The emerging role of off-the-shelf engineered natural killer cells in targeted cancer immunotherapy
Tài liệu tham khảo
Abel, 2018, Natural killer cells: Development, maturation, and clinical utilization, Front. Immunol., 9, 1869, 10.3389/fimmu.2018.01869
Lanier, 2008, Up on the tightrope: Natural killer cell activation and inhibition, Nat. Immunol., 9, 495, 10.1038/ni1581
Long, 2013, Controlling natural killer cell responses: Integration of signals for activation and inhibition, Annu. Rev. Immunol., 31, 227, 10.1146/annurev-immunol-020711-075005
Quatrini, 2021, Human NK cells, their receptors and function, Eur. J. Immunol., 51, 1566, 10.1002/eji.202049028
Lo Nigro, 2019, NK-mediated antibody-dependent cell-mediated cytotoxicity in solid tumors: Biological evidence and clinical perspectives, Ann. Transl. Med., 7, 105, 10.21037/atm.2019.01.42
Coca, 1997, The prognostic significance of intratumoral natural killer cells in patients with colorectal carcinoma, Cancer, 79, 2320, 10.1002/(SICI)1097-0142(19970615)79:12<2320::AID-CNCR5>3.0.CO;2-P
Ishigami, 2000, Prognostic value of intratumoral natural killer cells in gastric carcinoma, Cancer, 88, 577, 10.1002/(SICI)1097-0142(20000201)88:3<577::AID-CNCR13>3.0.CO;2-V
Takanami, 2001, The prognostic value of natural killer cell infiltration in resected pulmonary adenocarcinoma, J. Thorac. Cardiovasc. Surg., 121, 1058, 10.1067/mtc.2001.113026
Villegas, 2002, Prognostic significance of tumor infiltrating natural killer cells subset CD57 in patients with squamous cell lung cancer, Lung Cancer, 35, 23, 10.1016/S0169-5002(01)00292-6
Remark, 2013, Characteristics and clinical impacts of the immune environments in colorectal and renal cell carcinoma lung metastases: Influence of tumor origin, Clin. Cancer Res., 19, 4079, 10.1158/1078-0432.CCR-12-3847
Imai, 2000, Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population, Lancet, 356, 1795, 10.1016/S0140-6736(00)03231-1
Tartter, 1987, The prognostic significance of natural killer cytotoxicity in patients with colorectal cancer, Arch. Surg., 122, 1264, 10.1001/archsurg.1987.01400230050009
Rosenberg, 1987, A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone, N. Engl. J. Med., 316, 889, 10.1056/NEJM198704093161501
Liu, 2021, NK cell-based cancer immunotherapy: From basic biology to clinical development, J. Hematol. Oncol., 14, 7, 10.1186/s13045-020-01014-w
Wendel, 2021, Arming immune cells for battle: A brief journey through the advancements of T and NK cell immunotherapy, Cancers (Basel), 13, 1481, 10.3390/cancers13061481
Daher, 2021, CAR-NK cells: The next wave of cellular therapy for cancer, Clin. Transl. Immunology, 10, e1274, 10.1002/cti2.1274
Franks, 2020, Natural born killers: NK cells in cancer therapy, Cancers (Basel), 12, E2131, 10.3390/cancers12082131
Klingemann, 2016, Natural killer cells for immunotherapy—Advantages of the NK-92 cell line over blood NK cells, Front. Immunol., 7, 91, 10.3389/fimmu.2016.00091
Maki, 2001, Factors regulating the cytotoxic activity of the human natural killer cell line, NK-92, J. Hematother. Stem Cell Res., 10, 369, 10.1089/152581601750288975
Romanski, 2005, Mechanisms of resistance to natural killer cell-mediated cytotoxicity in acute lymphoblastic leukemia, Exp. Hematol., 33, 344, 10.1016/j.exphem.2004.11.006
Faure, 2002, KIR2DL4 (CD158d), an NK cell-activating receptor with inhibitory potential, J. Immunol., 168, 6208, 10.4049/jimmunol.168.12.6208
Tam, 2003, Ex vivo expansion of the highly cytotoxic human natural killer-92 cell-line under current good manufacturing practice conditions for clinical adoptive cellular immunotherapy, Cytotherapy, 5, 259, 10.1080/14653240310001523
Törnroos, 2019, Culturing the human natural killer cell line NK-92 in interleukin-2 and interleukin-15—Implications for clinical trials, Anticancer Res., 39, 107, 10.21873/anticanres.13085
Swift, 2012, Natural killer cell lines preferentially kill clonogenic multiple myeloma cells and decrease myeloma engraftment in a bioluminescent xenograft mouse model, Haematologica, 97, 1020, 10.3324/haematol.2011.054254
Tam, 1999, Immunotherapy of malignant melanoma in a SCID mouse model using the highly cytotoxic natural killer cell line NK-92, J. Hematother., 8, 281, 10.1089/106161299320316
Tonn, 2013, Treatment of patients with advanced cancer with the natural killer cell line NK-92, Cytotherapy, 15, 1563, 10.1016/j.jcyt.2013.06.017
