The Membrane-Anchored MMP Inhibitor RECK Is a Key Regulator of Extracellular Matrix Integrity and Angiogenesis

Cell - Tập 107 Số 6 - Trang 789-800 - 2001
Junseo Oh1, Rei Takahashi2, Soichiro Kondo1, Akira Mizoguchi3, Eijiro Adachi4, Regina Maki Sasahara1, Shigehiro Nishimura1,5, Yukio Imamura1, Hitoshi Kitayama1, David B. Alexander1, Chizuka Idé3, Thomas P. Horan6, Tsutomu Arakawa6, Hisahito Yoshida7, Shin‐Ichi Nishikawa7, Yoshifumi Itoh8, Motoharu Seiki8, Shigeyoshi Itohara5, Chiaki Takahashi1, Makoto Noda1
1Department of Molecular Oncology, Kyoto 606-8501, Japan
2Department of Pathology and Tumor Biology, Kyoto 606-8501, Japan
3Department of Anatomy and Neurobiology, Kyoto 606-8501, Japan
4Department of Molecular Morphology, Kitasato University Graduate School of Medical Sciences, Sagamihara, Kanagawa 228-8555, Japan
5RIKEN Brain Research Institute, Wako-Shi, Saitama 351-0198, Japan
6Amgen Inc., Amgen Center, Thousand Oaks, CA 91320 USA
7Department of Molecular Genetics, Kyoto University Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan
8Department of Cancer Research, Institute of Medical Science, University of Tokyo, Tokyo 108-0071, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Birkedal-Hansen, 1995, Proteolytic remodeling of extracellular matrix, Curr. Opin. Cell Biol., 7, 728, 10.1016/0955-0674(95)80116-2

Brew, 2000, Tissue inhibitors of metalloproteinases, evolution, structure and function, Biochim. Biophys. Acta, 1477, 267, 10.1016/S0167-4838(99)00279-4

Brown, 1984, Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080, EMBO J., 3, 1321, 10.1002/j.1460-2075.1984.tb01970.x

Canete-Soler, 1995, Developmental expression of MMP-9 (Gelatinase B) mRNA in mouse embryos, Dev. Dyn., 204, 30, 10.1002/aja.1002040105

Caterina, 2000, Inactivating mutation of the mouse tissue inhibitor of metalloproteinase-2 (Timp-2) gene alters proMMP-2 activation, J. Biol. Chem., 275, 26416, 10.1074/jbc.M001271200

Coussens, 2000, MMP-9 supplied by bone marrow-derived cells contribute to skin carcinogenesis, Cell, 103, 481, 10.1016/S0092-8674(00)00139-2

Davies, 1993, Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion, Cancer Res., 53, 5365

Ellerbroek, 1999, Membrane associated matrix metalloproteinases in metastasis, Bioessays, 21, 940, 10.1002/(SICI)1521-1878(199911)21:11<940::AID-BIES6>3.0.CO;2-J

Fagan, 1981, Effects of transformation on fibronectin gene expression using cloned fibronectin cDNA, J. Biol. Chem., 256, 520, 10.1016/S0021-9258(19)70169-0

Folkman, 1996, Blood vessel formation, Cell, 87, 1153, 10.1016/S0092-8674(00)81810-3

Furumoto, 2001, RECK gene expression in hepatocellular carcinoma, Correlation with invasion-related clinicopathological factors and its clinical significance, Hepatology, 33, 189, 10.1053/jhep.2001.21048

Garbisa, 1987, Secretion of type IV collagenolytic protease and metastatic phenotype, induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2–E1a, Cancer Res., 47, 1523

Gomi, 1995, Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions, Neuron, 14, 29, 10.1016/0896-6273(95)90238-4

Hanahan, 1997, Signaling vascular morphogenesis and maintenance, Science, 277, 48, 10.1126/science.277.5322.48

Hanahan, 1996, Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis, Cell, 86, 353, 10.1016/S0092-8674(00)80108-7

Hidalgo, 2001, Development of matrix metalloproteinase inhibitors in cancer therapy, J. Natl. Cancer Inst., 93, 178, 10.1093/jnci/93.3.178

Howard, 1978, Decreased levels of collagen mRNA in rous sarcoma virus-transformed chick embryo fibroblasts, J. Biol. Chem., 253, 5869, 10.1016/S0021-9258(17)30349-6

Ikeda, 2000, Inhibition of gelatinolytic activity in tumor tissues by synthetic matrix metalloproteinase inhibitor, Clin. Cancer Res., 6, 3290

