The distribution of cholesterol and phospholipid composition in submitochondrial membranes from bovine adrenal cortex: Fundamental studies of steroidogenic mitochondria

Lipids - Tập 18 Số 9 - Trang 577-584 - 1983
Behling Cheng1, Tokuji Kimura1
1Department of Chemistry, Wayne State University, Detroit, MI 48202;

Tóm tắt

AbstractThe cholesterol contents and phospholipid compositions of mitochondria, microsomes and submitochondrial membranes from bovine adrenal cortex have been analyzed quantitatively. From our results, the following cholesterol contents were obtained: mitochondria, 6.2±0.9 mol %; microsomes, 18.4±2.8 mol %; mitochondrial inner membrane, 2.8±0.6 mol %; and mitochondrial outer membrane, 8.3±1.3 mol %. In addition, the phospholipid compositions of the mitochondrial inner and outer membranes were determined for the first time. Cardiolipin was found to be enriched in the inner membrane, whereas phosphatidylinositol was richer in the outer membrane. The general features of phospholipid compositions in the submitochondrial membranes resembled that of rat liver mitochondria.

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Tài liệu tham khảo

10.1007/BF02354909

10.1016/S0021-9258(17)34636-7

10.1016/S0021-9258(19)86728-5

10.1111/j.1432-1033.1972.tb01931.x

10.1016/0303-7207(79)90082-0

10.1016/S0021-9258(19)70690-5

10.1073/pnas.77.12.7189

10.1016/0076-6879(79)55012-5

10.1016/0003-2697(79)90737-1

10.1093/clinchem/25.6.976

10.1515/bchm2.1974.355.1.279

10.1016/B978-0-12-395630-9.50142-0

Zak B., 1977, Ann. Clin. Lab. Sci., 7, 169

10.1016/0006-291X(65)90198-1

Farnararo M., 1980, Comp. Biochem. Physiol., 66, 427

10.1016/0076-6879(67)10061-X

10.1016/S0021-9258(18)69497-9

10.1016/0003-9861(62)90458-7

10.1016/0003-2697(73)90376-X

10.1016/S0021-9258(20)82244-3

10.1016/S0021-9258(18)57021-6

10.1016/0014-4827(80)90070-1

10.1002/ar.1092030403

10.1507/endocrj1954.28.245

10.1083/jcb.37.2.482

10.1016/S0021-9258(18)50414-2

10.1016/0005-2736(71)90123-4

10.1016/0022-4731(75)90167-3

10.1016/S0006-291X(74)80361-X

Fonseca E., 1980, Comp. Biochem. Physiol., 66, 543

10.1007/BF02533864

10.1515/bchm2.1974.355.2.797

10.1007/BF02533066

10.1016/0005-2736(73)90270-8

10.1007/BF02534312

10.1093/oxfordjournals.jbchem.a129414

10.1016/S0021-9258(18)50596-2

10.1016/0003-9861(81)90153-3

10.1111/j.1432-1033.1977.tb11243.x

10.1016/S0021-9258(19)43115-3

10.1016/S0021-9258(19)70620-6

10.1016/S0022-2275(20)40133-6

Blaschko H., 1966, Biochem. J., 98, 24P

10.1083/jcb.91.3.227s

DeKruijff B., 1976, Biochim. Biophys. Acta, 436, 7129

10.1016/0005-2736(75)90300-4

10.1016/0005-2736(89)90004-7

10.1016/S0021-9258(19)70012-X

10.1016/S0021-9258(19)69200-8