The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
Tóm tắt
Từ khóa
Tài liệu tham khảo
Browning, 2004, Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity, HEPATOLOGY, 40, 1387, 10.1002/hep.20466
Adams, 2005, The natural history of nonalcoholic fatty liver disease: a population-based cohort study, Gastroenterology, 129, 113, 10.1053/j.gastro.2005.04.014
Neuschwander-Tetri, 2003, Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference, HEPATOLOGY, 37, 1202, 10.1053/jhep.2003.50193
Sanyal, 2005, Mechanisms of disease: pathogenesis of nonalcoholic fatty liver disease, Nat Clin Pract Gastroenterol Hepatol, 2, 46, 10.1038/ncpgasthep0084
Browning, 2004, Ethnic differences in the prevalence of cryptogenic cirrhosis, Am J Gastroenterol, 99, 292, 10.1111/j.1572-0241.2004.04059.x
Struben, 2000, Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds, Am J Med, 108, 9, 10.1016/S0002-9343(99)00315-0
Willner, 2001, Ninety patients with nonalcoholic steatohepatitis: insulin resistance, familial tendency, and severity of disease, Am J Gastroenterol, 96, 2957, 10.1111/j.1572-0241.2001.04667.x
Hindorff LA Junkins HA Mehta JP Manolio TA www.genome.gov/gwastudies 2010
Romeo, 2008, Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease, Nat Genet, 40, 1461, 10.1038/ng.257
Yuan, 2008, Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes, Am J Hum Genet, 83, 520, 10.1016/j.ajhg.2008.09.012
Kantartzis, 2009, Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene, Diabetes, 58, 2616, 10.2337/db09-0279
Kotronen, 2009, A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans, Diabetologia, 52, 1056, 10.1007/s00125-009-1285-z
Kollerits, 2010, A common variant in the adiponutrin gene influences liver enzyme levels, J Med Genet, 47, 116, 10.1136/jmg.2009.066597
Romeo, 2010, Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent, Int J Obes (Lond), 34, 190, 10.1038/ijo.2009.216
Chalasani, 2009, Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic steatohepatitis: PIVENS trial design, Contemp Clin Trials, 30, 88, 10.1016/j.cct.2008.09.003
Lavine, 2010, Treatment of nonalcoholic fatty liver disease in children: TONIC trial design, Contemp Clin Trials, 31, 62, 10.1016/j.cct.2009.09.001
Promrat, 2004, A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis, HEPATOLOGY, 39, 188, 10.1002/hep.20012
Loomba, 2009, Clinical trial: pilot study of metformin for the treatment of nonalcoholic steatohepatitis, Aliment Pharmacol Ther, 29, 172, 10.1111/j.1365-2036.2008.03869.x
Brunt, 2009, Portal chronic inflammation in nonalcoholic fatty liver disease (NAFLD): a histologic marker of advanced NAFLD-Clinicopathologic correlations from the nonalcoholic steatohepatitis clinical research network, HEPATOLOGY, 49, 809, 10.1002/hep.22724
Kleiner, 2005, Design and validation of a histological scoring system for nonalcoholic fatty liver disease, HEPATOLOGY, 41, 1313, 10.1002/hep.20701
Glynn, 1995, Determinants of bone mineral density in older men, J Bone Miner Res, 10, 1769, 10.1002/jbmr.5650101121
WHO Multicentre Growth Reference Study Group, 2006, The WHO Child Growth Standards: Length/Height-for-Age, Weight-for-Age, Weight-for-Length, Weight-for-Height, and Body Mass Index-for-Age: Methods and Development
Minelli, 2005, The choice of a genetic model in the meta-analysis of molecular association studies, Int J Epidemiol, 34, 1319, 10.1093/ije/dyi169
Benjamini, 1995, Controlling the false discovery rate: a practical and powerful approach to multiple testing, J R Stat Soc Series B Stat Methodol, 57, 289
He, 2010, A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis, J Biol Chem, 285, 6706, 10.1074/jbc.M109.064501
Yeh, 2007, Pathology of nonalcoholic fatty liver disease, Am J Clin Pathol, 128, 837, 10.1309/RTPM1PY6YGBL2G2R
Schwimmer, 2005, Histopathology of pediatric nonalcoholic fatty liver disease, HEPATOLOGY, 42, 641, 10.1002/hep.20842
Sookoian, 2009, A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity, J Lipid Res, 50, 2111, 10.1194/jlr.P900013-JLR200
Loomba, 2009, Advances in pediatric nonalcoholic fatty liver disease, HEPATOLOGY, 50, 1282, 10.1002/hep.23119
Mohanty, 2009, Influence of ethnicity on histological differences in non-alcoholic fatty liver disease, J Hepatol, 50, 797, 10.1016/j.jhep.2008.11.017
Baulande, 2001, Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineage, J Biol Chem, 276, 33336, 10.1074/jbc.M105193200
Liu, 2004, Adiponutrin: A new gene regulated by energy balance in human adipose tissue, J Clin Endocrinol Metab, 89, 2684, 10.1210/jc.2003-031978
Polson, 2004, Macronutrient composition of the diet differentially affects leptin and adiponutrin mRNA expression in response to meal feeding, J Nutr Biochem, 15, 242, 10.1016/j.jnutbio.2003.11.009
Faraj, 2006, Insulin regulation of gene expression and concentrations of white adipose tissue-derived proteins in vivo in healthy men: relation to adiponutrin, J Endocrinol, 191, 427, 10.1677/joe.1.06659
Moldes, 2006, Adiponutrin gene is regulated by insulin and glucose in human adipose tissue, Eur J Endocrinol, 155, 461, 10.1530/eje.1.02229
Kershaw, 2006, Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin, Diabetes, 55, 148, 10.2337/diabetes.55.01.06.db05-0982
Jenkins, 2004, Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities, J Biol Chem, 279, 48968, 10.1074/jbc.M407841200
Johansson, 2009, Genetic variance in the adiponutrin gene family and childhood obesity, PLoS One, 4, e5327, 10.1371/journal.pone.0005327
Johansson, 2008, Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity, Eur J Endocrinol, 159, 577, 10.1530/EJE-08-0426
