The Diverse Functions of MicroRNAs in Animal Development and Disease

Developmental Cell - Tập 11 Số 4 - Trang 441-450 - 2006
Wigard P. Kloosterman1, Ronald H.A. Plasterk1,2
1Hubrecht Laboratory, Centre for Biomedical Genetics, Uppsalalaan 8, 3584, CT, Utrecht, the Netherlands
2University of Utrecht, 3508 TC Utrecht, The Netherlands

Tóm tắt

Từ khóa


Tài liệu tham khảo

Abbott, 2005, The let-7 microRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans, Dev. Cell, 9, 403, 10.1016/j.devcel.2005.07.009

Abelson, 2005, Sequence variants in SLITRK1 are associated with Tourette's syndrome, Science, 310, 317, 10.1126/science.1116502

Aboobaker, 2005, Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development, Proc. Natl. Acad. Sci. USA, 102, 18017, 10.1073/pnas.0508823102

Abrahante, 2003, The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs, Dev. Cell, 4, 625, 10.1016/S1534-5807(03)00127-8

Andl, 2006, The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles, Curr. Biol., 16, 1041, 10.1016/j.cub.2006.04.005

Ason, 2006, Differences in vertebrate miRNA expression, Proc. Natl. Acad. Sci. USA, 103, 14385, 10.1073/pnas.0603529103

Bagga, 2005, Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation, Cell, 122, 553, 10.1016/j.cell.2005.07.031

Bartel, 2004, Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs, Nat. Rev. Genet., 5, 396, 10.1038/nrg1328

Berezikov, 2006, Approaches to microRNA discovery, Nat. Genet., 38, S2, 10.1038/ng1794

Bernstein, 2003, Dicer is essential for mouse development, Nat. Genet., 35, 215, 10.1038/ng1253

Boehm, 2005, A developmental timing microRNA and its target regulate life span in C. elegans, Science, 310, 1954, 10.1126/science.1115596

Brennecke, 2003, bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila, Cell, 113, 25, 10.1016/S0092-8674(03)00231-9

Bruno, 2006, P-bodies react to stress and nonsense, Cell, 125, 1036, 10.1016/j.cell.2006.06.003

Cai, 2004, Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs, RNA, 10, 1957, 10.1261/rna.7135204

Cai, 2005, Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells, Proc. Natl. Acad. Sci. USA, 102, 5570, 10.1073/pnas.0408192102

Calin, 2002, Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia, Proc. Natl. Acad. Sci. USA, 99, 15524, 10.1073/pnas.242606799

Calin, 2004, MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias, Proc. Natl. Acad. Sci. USA, 101, 11755, 10.1073/pnas.0404432101

Calin, 2005, A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia, N. Engl. J. Med., 353, 1793, 10.1056/NEJMoa050995

Chang, 2004, MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode, Nature, 430, 785, 10.1038/nature02752

Chen, 2004, MicroRNAs modulate hematopoietic lineage differentiation, Science, 303, 83, 10.1126/science.1091903

Chen, 2006, The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation, Nat. Genet., 38, 228, 10.1038/ng1725

Ciafre, 2005, Extensive modulation of a set of microRNAs in primary glioblastoma, Biochem. Biophys. Res. Commun., 334, 1351, 10.1016/j.bbrc.2005.07.030

Cimmino, 2005, miR-15 and miR-16 induce apoptosis by targeting BCL2, Proc. Natl. Acad. Sci. USA, 102, 13944, 10.1073/pnas.0506654102

Clop, 2006, A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep, Nat. Genet., 38, 813, 10.1038/ng1810

Conaco, 2006, Reciprocal actions of REST and a microRNA promote neuronal identity, Proc. Natl. Acad. Sci. USA, 103, 2422, 10.1073/pnas.0511041103

Cullen, 2006, Viruses and microRNAs, Nat. Genet., 38, S25, 10.1038/ng1793

Dews, 2006, Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster, Nat. Genet., 38, 1060, 10.1038/ng1855

Doench, 2004, Specificity of microRNA target selection in translational repression, Genes Dev., 18, 504, 10.1101/gad.1184404

Fang, 2005, Promoter and 3′-untranslated-region haplotypes in the vitamin d receptor gene predispose to osteoporotic fracture: the rotterdam study, Am. J. Hum. Genet., 77, 807, 10.1086/497438

Farh, 2005, The widespread impact of mammalian microRNAs on mRNA repression and evolution, Science, 310, 1817, 10.1126/science.1121158

Fazi, 2005, A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPα regulates human granulopoiesis, Cell, 123, 819, 10.1016/j.cell.2005.09.023

Giraldez, 2005, MicroRNAs regulate brain morphogenesis in zebrafish, Science, 308, 833, 10.1126/science.1109020

Giraldez, 2006, Zebrafish miR-430 promotes deadenylation and clearance of maternal mRNAs, Science, 312, 75, 10.1126/science.1122689

Gottwein, 2006, A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing, J. Virol., 80, 5321, 10.1128/JVI.02734-05

Grey, 2005, Identification and characterization of human cytomegalovirus-encoded microRNAs, J. Virol., 79, 12095, 10.1128/JVI.79.18.12095-12099.2005

