The Burden of Cardiovascular Disease in the Elderly: Morbidity, Mortality, and Costs

Clinics in Geriatric Medicine - Tập 25 Số 4 - Trang 563-577 - 2009
Ali Yazdanyar1, Anne B. Newman2
1Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Room 518, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA
2Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Room 532, 130 North Bellefield Avenue, Pittsburgh, PA 15213, USA

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Tài liệu tham khảo

U.S. Census Bureau, 2008

Fried, 1991, The Cardiovascular Health Study: design and rationale, Ann Epidemiol, 1, 263, 10.1016/1047-2797(91)90005-W

Lloyd-Jones, 2009, Heart disease and stroke statistics–2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee, Circulation, 119, e21, 10.1161/CIRCULATIONAHA.108.191261

National Institute of Health, 2006

Arnold, 2005, Incidence of cardiovascular disease in older Americans: the cardiovascular health study, J Am Geriatr Soc, 53, 211, 10.1111/j.1532-5415.2005.53105.x

Lloyd-Jones, 1999, Lifetime risk of developing coronary heart disease, Lancet, 353, 89, 10.1016/S0140-6736(98)10279-9

National Heart, Lung, and Blood Institute, 2007

Mittelmark, 1993, Prevalence of cardiovascular diseases among older adults. The Cardiovascular Health Study, Am J Epidemiol, 137, 311, 10.1093/oxfordjournals.aje.a116678

Rich, 1992, Is age an independent predictor of early and late mortality in patients with acute myocardial infarction?, Am J Med, 92, 7, 10.1016/0002-9343(92)90008-Y

National Center for Health Statistics

Lloyd-Jones, 2002, Lifetime risk for developing congestive heart failure: the Framingham Heart Study, Circulation, 106, 3068, 10.1161/01.CIR.0000039105.49749.6F

Breek, 2001, Quality of life in patients with intermittent claudication using the World Health Organisation (WHO) questionnaire, Eur J Vasc Endovasc Surg, 21, 118, 10.1053/ejvs.2001.1305

Izquierdo-Porrera, 2005, Relationship between objective measures of peripheral arterial disease severity to self-reported quality of life in older adults with intermittent claudication, J Vasc Surg, 41, 625, 10.1016/j.jvs.2005.01.012

Newman, 1993, Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group, Circulation, 88, 837, 10.1161/01.CIR.88.3.837

Barasch, 2006, Clinical significance of calcification of the fibrous skeleton of the heart and aortosclerosis in community dwelling elderly. The Cardiovascular Health Study (CHS), Am Heart J, 151, 39, 10.1016/j.ahj.2005.03.052

Roberts, 1986, The senile cardiac calcification syndrome, Am J Cardiol, 58, 572, 10.1016/0002-9149(86)90045-7

Roberts, 1998, Comparison of cardiac findings at necropsy in octogenarians, nonagenarians, and centenarians, Am J Cardiol, 82, 627, 10.1016/S0002-9149(98)00385-3

Fox, 2003, Mitral annular calcification predicts cardiovascular morbidity and mortality, Circulation, 107, 1492, 10.1161/01.CIR.0000058168.26163.BC

Benjamin, 1992, Mitral annular calcification and the risk of stroke in an elderly cohort, N Engl J Med, 327, 374, 10.1056/NEJM199208063270602

Savage, 1983, Prevalence of submitral (anular) calcium and its correlates in a general population-based sample (the Framingham Study), Am J Cardiol, 51, 1375, 10.1016/0002-9149(83)90315-6

Lindroos, 1993, Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample, J Am Coll Cardiol, 21, 1220, 10.1016/0735-1097(93)90249-Z

Otto, 1999, Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly, N Engl J Med, 341, 142, 10.1056/NEJM199907153410302

Stewart, 1997, Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study, J Am Coll Cardiol, 29, 630, 10.1016/S0735-1097(96)00563-3

Singh, 1999, Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study), Am J Cardiol, 83, 897, 10.1016/S0002-9149(98)01064-9

Nkomo, 2006, Burden of valvular heart diseases: a population-based study, Lancet, 368, 1005, 10.1016/S0140-6736(06)69208-8

Freed, 1999, Prevalence and clinical outcome of mitral-valve prolapse, N Engl J Med, 341, 1, 10.1056/NEJM199907013410101

Furberg, 1992, Major electrocardiographic abnormalities in persons aged 65 years and older (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group, Am J Cardiol, 69, 1329, 10.1016/0002-9149(92)91231-R

Manolio, 1994, Cardiac arrhythmias on 24-h ambulatory electrocardiography in older women and men: the Cardiovascular Health Study, J Am Coll Cardiol, 23, 916, 10.1016/0735-1097(94)90638-6

Miyasaka, 2006, Secular trends in incidence of atrial fibrillation in Olmstead County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence, Circulation, 114, 119, 10.1161/CIRCULATIONAHA.105.595140

Furberg, 1994, Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study), Am J Cardiol, 74, 236, 10.1016/0002-9149(94)90363-8

Lloyd-Jones, 2004, Lifetime risk for development of atrial fibrillation, Circulation, 110, 1042, 10.1161/01.CIR.0000140263.20897.42

Psaty, 1997, Incidence of and risk factors for atrial fibrillation in older adults, Circulation, 96, 2455, 10.1161/01.CIR.96.7.2455

Kuller, 1994, Prevalence of subclinical atherosclerosis and cardiovascular disease and association with risk factors in the Cardiovascular Health Study, Am J Epidemiol, 139, 1164, 10.1093/oxfordjournals.aje.a116963

Newman, 2001, Coronary artery calcification in older adults to age 99: prevalence and risk factors, Circulation, 104, 2679, 10.1161/hc4601.099464

Yue, 1997, Sulcal, ventricular, and white matter changes at MR imaging in the aging brain: data from the cardiovascular health study, Radiology, 202, 33, 10.1148/radiology.202.1.8988189

Bryan, 1997, Infarct-like lesions in the brain: prevalence and anatomic characteristics at MR imaging of the elderly–data from the Cardiovascular Health Study, Radiology, 202, 47, 10.1148/radiology.202.1.8988191

Newman, 2001, Associations of subclinical cardiovascular disease with frailty, J Gerontol A Biol Sci Med Sci, 56, M158, 10.1093/gerona/56.3.M158

Newman, 2003, “Successful aging”: effect of subclinical cardiovascular disease, Arch Intern Med, 163, 2315, 10.1001/archinte.163.19.2315

Agency for Healthcare Research and Quality

Hodgson, 1999, Medical care expenditures for selected circulatory diseases: opportunities for reducing national health expenditures, Med Care, 37, 994, 10.1097/00005650-199910000-00004

Steinwachs, 2000, The future of cardiology: utilization and costs of care, J Am Coll Cardiol, 35, 91B, 10.1016/S0735-1097(00)80059-5