Itoh, 1997, Unaltered secretion of β-amyloid precursor protein in gelatinase A (Matrix Metalloproteinase 2)-deficient mice, J. Biol. Chem., 272, 22389, 10.1074/jbc.272.36.22389

Kahari, 1999, Matrix metalloproteinases and their inhibition in tumour growth and invasion, Ann. Med., 31, 34, 10.3109/07853899909019260

Kitayama, 1989, A ras-related gene with transformation suppressor activity, Cell, 56, 77, 10.1016/0092-8674(89)90985-9

Kinoshita, 1997, Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures, Genes Dev., 11, 1535, 10.1101/gad.11.12.1535

Kinoshita, 1998, TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads, J. Biol. Chem., 273, 16098, 10.1074/jbc.273.26.16098

Knight, 1992, A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases, FEBS Lett., 296, 263, 10.1016/0014-5793(92)80300-6

Lohler, 1984, Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesechymal cell death, Cell, 38, 597, 10.1016/0092-8674(84)90514-2

Matsuo, 1999, Preservation of pathological tissue specimens by freeze-drying for immunohisochemical staining and various molecular biological analyses, Pathol. Int., 49, 383, 10.1046/j.1440-1827.1999.00887.x

Nagase, 1999, Matrix metalloproteinases, J. Biol. Chem., 274, 21491, 10.1074/jbc.274.31.21491

Niwa, 1991, Efficient selection for high-expression transfectants with a novel eukaryotic vector, Gene, 108, 193, 10.1016/0378-1119(91)90434-D

Noda, 1989, Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes, Proc. Natl. Acad. Sci. USA, 86, 162, 10.1073/pnas.86.1.162

Nothnick, 1997, Assessment of the role of tissue inhibitor of metalloproteinase-1 (TIMP-1) during the periovulatory period in female mice lacking a functional TIMP-1 gene, Biol. Reprod., 56, 1181, 10.1095/biolreprod56.5.1181

Ohuchi, 1997, Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules, J. Biol. Chem., 272, 2446, 10.1074/jbc.272.4.2446

Pei, 1996, Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity, J. Biol. Chem., 271, 9135, 10.1074/jbc.271.15.9135

Plantefaber, 1989, Changes in integrin receptors on oncogenically transformed cells, Cell, 56, 281, 10.1016/0092-8674(89)90902-1

Reponen, 1992, Molecular cloning of murine 72-kDa type IV collagenase and its expression duirng mouse development, J. Biol. Chem., 267, 7856, 10.1016/S0021-9258(18)42592-6

Risau, 1997, Mechanisms of angiogenesis, Nature, 386, 671, 10.1038/386671a0

Sasahara, 1999, Involvement of the Sp1 site in ras-mediated downregulation of the RECK metastasis suppressor gene, Biochem. Biophys. Res. Commun., 264, 668, 10.1006/bbrc.1999.1552

Sato, 1994, A matrix metalloproteinase expressed on the surface of invasive tumor cells, Nature, 370, 61, 10.1038/370061a0

Schlaeger, 1995, Vascular endothelial cell lineage-specific promoter in transgenic mice, Development, 121, 1089, 10.1242/dev.121.4.1089

Stetler-Stevenson, 1999, Matrix metalloproteinasese in angiogenesis, J. Clin. Inv., 103, 1237, 10.1172/JCI6870

Takahashi, 1996, Characterization of a human MSX-2 cDNA and its fragment isolated as a transformation suppressor gene against v-Ki-ras oncogene, Oncogene, 12, 2137

Takahashi, 1998, Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK, Proc. Natl. Acad. Sci. USA, 95, 13221, 10.1073/pnas.95.22.13221

Thant, 1997, c-Ras is required for the activation of the matrix metalloproteinases by concanavalin A in 3Y1 cells, FEBS Lett., 406, 28, 10.1016/S0014-5793(97)00230-5

Vu, 2000, Matrix metalloproteinases, effectors of development and normal physiology, Genes Dev., 14, 2123, 10.1101/gad.815400

Wang, 2000, TIMP-2 is required for efficient activation of proMMP-2 in vivo, J. Biol. Chem., 275, 26411, 10.1074/jbc.M001270200

Werb, 1997, ECM and cell surface proteolysis, regulating cellular ecology, Cell, 91, 439, 10.1016/S0092-8674(00)80429-8

Yagi, 1990, Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection, Proc. Natl. Acad. Sci. USA, 87, 9918, 10.1073/pnas.87.24.9918

Yamamoto, 1996, Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro, Cancer Res., 56, 384

Yancopoulos, 2000, Vascular-specific growth factors and blood vessel formation, Nature, 407, 242, 10.1038/35025215