The 2007 Rome Forum on the Treatment of Breast Cancer: first-line treatment choices for metastatic breast cancer in Europe

Giordano, 2004, Is breast cancer survival improving?, Cancer, 100, 44, 10.1002/cncr.11859 Gennari, 2005, Survival of metastatic breast carcinoma patients over a 20-year period: a retrospective analysis based on individual patient data from six consecutive studies, Cancer, 104, 1742, 10.1002/cncr.21359 Guarneri, 2004, The curability of breast cancer and the treatment of advanced disease, Eur J Nucl Med Mol Imaging, 31, S149, 10.1007/s00259-004-1538-5 Mackey, 2006, Trastuzumab prolongs progression-free survival in hormonedependent and HER2-positive metastatic breast cancer, Breast Cancer Res Treat, 100 Slamon, 2001, Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2, N Engl J Med, 344, 783, 10.1056/NEJM200103153441101 Marty, 2005, Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group, J Clin Oncol, 23, 4265, 10.1200/JCO.2005.04.173 Robert, 2006, Randomised phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer, J Clin Oncol, 24, 2786, 10.1200/JCO.2005.04.1764 Pegram, 2007, BCIRG 007: first overall survival analysis of randomised phase III trial of trastuzumab plus docetaxel with or without carboplatin as first line therapy in HER2 amplified metastatic breast cancer, J Clin Oncol, 25 Geyer, 2006, Lapatinib plus capecitabine for HER2-positive advanced breast cancer, N Engl J Med, 355, 2733, 10.1056/NEJMoa064320 Lin, 2007, EGF105084, a phase II study of lapatinib for brain metastases in patients (pts) with HER2+ breast cancer following trastuzumab (H) based systemic therapy and cranial radiotherapy (RT), J Clin Oncol, 25 Baselga, 2007, J Clin Oncol, 25 Gibson, 2007, Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women, Cochrane Database Syst Rev, CD003370 Vahdat, 2007, Phase III trial of ixabepilone plus capecitabine compared to capecitabine alone in patients with metastatic breast cancer (MBC) previously treated or resistant to an anthracycline and resistant to taxanes, J Clin Oncol, 25 Martín, 2007, Gemcitabine plus vinorelbine versus vinorelbine monotherapy in patients with metastatic breast cancer previously treated with anthracyclines and taxanes: final results of the phase III Spanish Breast Cancer Research Group (GEICAM) trial, Lancet Oncol, 8, 219, 10.1016/S1470-2045(07)70041-4 Gradishar, 2005, Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer, J Clin Oncol, 23, 7794, 10.1200/JCO.2005.04.937