The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

Cell - Tập 63 Số 4 - Trang 843-849 - 1990
George A. Martin1, David Viskoohil2, Gideon Bollag1, Peter C. McCabe1, Walter J. Crosier1, Heinz Haubruck1, L Conroy1, R.J. Clark1, P. OʼConnell3, Richard Cawthon3, Michael A. Innis1, Frank McCormick1
1Department of Molecular Biology Cetus Corporation Emeryville, California 94608 USA
2Department of Pediatrics and Howard Hughes Medical Institute University of Utah School of Medicine Salt Lake City, Utah 84132 USA
3Department of Human Genetics and Howard Hughes Medical Institute University of Utah School of Medicine Salt Lake City, Utah 84132 USA

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Adari, 1988, Guanosine triphosphate activating protein (GAP) interacts wiith the p21 ras effector binding domain, Science, 240, 518, 10.1126/science.2833817

Ballester, 1989, Genetic analysis of mammalian GAP expressed in yeast, Cell, 59, 681, 10.1016/0092-8674(89)90014-7

Bar-Sagi, 1985, Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation, Cell, 42, 841, 10.1016/0092-8674(85)90280-6

Borasio, 1989, ras p21 protein promotes survival and fiber outgrowth of cultured embryonic neurons, Neuron, 2, 1087, 10.1016/0896-6273(89)90233-X

Bos, 1989, Ras oncogenes in human cancer: a review, Cancer Res., 49, 4682

Broek, 1985, Differential activation of yeast adenylate cyclase by wild-type and mutant RAS proteins, Cell, 41, 763, 10.1016/S0092-8674(85)80057-X

Buchberg, 1990, Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway, Nature, 347, 291, 10.1038/347291a0

Cawthon, 1990, A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations, Cell, 62, 193, 10.1016/0092-8674(90)90253-B

Ellis, 1990, Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases, Nature, 343, 377, 10.1038/343377a0

Frech, 1990, Inhibition of GTPase activating protein stimulation of ras p21 GTPase by the Krev-1 gene product, Science, 249, 169, 10.1126/science.2164710

Furth, 1982, Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family, J. Virol., 43, 294, 10.1128/JVI.43.1.294-304.1982

Halenbeck, 1990, Purification, characterization, and western blot analysis of human GTPase activating protein (GAP) from native and recombinant sources, J. Biol. Chem., 10.1016/S0021-9258(18)45826-7

Hall, 1990, ras and GAP—who's controlling whom?, Cell, 61, 921, 10.1016/0092-8674(90)90054-I

Innis, 1990

Kaplan, 1990, PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex, Cell, 61, 125, 10.1016/0092-8674(90)90220-9

Kazlauskas, 1990, Binding of GAP to activated PDGF receptors, Science, 247, 1578, 10.1126/science.2157284

Kitayama, 1989, A ras-related gene with transformation suppressor activity, Cell, 56, 77, 10.1016/0092-8674(89)90985-9

Klebe, 1983, A general method for polyethylene-glycol-induced genetic transformation of bacteria and yeast, Gene, 25, 333, 10.1016/0378-1119(83)90238-X

Luckow, 1988, Trends in the development of baculovirus expression vectors, Biotechnology, 6, 47, 10.1038/nbt0188-47

MacArthur, 1984, Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen, J. Virol., 52, 483, 10.1128/JVI.52.2.483-491.1984

Maiorella, 1988, Large-scale insect cell culture for recombinant protein production, Biotechnology, 6, 1406, 10.1038/nbt1288-1406

Marshall, 1987, Regulatory function of the Saccharomyces cerevisiae RAS C-terminus, Mol. Cell. Biol., 7, 2309, 10.1128/MCB.7.7.2309

Marshall, 1989, A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity, EMBO J., 8, 1105, 10.1002/j.1460-2075.1989.tb03480.x

Molloy, 1989, PDGF induction of tyrosine phosphorylation of GTPase activating protein, Nature, 342, 711, 10.1038/342711a0

Ridley, 1988, ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation, EMBO J., 7, 1635, 10.1002/j.1460-2075.1988.tb02990.x

Satoh, 1987, Induction of neurite formation in PC12 cells by microinjection of proto-oncogenic Ha-ras protein pre-incubated with guanosine-5′-O-(3-thiotriphosphate), Mol. Cell. Biol., 7, 4553, 10.1128/MCB.7.12.4553

Schneider, 1982, A one-step purification of membrane proteins using a high efficiency immunomatrix, J. Biol. Chem., 257, 10766, 10.1016/S0021-9258(18)33889-4

Sheela, 1990, Angiogenic and invasive properties of neurofibroma Schwann cells, J. Cell. Biol., 111, 645, 10.1083/jcb.111.2.645

Sherman, 1986

Smith, 1983, Production of human β-interferon in insect cells infected with a baculovirus expression vector, Mol. Cell. Biol., 3, 2156, 10.1128/MCB.3.12.2156

Smith, 1984, Requirement for c-ras proteins during viral oncogene transformation, Nature, 320, 540, 10.1038/320540a0

Summers, 1987, A manual of methods for baculovirus vectors and insect cell culture procedures, Texas Agricultural Experiment Station Bulletin, 1555

Tanaka, 1989, IRA1, an inhibitory regulator of the RAS/cyclic AMP pathway in Saccharomyces cerevisiae, Mol. Cell. Biol., 9, 757, 10.1128/MCB.9.2.757

Tanaka, 1990, S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein, Cell, 60, 803, 10.1016/0092-8674(90)90094-U

Tanaka, 1990, IRA2, a second gene of Saccharomyces cerevislae that encodes a protein with a domain homologous to mammalian ras GTPase activating protein, Mol. Cell. Biol., 10, 4303, 10.1128/MCB.10.8.4303

Toda, 1985, In yeast, RAS proteins are controlling elements of adenylate cyclase, Cell, 40, 27, 10.1016/0092-8674(85)90305-8

Trahey, 1987, A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants, Science, 238, 542, 10.1126/science.2821624

Trahey, 1988, Molecular cloning of two types of GAP complementary DNA from human placenta, Science, 242, 1697, 10.1126/science.3201259

Viskochil, 1990, Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus, Cell, 62, 187, 10.1016/0092-8674(90)90252-A

Vogel, 1988, Cloning of bovine GAP and its interaction with oncogenic ras p21, Nature, 335, 90, 10.1038/335090a0

Wallace, 1990, Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients, Science, 249, 181, 10.1126/science.2134734

Xu, 1990, The neurofibromatosis type 1 gene encodes a protein related to GAP, Cell, 62, 599, 10.1016/0092-8674(90)90024-9