The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes

Paul I. Countryman1, John A. Heddle1
1Departments of Biology and Natural Science, York University, Downsview, Ontario M3J 1P3 Canada

Tóm tắt

Từ khóa


Tài liệu tham khảo

Bender, 1962, DNA synthesis and mitosis in cultures of human peripheral leukocytes, Exptl. Cell Res., 27, 221, 10.1016/0014-4827(62)90225-2

Bender, 1974, Mechanisms of chromosomal aberration production. III. Chemicals and ionizing radiation, Mutation Res., 23, 197, 10.1016/0027-5107(74)90140-7

Bond, 1958, Deoxyribonucleic acid synthesizing cells in peripheral blood of normal human beings, Science, 128, 202, 10.1126/science.128.3317.202

Carrano, 1973, The fate of chromosome aberrations, J. Theor. Biol., 38, 289, 10.1016/0022-5193(73)90176-8

Countryman, P.I. and J.A. Heddle, A true microculture technique for culturing human lymphocytes, Humangenetik, in press.

Dewey, 1971, Chromosomal aberrations and mortality of X-irradiated mammalian cells: emphais on repair, 68, 667

Dubinin, 1969, Chromosome breakage and complete genic mutation production in molecular terms, Mutation Res., 8, 353, 10.1016/0027-5107(69)90014-1

Evans, 1965, A simple microculture technique for obtaining human chromosome preparations with some comments on DNA replication in sex chromosomes of the goat, cow and pig, Exptl. Cell Res., 38, 511, 10.1016/0014-4827(65)90375-7

Evans, 1975, Human lymphocytes for the analysis of chromosome aberrations in mutagen tests, Mutation Res., 31, 135, 10.1016/0165-1161(75)90082-5

Heddle, 1973, A rapid in vivo test for chromosomal damage, Mutation Res., 18, 187, 10.1016/0027-5107(73)90035-3

Heddle, 1970, On the formation of chromosomal aberrations, Mutation Res., 9, 117, 10.1016/0027-5107(70)90075-8

Heddle, 1969, Nature of chromatid deletions, 637

Heddle, 1967, Sampling time and the complexity of the human leukocyte culture system, 6

Heddle, 1969, Changes in chromosome structure induced by radiations: a test of the two chief hypotheses, Nature, 221, 1158, 10.1038/2211158a0

Ma, 1965, Far-red induced mitotic delay and the apparent increase of X-ray induced chromatid aberrations in Tradescantia microspores, Radiation Botany, 5, 293, 10.1016/S0033-7560(65)80017-5

Matter, 1971, Trenim on-induced chromosomal damage in bone marrow of six mammalian species, evaluated by the micronucleus test, Mutation Res., 12, 417, 10.1016/0027-5107(71)90092-3

Obe, 1975, The human leukocyte test system. III. Premature chromosome condensation from chemically and X-ray induced micronuclei, Mutation Res., 27, 89, 10.1016/0027-5107(75)90276-6

Prempree, 1969, Actinomycin D: inhibition of chromosomal repair in human lymphocytes, Mutation Res., 7, 126, 10.1016/0027-5107(69)90058-X

Prempree, 1969, Radiosensitivity and repair time: the repair time of chromosome breaks produced during the different stages of the cell cycle, Mutation Res., 7, 441, 10.1016/0027-5107(69)90115-8

Revell, 1954, A new hypothesis for “chromatid” changes, 243

Sasaki, 1966, Proliferation of human lymphocytes in culture, Nature, 210, 913, 10.1038/210913a0

Sasaki, 1969, Chromosomal radiosensitivity in Down's syndrome, Jap. J. Hum. Genet., 14, 81

Sasaki, 1970, Chromosomal constitution and its bearing on the chromosomal radiosensitivity in man, Mutation Res., 10, 617, 10.1016/0027-5107(70)90089-8

Sax, 1938, Chromosome aberrations induced by X-rays, Genetics, 23, 494, 10.1093/genetics/23.5.494

Scott, 1970, Radiation-induced chromosome damage in human peripheral blood lymphocytes in vitro. II. RBE and dose rate studies with 60Co-γ and X-rays, Mutation Res., 9, 225, 10.1016/0027-5107(70)90061-8

Stefanescu, 1972, Lack of recovery from radiation induced chromosome damage in G0 human lymphocytes, Exptl. Cell Res., 71, 156, 10.1016/0014-4827(72)90273-X

Wolff, 1972, The repair of X-ray induced chromosome aberrations in stimulated and unstimulated human lymphocytes, Mutation Res., 15, 435, 10.1016/0027-5107(72)90007-3

Wolff, 1954, Independent X-ray effects on chromosome breakage and reunion, 40, 187

Wolff, 1975, The induction of chromatid deletions in accord with the breakage-and-reunion hypothesis, Mutation Res., 29, 85, 10.1016/0027-5107(75)90023-8