Grosshans, 2005, The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans, Dev. Cell, 8, 321, 10.1016/j.devcel.2004.12.019

Grundhoff, 2006, A combined computational and microarray-based approach identifies novel microRNAs encoded by human γ-herpesviruses, RNA, 12, 733, 10.1261/rna.2326106

Hammond, 2005, Dicing and slicing: the core machinery of the RNA interference pathway, FEBS Lett., 579, 5822, 10.1016/j.febslet.2005.08.079

Harfe, 2005, The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb, Proc. Natl. Acad. Sci. USA, 102, 10898, 10.1073/pnas.0504834102

Harris, 2006, Dicer function is essential for lung epithelium morphogenesis, Proc. Natl. Acad. Sci. USA, 103, 2208, 10.1073/pnas.0510839103

Hatfield, 2005, Stem cell division is regulated by the microRNA pathway, Nature, 435, 974, 10.1038/nature03816

He, 2005, A microRNA polycistron as a potential human oncogene, Nature, 435, 828, 10.1038/nature03552

Hornstein, 2005, The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development, Nature, 438, 671, 10.1038/nature04138

Hutvagner, 2005, Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation, FEBS Lett., 579, 5850, 10.1016/j.febslet.2005.08.071

Iwai, 2005, Polymorphisms in human pre-miRNAs, Biochem. Biophys. Res. Commun., 331, 1439, 10.1016/j.bbrc.2005.04.051

Johnson, 2005, RAS is regulated by the let-7 microRNA family, Cell, 120, 635, 10.1016/j.cell.2005.01.014

Johnston, 2003, A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans, Nature, 426, 845, 10.1038/nature02255

Jopling, 2005, Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA, Science, 309, 1577, 10.1126/science.1113329

Kanellopoulou, 2005, Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing, Genes Dev., 19, 489, 10.1101/gad.1248505

Karube, 2005, Reduced expression of Dicer associated with poor prognosis in lung cancer patients, Cancer Sci., 96, 111, 10.1111/j.1349-7006.2005.00015.x

Ketting, 2001, Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans, Genes Dev., 15, 2654, 10.1101/gad.927801

Kim, 2004, MicroRNA precursors in motion: exportin-5 mediates their nuclear export, Trends Cell Biol., 14, 156, 10.1016/j.tcb.2004.02.006

Kim, 2005, MicroRNA biogenesis: coordinated cropping and dicing, Nat. Rev. Mol. Cell Biol., 6, 376, 10.1038/nrm1644

Kim, 2006, Small RNAs just got bigger: Piwi-interacting RNAs (piRNAs) in mammalian testes, Genes Dev., 20, 1993, 10.1101/gad.1456106

Kloosterman, 2006, In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes, Nat. Methods, 3, 27, 10.1038/nmeth843

Lagos-Quintana, 2001, Identification of novel genes coding for small expressed RNAs, Science, 294, 853, 10.1126/science.1064921

Lai, 2005, Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs, Genes Dev., 19, 1067, 10.1101/gad.1291905

Lau, 2001, An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans, Science, 294, 858, 10.1126/science.1065062

Leaman, 2005, Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development, Cell, 121, 1097, 10.1016/j.cell.2005.04.016

Lecellier, 2005, A cellular microRNA mediates antiviral defense in human cells, Science, 308, 557, 10.1126/science.1108784

Lee, 2001, An extensive class of small RNAs in Caenorhabditis elegans, Science, 294, 862, 10.1126/science.1065329

Lee, 1993, The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14, Cell, 75, 843, 10.1016/0092-8674(93)90529-Y

Lee, 2003, The nuclear RNase III Drosha initiates microRNA processing, Nature, 425, 415, 10.1038/nature01957

Lee, 2004, MicroRNA genes are transcribed by RNA polymerase II, EMBO J., 23, 4051, 10.1038/sj.emboj.7600385

Lewis, 2005, Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets, Cell, 120, 15, 10.1016/j.cell.2004.12.035

Li, 2005, Regulatory mutations of mir-48, a C. elegans let-7 family microRNA, cause developmental timing defects, Dev. Cell, 9, 415, 10.1016/j.devcel.2005.08.002

Li, 2005, A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye, Cell, 123, 1267, 10.1016/j.cell.2005.10.040

Lim, 2005, Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs, Nature, 433, 769, 10.1038/nature03315

Lin, 2003, The C. elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target, Dev. Cell, 4, 639, 10.1016/S1534-5807(03)00124-2

Lu, 2005, MicroRNA expression profiles classify human cancers, Nature, 435, 834, 10.1038/nature03702

Meister, 2004, Mechanisms of gene silencing by double-stranded RNA, Nature, 431, 343, 10.1038/nature02873

Michael, 2003, Reduced accumulation of specific microRNAs in colorectal neoplasia, Mol. Cancer Res., 1, 882

Moss, 2003, Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites, Dev. Biol., 258, 432, 10.1016/S0012-1606(03)00126-X

Murchison, 2005, Characterization of Dicer-deficient murine embryonic stem cells, Proc. Natl. Acad. Sci. USA, 102, 12135, 10.1073/pnas.0505479102