Williams, 2017, A phase I trial of NK-92 cells for refractory hematological malignancies relapsing after autologous hematopoietic cell transplantation shows safety and evidence of efficacy, Oncotarget, 8, 89256, 10.18632/oncotarget.19204
Boissel, 2016, An “off the shelf,” GMP-grade, IL-2-independent NK cell line expressing the high-affinity Fc-receptor to augment antibody therapeutics, Cancer Res., 76, 2302, 10.1158/1538-7445.AM2016-2302
Jochems, 2016, An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele, Oncotarget, 7, 86359, 10.18632/oncotarget.13411
Weng, 2003, Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma, J. Clin. Oncol., 21, 3940, 10.1200/JCO.2003.05.013
Musolino, 2008, Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer, J. Clin. Oncol., 26, 1789, 10.1200/JCO.2007.14.8957
Zhang, 2007, FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab, J. Clin. Oncol., 25, 3712, 10.1200/JCO.2006.08.8021
Bibeau, 2009, Impact of FcγRIIa-FcγRIIIa polymorphisms and KRAS mutations on the clinical outcome of patients with metastatic colorectal cancer treated with cetuximab plus irinotecan, J. Clin. Oncol., 27, 1122, 10.1200/JCO.2008.18.0463
Magnes, 2018, The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab, Pharmacogenomics J., 18, 474, 10.1038/tpj.2017.37
Lehrnbecher, 1999, Variant genotypes of the low-affinity Fcγ receptors in two control populations and a review of low-affinity Fcγ receptor polymorphisms in control and disease populations, Blood, 94, 4220, 10.1182/blood.V94.12.4220.424k08_4220_4232
Gómez Román, 2014, Antibody-dependent cellular cytotoxicity (ADCC), 1
Kistler, 2020, Safety and efficacy from first-in-human immunotherapy combining NK and T cell activation with off-the-shelf high-affinity CD16 NK cell line (haNK) in patients with 2nd-line or greater metastatic triple-negative breast cancer (TNBC), Cancer Res., 80, P5-04-02, 10.1158/1538-7445.SABCS19-P5-04-02
D’Aloia, 2018, CAR-T cells: The long and winding road to solid tumors, Cell Death Dis., 9, 282, 10.1038/s41419-018-0278-6
Gust, 2017, Endothelial activation and blood-brain barrier disruption in neurotoxicity after adoptive immunotherapy with CD19 CAR-T cells, Cancer Discov., 7, 1404, 10.1158/2159-8290.CD-17-0698
Brudno, 2016, Toxicities of chimeric antigen receptor T cells: Recognition and management, Blood, 127, 3321, 10.1182/blood-2016-04-703751
Klingemann, 2014, Are natural killer cells superior CAR drivers?, OncoImmunology, 3, e28147, 10.4161/onci.28147
Miller, 2005, Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer, Blood, 105, 3051, 10.1182/blood-2004-07-2974
Shaffer, 2016, Phase II study of haploidentical natural killer cell infusion for treatment of relapsed or persistent myeloid malignancies following allogeneic hematopoietic cell transplantation, Biol. Blood Marrow Transplant., 22, 705, 10.1016/j.bbmt.2015.12.028
Hu, 2018, Chimeric antigen receptor (CAR)-transduced natural killer cells in tumor immunotherapy, Acta Pharmacol. Sin., 39, 167, 10.1038/aps.2017.125
Lee, 2015, T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: A phase 1 dose-escalation trial, Lancet, 385, 517, 10.1016/S0140-6736(14)61403-3
Teachey, 2016, Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia, Cancer Discov., 6, 664, 10.1158/2159-8290.CD-16-0040
Zhang, 2017, Chimeric antigen receptor-engineered NK-92 cells: An off-the-shelf cellular therapeutic for targeted elimination of cancer cells and induction of protective antitumor immunity, Front. Immunol., 8, 533, 10.3389/fimmu.2017.00533
Kalos, 2011, T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia, Sci. Transl. Med., 3, 95ra73, 10.1126/scitranslmed.3002842
Fabian, 2020, PD-L1 targeting high-affinity NK (t-haNK) cells induce direct antitumor effects and target suppressive MDSC populations, J. Immunother. Cancer, 8, e000450, 10.1136/jitc-2019-000450
Dotti, 2014, Design and development of therapies using chimeric antigen receptor-expressing T cells, Immunol. Rev., 257, 107, 10.1111/imr.12131
Guedan, 2018, Engineering and design of chimeric antigen receptors, Mol. Ther. Methods Clin. Dev., 12, 145, 10.1016/j.omtm.2018.12.009
Töpfer, 2015, DAP12-based activating chimeric antigen receptor for NK cell tumor immunotherapy, J. Immunol., 194, 3201, 10.4049/jimmunol.1400330
