The clinical and microbiological efficacy of temocillin versus cefotaxime in adults with febrile urinary tract infection, and its effects on the intestinal microbiota: a randomised multicentre clinical trial in Sweden

The Lancet Infectious Diseases - Tập 22 - Trang 390-400 - 2022
Charlotta Edlund1, Anders Ternhag1,2, Gunilla Skoog Ståhlgren1, Petra Edquist1, Åse Östholm Balkhed3, Simon Athlin4, Emeli Månsson5, Maria Tempé6, Jakob Bergström1, Christian G Giske7,8, Håkan Hanberger3
1The Public Health Agency of Sweden, Solna, Sweden
2Division of Infectious Diseases, Department of Medicine, Karolinska Institutet, Solna, Sweden
3Division of Infectious Diseases, Department of Biomedical and Clinical Sciences, Faculty of Medicine, Linköping University, Linköping, Sweden
4Department of Infectious Diseases, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
5Department of Infectious Diseases and Centre of Clinical Research, Västmanland Hospital, Västerås, Sweden
6Sundsvall Härnösand Regional Hospital, Sundsvall, Sweden
7Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, Solna, Sweden
8Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden

Tài liệu tham khảo

Pieri, 2020, Country income is only one of the tiles: the global journey of antimicrobial resistance among humans, animals, and environment, Antibiotics (Basel), 9, 9 Sullivan, 2001, Effect of antimicrobial agents on the ecological balance of human microflora, Lancet Infect Dis, 1, 101, 10.1016/S1473-3099(01)00066-4 Cassini, 2019, Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis, Lancet Infect Dis, 19, 56, 10.1016/S1473-3099(18)30605-4 Fröding, 2019, Prediction of bloodstream infection caused by extended-spectrum β-lactamase-producing Enterobacterales in patients with suspected community-onset sepsis, Int J Antimicrob Agents, 53, 820, 10.1016/j.ijantimicag.2019.02.008 Paterson, 2004, “Collateral damage” from cephalosporin or quinolone antibiotic therapy, Clin Infect Dis, 38, S341, 10.1086/382690 Settle, 1998, Prospective study of the risk of Clostridium difficile diarrhoea in elderly patients following treatment with cefotaxime or piperacillin-tazobactam, Aliment Pharmacol Ther, 12, 1217, 10.1046/j.1365-2036.1998.00428.x Dong, 2020, Emerging superbugs: the threat of carbapenem resistant Enterobacteriaceae, AIMS Microbiol, 6, 176, 10.3934/microbiol.2020012 Woerther, 2018, Carbapenems and alternative β-lactams for the treatment of infections due to extended-spectrum β-lactamase-producing Enterobacteriaceae: what impact on intestinal colonisation resistance?, Int J Antimicrob Agents, 52, 762, 10.1016/j.ijantimicag.2018.08.026 Theuretzbacher, 2015, Reviving old antibiotics, J Antimicrob Chemother, 70, 2177, 10.1093/jac/dkv157 Kresken, 2021, Temocillin susceptibility in Enterobacterales with an ESBL/AmpC phenotype, Int J Antimicrob Agents, 57, 10.1016/j.ijantimicag.2020.106223 Giske, 2015, Contemporary resistance trends and mechanisms for the old antibiotics colistin, temocillin, fosfomycin, mecillinam and nitrofurantoin, Clin Microbiol Infect, 21, 899, 10.1016/j.cmi.2015.05.022 Kuch, 2020, Activity of temocillin against ESBL-, AmpC-, and/or KPC-producing Enterobacterales isolated in Poland, Eur J Clin Microbiol Infect Dis, 39, 1185, 10.1007/s10096-020-03844-5 Alexandre, 2018, Pharmacokinetics and pharmacodynamics of temocillin, Clin Pharmacokinet, 57, 287, 10.1007/s40262-017-0584-7 Mittermayer, 1985, Influence of temocillin on human bowel flora, Drugs, 29, 43, 10.2165/00003495-198500295-00010 Boon, 1985, Studies with temocillin in the hamster model of antibiotic-associated colitis, Drugs, 29, 57, 10.2165/00003495-198500295-00012 Chenouard, 2021, Impact of ceftriaxone and temocillin on fecal abundance of extended-spectrum β-lactamase producing Escherichia coli in a mouse model, PLoS One, 16, 10.1371/journal.pone.0248177 Balakrishnan, 2011, Temocillin use in England: clinical and microbiological efficacies in infections caused by extended-spectrum and/or derepressed AmpC β-lactamase-producing Enterobacteriaceae, J Antimicrob Chemother, 66, 2628, 10.1093/jac/dkr317 Laterre, 2015, Temocillin (6 g daily) in critically ill patients: continuous infusion versus three times daily administration, J Antimicrob Chemother, 70, 891, 10.1093/jac/dku465 Elvers, 2020, Antibiotic-induced changes in the human gut microbiota for the most commonly prescribed antibiotics in primary care in the UK: a systematic review, BMJ Open, 10, 10.1136/bmjopen-2019-035677 Kahan, 2014, Accounting for centre-effects in multicentre trials with a binary outcome - when, why, and how?, BMC Med Res Methodol, 14, 20, 10.1186/1471-2288-14-20 De Vries-Hospers, 1985, Influence of temocillin on colonisation resistance and consequences for therapy, Drugs, 29, 227, 10.2165/00003495-198500295-00050 Burdet, 2019, Ceftriaxone and cefotaxime have similar effects on the intestinal microbiota in human volunteers treated by standard-dose regimens, Antimicrob Agents Chemother, 63, e02244, 10.1128/AAC.02244-18 Habayeb, 2015, Amoxicillin plus temocillin as an alternative empiric therapy for the treatment of severe hospital-acquired pneumonia: results from a retrospective audit, Eur J Clin Microbiol Infect Dis, 34, 1693, 10.1007/s10096-015-2406-x Isendahl, 2019, Temporal dynamics and risk factors for bloodstream infection with extended-spectrum β-lactamase-producing bacteria in previously-colonized individuals: national population-based cohort study, Clin Infect Dis, 68, 641, 10.1093/cid/ciy539 Cornejo-Juárez, 2016, Fecal ESBL Escherichia coli carriage as a risk factor for bacteremia in patients with hematological malignancies, Support Care Cancer, 24, 253, 10.1007/s00520-015-2772-z Engler-Hüsch, 2018, In-hospital costs of community-acquired colonization with multidrug-resistant organisms at a German teaching hospital, BMC Health Serv Res, 18, 737, 10.1186/s12913-018-3549-0