Targeting to the hair follicles: Current status and potential

Prausnitz, 2004, Current status and future potential of transdermal drug delivery, Nat Rev Drug Discov, 3, 115, 10.1038/nrd1304

Mitragotri, 2006, Current status and future prospects of needle-free liquid jet injectors, Nat Rev Drug Discov, 5, 543, 10.1038/nrd2076

Karande, 2009, Enhancement of transdermal drug delivery via synergistic action of chemicals, Biochim Biophys Acta, 1788, 2362, 10.1016/j.bbamem.2009.08.015

Morrow, 2007, Innovative strategies for enhancing topical and transdermal drug delivery, Open Drug Deliv J, 1, 36, 10.2174/1874126600701010036

Cal, 2009, Across skin barrier: known methods, new performances, vol. 4, 162

Arora, 2008, Micro-scale devices for transdermal drug delivery, Int J Pharm, 364, 227, 10.1016/j.ijpharm.2008.08.032

Otberg, 2007, Follicular penetration of topically applied caffeine via a shampoo formulation, Skin Pharmacol Physiol, 20, 195, 10.1159/000101389

Lademann, 2008, Hair follicles – an efficient storage and penetration pathway for topically applied substances, Skin Pharmacol Physiol, 21, 150, 10.1159/000131079

Schaefer, 2001, The role of follicular penetration, Skin Pharmacol Physiol, 14, 23, 10.1159/000056386

Knorr, 2009, Follicular transport route – research progress and future perspectives, Eur J Pharm Biopharm, 71, 173, 10.1016/j.ejpb.2008.11.001

Vogt, 2007, Morphometry of human terminal and vellus hair follicles, Exp Dermatol, 16, 946, 10.1111/j.1600-0625.2007.00602.x

Tobin, 2006, Biochemistry of human skin – our brain on the outside, Chem Soc Rev, 35, 52, 10.1039/B505793K

Meidan, 2005, Transfollicular drug delivery – is it a reality?, Int J Pharm, 306, 1, 10.1016/j.ijpharm.2005.09.025

Patzelt, 2008, Hair follicles, their disorders and their opportunities, Drug Discov Today: Dis Mech, 5, 173, 10.1016/j.ddmec.2008.04.006

Krause, 2006, Biology of the hair follicle: the basics, Semin Cutan Med Surg, 25, 2, 10.1016/j.sder.2006.01.002

Kertesz, 2007, Ion beam microanalysis of human hair follicles, Nucl Instrum Methods Phys Res B, 260, 218, 10.1016/j.nimb.2007.02.025

Otberg, 2004, Variations of hair follicle size and distribution in different body sites, J Invest Dermatol, 122, 14, 10.1046/j.0022-202X.2003.22110.x

Lademann, 1999, Penetration of titanium dioxide microparticles in a sunscreen formulation into the horny layer and the follicular orifice, Skin Pharmacol Physiol, 12, 247, 10.1159/000066249

Knaggs, 2007, Cell biology of the pilosebaceous unit, 12

Ohyama, 2003, Gene delivery to the hair follicle, J Invest Dermatol Symp Proc, 8, 204, 10.1046/j.1087-0024.2003.00810.x

Hordinsky, 2008, Advances in hair diseases, Adv Dermatol, 24, 245, 10.1016/j.yadr.2008.09.013

Chase, 1969, The biology of hair growth, 3

MeidanVM, 2001, Treatments for androgenetic alopecia and alopecia areata. Current options and future prospects, Drugs, 61, 53, 10.2165/00003495-200161010-00006

Barry, 2002, Drug delivery routes in skin: a novel approach, Adv Drug Deliv Rev, 54, 31, 10.1016/S0169-409X(02)00113-8

Teichamann, 2006, Follicular penetration: development of a method to block the follicles selectively against the penetration of topically applied substances, Skin Pharmacol Physiol, 19, 216, 10.1159/000093117

Ossadnik, 2007, Differential stripping: introduction of a method to show the penetration of topically applied antifungal substances into the hair follicles, Mycoses, 50, 457, 10.1111/j.1439-0507.2007.01415.x

Lademann, 2006, Hair follicles – a long-term reservoir for drug delivery, Skin Pharmacol Physiol, 19, 232, 10.1159/000093119

Thielitz, 2001, Lipid analysis of follicular casts from cyanoacrylate strips as a new method for studying therapeutic effects of antiacne agents, Br J Dermatol, 145, 19, 10.1046/j.1365-2133.2001.04276.x

Grams, 2004, Time and depth resolved visualization of the diffusion of a lipophilic dye into the hair follicle of fresh unfixed human scalp skin, J Control Release, 98, 367, 10.1016/j.jconrel.2004.05.010