Naguibneva, 2006, The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation, Nat. Cell Biol., 8, 278, 10.1038/ncb1373

O'Donnell, 2005, c-Myc-regulated microRNAs modulate E2F1 expression, Nature, 435, 839, 10.1038/nature03677

Ota, 2004, Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma, Cancer Res., 64, 3087, 10.1158/0008-5472.CAN-03-3773

Pasquinelli, 2000, Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA, Nature, 408, 86, 10.1038/35040556

Petersen, 2006, Short RNAs repress translation after initiation in mammalian cells, Mol. Cell, 21, 533, 10.1016/j.molcel.2006.01.031

Pfeffer, 2004, Identification of virus-encoded microRNAs, Science, 304, 734, 10.1126/science.1096781

Pfeffer, 2005, Identification of microRNAs of the herpesvirus family, Nat. Methods, 2, 269, 10.1038/nmeth746

Pillai, 2005, Inhibition of translational initiation by let-7 microRNA in human cells, Science, 309, 1573, 10.1126/science.1115079

Plasterk, 2006, Micro RNAs in animal development, Cell, 124, 877, 10.1016/j.cell.2006.02.030

Poy, 2004, A pancreatic islet-specific microRNA regulates insulin secretion, Nature, 432, 226, 10.1038/nature03076

Reinhart, 2000, The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans, Nature, 403, 901, 10.1038/35002607

Saito, 2006, Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome, Genes Dev., 20, 2214, 10.1101/gad.1454806

Samols, 2005, Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi's sarcoma-associated herpesvirus, J. Virol., 79, 9301, 10.1128/JVI.79.14.9301-9305.2005

Schratt, 2006, A brain-specific microRNA regulates dendritic spine development, Nature, 439, 283, 10.1038/nature04367

Sokol, 2005, Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth, Genes Dev., 19, 2343, 10.1101/gad.1356105

Sood, 2006, Cell-type-specific signatures of microRNAs on target mRNA expression, Proc. Natl. Acad. Sci. USA, 103, 2746, 10.1073/pnas.0511045103

Stark, 2005, Animal microRNAs confer robustness to gene expression and have a significant impact on 3′UTR evolution, Cell, 123, 1133, 10.1016/j.cell.2005.11.023

Sullivan, 2005, SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells, Nature, 435, 682, 10.1038/nature03576

Takamizawa, 2004, Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival, Cancer Res., 64, 3753, 10.1158/0008-5472.CAN-04-0637

Teleman, 2006, Drosophila lacking microRNA miR-278 are defective in energy homeostasis, Genes Dev., 20, 417, 10.1101/gad.374406

Thomson, 2006, Extensive post-transcriptional regulation of microRNAs and its implications for cancer, Genes Dev., 20, 2202, 10.1101/gad.1444406

Tuddenham, 2006, The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells, FEBS Lett., 580, 4214, 10.1016/j.febslet.2006.06.080

Vagin, 2006, A distinct small RNA pathway silences selfish genetic elements in the germline, Science, 313, 320, 10.1126/science.1129333

Valencia-Sanchez, 2006, Control of translation and mRNA degradation by miRNAs and siRNAs, Genes Dev., 20, 515, 10.1101/gad.1399806

Vo, 2005, A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis, Proc. Natl. Acad. Sci. USA, 102, 16426, 10.1073/pnas.0508448102

Volinia, 2006, A microRNA expression signature of human solid tumors defines cancer gene targets, Proc. Natl. Acad. Sci. USA, 103, 2257, 10.1073/pnas.0510565103

Voorhoeve, 2006, A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors, Cell, 124, 1169, 10.1016/j.cell.2006.02.037

Wienholds, 2003, The microRNA-producing enzyme Dicer1 is essential for zebrafish development, Nat. Genet., 35, 217, 10.1038/ng1251

Wienholds, 2005, MicroRNA expression in zebrafish embryonic development, Science, 309, 310, 10.1126/science.1114519

Wightman, 1993, Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans, Cell, 75, 855, 10.1016/0092-8674(93)90530-4

Xie, 2005, Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals, Nature, 434, 338, 10.1038/nature03441

Xu, 2003, The Drosophila microRNA mir-14 suppresses cell death and is required for normal fat metabolism, Curr. Biol., 13, 790, 10.1016/S0960-9822(03)00250-1

Yanaihara, 2006, Unique microRNA molecular profiles in lung cancer diagnosis and prognosis, Cancer Cell, 9, 189, 10.1016/j.ccr.2006.01.025

Yi, 2006, Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs, Nat. Genet., 38, 356, 10.1038/ng1744

Yoo, 2005, LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans, Science, 310, 1330, 10.1126/science.1119481

Zeng, 2003, Sequence requirements for micro RNA processing and function in human cells, RNA, 9, 112, 10.1261/rna.2780503

Zhang, 2006, microRNAs exhibit high frequency genomic alterations in human cancer, Proc. Natl. Acad. Sci. USA, 103, 9136, 10.1073/pnas.0508889103

Zhao, 2005, Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis, Nature, 436, 214, 10.1038/nature03817