, Endothelial progenitor cells: mobilization, differentiation, and homing, Arterioscler Thromb Vasc Biol, 23, 1185, 10.1161/01.ATV.0000073832.49290.B5 Vendrame, 2004, Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume, Stroke, 35, 2390, 10.1161/01.STR.0000141681.06735.9b Willing, 2003, Intravenous versus intrastriatal cord blood administration in a rodent model of stroke, J Neurosci Res, 73, 296, 10.1002/jnr.10659 Borlongan, 2004, Central nervous system entry of peripherally injected umbilical cord blood cells is not required for neuroprotection in stroke, Stroke, 35, 2385, 10.1161/01.STR.0000141680.49960.d7 Taguchi, 2004, Administration of CD34+ cells after stroke enhances neurogenesis via angiogenesisin a mouse model, J Clin Invest, 114, 330, 10.1172/JCI200420622 Henning, 2004, Human umbilical cord blood mononuclear cells for the treatment of acute myocardial infarction, Cell Transplant, 13, 729, 10.3727/000000004783983477 Hirata, 2005, Human umbilical cord blood cells improve cardiac function after myocardial infarction, Biochem Biophys Res Commun, 327, 609, 10.1016/j.bbrc.2004.12.044 Yeh, 2003, Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo, Circulation, 108, 2070, 10.1161/01.CIR.0000099501.52718.70 Zhang, 2004, Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo, Circulation, 110, 3803, 10.1161/01.CIR.0000150796.18473.8E Balsam, 2004, Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium, Nature, 428, 668, 10.1038/nature02460 Agbulut, 2004, Comparison of human skeletal myoblasts and bone marrow-derived CD133+ progenitors for the repair of infarcted myocardium, J Am Coll Cardiol, 44, 458, 10.1016/j.jacc.2004.03.083 Kinnaird, 2004, Bone marrow-derived cells for enhancing collateral development: mechanisms, animal data, and initial clinical experiences, Circ Res, 95, 354, 10.1161/01.RES.0000137878.26174.66 Kinnaird, 2004, Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms, Circ Res, 94, 678, 10.1161/01.RES.0000118601.37875.AC Muller-Ehmsen, 2002, Rebuilding a damaged heart: long-term survival of transplanted neonatal rat cardiomyocytes after myocardial infarction and effect on cardiac function, Circulation, 105, 1720, 10.1161/01.CIR.0000013782.76324.92 Yao, 2003, Long-term outcome of fetal cell transplantation on postinfarction ventricular remodeling and function, J Mol Cell Cardiol, 35, 661, 10.1016/S0022-2828(03)00098-1 Migrino, 1997, Circulation, 96, 116, 10.1161/01.CIR.96.1.116 Taylor, 1998, Regenerating functional myocardium: improved performance after skeletal myoblast transplantation, Nat Med, 4, 929, 10.1038/nm0898-929 Perin, 2003, Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure, Circulation, 107, 2294, 10.1161/01.CIR.0000070596.30552.8B Orlic, 2001, Bone marrow cells regenerate infarcted myocardium, Nature, 410, 701, 10.1038/35070587 Stamm, 2003, Autologous bone-marrow stem-cell transplantation for myocardial regeneration, Lancet, 361, 45, 10.1016/S0140-6736(03)12110-1 Davani, 2003, Mesenchymal progenitor cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a rat cellular cardiomyoplasty model, Circulation, 108, 253 Matsubayashi, 2003, Improved left ventricular aneurysm repair with bioengineered vascular smooth muscle grafts, Circulation, 108, 219 Kellar, 2001, Scaffold-based three-dimensional human fibroblast culture provides a structural matrix that supports angiogenesis in infarcted heart tissue, Circulation, 104, 2063, 10.1161/hc4201.097192 Kehat, 2004, Electromechanical integration of cardiomyocytes derived from human embryonic stem cells, Nat Biotechnol, 22, 1282, 10.1038/nbt1014 Li, 1999, Survival and function of bioengineered cardiac grafts, Circulation, 100, 63, 10.1161/01.CIR.100.suppl_2.II-63 Leor, 2000, Bioengineered cardiac grafts: a new approach to repair the infarcted myocardium?, Circulation, 102, 56, 10.1161/01.CIR.102.suppl_3.III-56 Lanza, 2004, Regeneration of the infarcted heart with stem cells derived by nuclear transplantation, Circ Res, 94, 820, 10.1161/01.RES.0000120863.53562.DF