Lademann, 2001, Investigation of follicular penetration of topically applied substances, Skin Pharmacol Physiol, 14, 17, 10.1159/000056385

Toll, 2004, Penetration profile of microspheres in follicular targeting of terminal hair follicles, J Invest Dermatol, 123, 168, 10.1111/j.0022-202X.2004.22717.x

Shim, 2004, Transdermal delivery of minoxidil with block copolymer nanoparticles, J Control Release, 97, 477, 10.1016/j.jconrel.2004.03.028

Grice, 2010, Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro, J Pharm Sci, 99, 712, 10.1002/jps.21856

Ciotti, 2002, Follicular liposomal delivery systems, J Liposome Res, 12, 143, 10.1081/LPR-120004787

Tabbakhian, 2006, Enhancement of follicular delivery of finasteride by liposomes and niosomes. 1. In vitro permeation and in vivo deposition studies using hamster flank and ear models, Int J Pharm, 323, 1, 10.1016/j.ijpharm.2006.05.041

Frum, 2007, The influence of drug partition coefficient on follicular penetration: in vitro human skin studies, Eur J Pharm Sci, 30, 280, 10.1016/j.ejps.2006.11.014

Munster, 2005, RU 58841-myristate – prodrug development for topical treatment of acne and androgenetic alopecia, Pharmazie, 60, 8

Hueber, 1992, Role of transepidermal and transfollicular routes in percutaneous absorption of hydrocortisone and testosterone: in vivo study in the hairless rat, Skin Pharmacol, 5, 99, 10.1159/000211026

Teichmann, 2007, Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in a o/w microemulsion and an amphiphilic cream, Eur J Pharm Biopharm, 67, 699, 10.1016/j.ejpb.2007.04.006

Wu, 2001, Topical transport of hydrophilic compounds using water-in-oil nanoemulsions, Int J Pharm, 63, 63, 10.1016/S0378-5173(01)00671-8

Weiner, 1998, Targeted follicular delivery of macromolecules via liposomes, Int J Pharm, 162, 29, 10.1016/S0378-5173(97)00409-2

Mitragotri, 2003, Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways, J Control Release, 86, 69, 10.1016/S0168-3659(02)00321-8

Lekki, 2007, On the follicular pathway of percutaneous uptake of nanoparticles: ion microscopy and audioradiography studies, Nucl Instrum Methods Phys Res, 260, 174, 10.1016/j.nimb.2007.02.021

Zviak, 1986, Hair treatment and hair care products, 87

Vogt, 2006, 40nm, but not 750 or 1500nm, nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin, J Invest Dermatol, 126, 1316, 10.1038/sj.jid.5700226

Lademann, 2007, Nanoparticles – an efficient carrier for drug delivery into the hair follicles, Eur J Pharm Biopharm, 66, 159, 10.1016/j.ejpb.2006.10.019

Alvarez-Roman, 2004, Skin penetration and distribution of polymeric nanoparticles, J Control Release, 99, 53, 10.1016/j.jconrel.2004.06.015

Chen, 2006, Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting, J Control Release, 110, 296, 10.1016/j.jconrel.2005.09.052

Lingna, 1997, Topical liposome delivery of molecules to hair follicles in mice, J Dermatol Sci, 14, 101, 10.1016/S0923-1811(96)00557-9

Jung, 2006, Innovative liposomes as a transfollicular drug delivery system: penetration into porcine hair follicles, J Invest Dermatol, 126, 1728, 10.1038/sj.jid.5700323

Domashenko, 2000, Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex, Nat Biotechnol, 18, 420, 10.1038/74480

Hoffman, 2000, The hair follicles as a gene therapy target, Nat Biotechnol, 18, 20, 10.1038/71866

Li, 1995, The feasibility of targeted selective gene therapy of the hair follicle, Nat Med, 1, 705, 10.1038/nm0795-705

Zhao, 2000, A novel approach to gene therapy of albino hair in histoculture with a retroviral streptomyces tyrosinase gene, Pigment Cell Res, 13, 345, 10.1034/j.1600-0749.2000.130507.x

Grams, 2003, Permeant lipophilicity and vehicle composition influence accumulation of dyes in hair follicles of human skin, Eur J Pharm Sci, 18, 329, 10.1016/S0928-0987(03)00035-6

Ossadnik, 2006, Investigation of differences in follicular penetration of particle- and nonparticle-containing emulsions by laser scanning microscopy, Laser Phys, 16, 747, 10.1134/S1054660X06050033

Illel, 1997, Formulation for transfollicular drug administration: some recent advances, Crit Rev Ther Drug Carrier Syst, 14, 207, 10.1615/CritRevTherDrugCarrierSyst.v14.i3.10