Müller, 2015, Engineering NK cells modified with an EGFRvIII-specific chimeric antigen receptor to overexpress CXCR4 improves immunotherapy of CXCL12/SDF-1α-secreting glioblastoma, J. Immunother., 38, 197, 10.1097/CJI.0000000000000082
Schönfeld, 2015, Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor, Mol. Ther., 23, 330, 10.1038/mt.2014.219
Boissel, 2012, Comparison of mRNA and lentiviral based transfection of natural killer cells with chimeric antigen receptors recognizing lymphoid antigens, Leuk. Lymphoma, 53, 958, 10.3109/10428194.2011.634048
Boissel, 2009, Transfection with mRNA for CD19 specific chimeric antigen receptor restores NK cell mediated killing of CLL cells, Leuk. Res., 33, 1255, 10.1016/j.leukres.2008.11.024
Uherek, 2002, Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction, Blood, 100, 1265, 10.1182/blood.V100.4.1265.h81602001265_1265_1273
Liu, 2017, Driving better and safer HER2-specific CARs for cancer therapy, Oncotarget, 8, 62730, 10.18632/oncotarget.17528
Daldrup-Link, 2005, In vivo tracking of genetically engineered, anti-HER2/neu directed natural killer cells to HER2/neu positive mammary tumors with magnetic resonance imaging, Eur. Radiol., 15, 4, 10.1007/s00330-004-2526-7
Alkins, 2013, Focused ultrasound delivers targeted immune cells to metastatic brain tumors, Cancer Res., 73, 1892, 10.1158/0008-5472.CAN-12-2609
Boissel, 2013, Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity, OncoImmunology, 2, e26527, 10.4161/onci.26527
Oelsner, 2017, Continuously expanding CAR NK-92 cells display selective cytotoxicity against B-cell leukemia and lymphoma, Cytotherapy, 19, 235, 10.1016/j.jcyt.2016.10.009
Jiang, 2014, Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells, Mol. Oncol., 8, 297, 10.1016/j.molonc.2013.12.001
Chu, 2014, CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma, Leukemia, 28, 917, 10.1038/leu.2013.279
Chen, 2016, Novel anti-CD3 chimeric antigen receptor targeting of aggressive T cell malignancies, Oncotarget, 7, 56219, 10.18632/oncotarget.11019
Chen, 2017, Preclinical targeting of aggressive T-cell malignancies using anti-CD5 chimeric antigen receptor, Leukemia, 31, 2151, 10.1038/leu.2017.8
Han, 2015, CAR-engineered NK cells targeting wild-type EGFR and EGFRvIII enhance killing of glioblastoma and patient-derived glioblastoma stem cells, Sci. Rep., 5, 11483, 10.1038/srep11483
Genßler, 2015, Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival, OncoImmunology, 5, e1119354, 10.1080/2162402X.2015.1119354
Yu, 2018, Development of GPC3-specific chimeric antigen receptor-engineered natural killer cells for the treatment of hepatocellular carcinoma, Mol. Ther., 26, 366, 10.1016/j.ymthe.2017.12.012
Montagner, 2020, Anti-PSMA CAR-engineered NK-92 cells: An off-the-shelf cell therapy for prostate cancer, Cells, 9, E1382, 10.3390/cells9061382
Zhang, 2013, Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody, Immunol. Cell Biol., 91, 615, 10.1038/icb.2013.45
Zhao, 2015, Affinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential, Leukemia, 29, 2238, 10.1038/leu.2015.125
Pardoll, 2012, The blockade of immune checkpoints in cancer immunotherapy, Nat. Rev. Cancer, 12, 252, 10.1038/nrc3239
Yang, 2020, Targeting B7-H3 immune checkpoint with chimeric antigen receptor-engineered natural killer cells exhibits potent cytotoxicity against non-small cell lung cancer, Front. Pharmacol., 11, 1089, 10.3389/fphar.2020.01089
Robbins, 2020, Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells, eLife, 9, e54854, 10.7554/eLife.54854
Tambaro, 2021, Autologous CD33-CAR-T cells for treatment of relapsed/refractory acute myelogenous leukemia, Leukemia, 10.1038/s41375-021-01232-2
Burger, 2019, CAR-engineered NK cells for the treatment of glioblastoma: Turning innate effectors into precision tools for cancer immunotherapy, Front. Immunol., 10, 2683, 10.3389/fimmu.2019.02683
Li, 2019, Phase I clinical trial with PD-1/MUC1 CAR-pNK92 immunotherapy, Cancer Immunol. Res., 7, A014, 10.1158/2326-6074.CRICIMTEATIAACR18-A014
Adams, 2021, Sacituzumab govitecan and trastuzumab deruxtecan: Two new antibody-drug conjugates in the breast cancer treatment landscape, ESMO Open, 6, 100204, 10.1016/j.esmoop.2021.100204
Hermanson, 2015, Utilizing chimeric antigen receptors to direct natural killer cell activity, Front. Immunol., 6, 195, 10.3389/fimmu.2015.00195