The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP

Nature - Tập 492 Số 7427 - Trang 123-127 - 2012
Geun‐Shik Lee1, Naeha Subramanian2, Andrew I. Kim1, Ivona Aksentijevich1, Raphaela Goldbach‐Mansky3, David B. Sacks4, Ronald N. Germain2, Daniel L. Kastner1, Jae Jin Chae1
1Inflammatory Disease Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, 20892, Maryland, USA
2Laboratory of Systems Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, 20892, Maryland, USA
3Translational Autoinflammatory Disease Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, 20892, Maryland, USA
4Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, 20892, Maryland, USA

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