The Role of Fungi in Diseases of the Nose and Sinuses

American Journal of Rhinology and Allergy - Tập 26 Số 5 - Trang 351-358 - 2012
Zachary M. Soler1, Rodney J. Schlosser1
1Division of Rhinology and Sinus Surgery, Department of Otolaryngology–Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina

Tóm tắt

Background Human exposure to fungal elements is inevitable, with normal respiration routinely depositing fungal hyphae within the nose and paranasal sinuses. Fungal species can cause sinonasal disease, with clinical outcomes ranging from mild symptoms to intracranial invasion and death. There has been much debate regarding the precise role fungal species play in sinonasal disease and optimal treatment strategies. Methods A literature review of fungal diseases of the nose and sinuses was conducted. Results Presentation, diagnosis, and current management strategies of each recognized form of fungal rhinosinusitis was reviewed. Conclusion Each form of fungal rhinosinusitis has a characteristic presentation and clinical course, with the immune status of the host playing a critical pathophysiological role. Accurate diagnosis and targeted treatment strategies are necessary to achieve optimal outcomes.

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Thông tin xuất bản

American Journal of Rhinology and Allergy

Tập 26 Số 5

351-358

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