The Anti-Inflammatory Action of Griseofulvin in Experimental Animals

Journal of Pharmacy and Pharmacology - Tập 12 Số 1 - Trang 659-665 - 2011
P F D’Arcy1,2, Evelyn Howard1,2, P. W. Muggleton1,2, Shirley B Townsend1,2
1From Allen & Hanburys Limited, Ware, Hertfordshire
2Glaxo Laboratories Limited, Greenford, Middlesex

Tóm tắt

Abstract When tested by the cotton-pellet method in rats or the tuberculin-hypersensitivity test in guinea pigs, griseofulvin had a marked antiinflammatory action. The activity was, weight for weight, less than that of the corticosteroids tested concurrently. The anti-inflammatory action of griseofulvin appears to be independent of any effect upon the pituitary-adrenal axis.

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Tài liệu tham khảo

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Thông tin xuất bản

Journal of Pharmacy and Pharmacology

Tập 12 Số 1

659-665

Thông tin tác giả