T cell costimulation blockade promotes transplantation tolerance in combination with sirolimus and post-transplantation cyclophosphamide for haploidentical transplantation in children with severe aplastic anemia
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Georges, 2016, Hematopoietic stem cell transplantation for acquired aplastic anemia, Curr.Opin.Hematol., 23, 495, 10.1097/MOH.0000000000000281
Clay, 2014, Nonmyeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia, Biol. Blood Marrow Transplant., 20, 1711, 10.1016/j.bbmt.2014.06.028
Esteves, 2015, Haploidentical BMT and post-transplant Cy for severe aplastic anemia: a multicenter retrospective study, Bone Marrow Transplant., 50, 685, 10.1038/bmt.2015.20
Jaiswal, 2015, Pre-transplant sirolimus might improve the outcome of haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide for patients with severe aplastic anemia, Bone Marrow Transplant., 50, 873, 10.1038/bmt.2015.50
Jaiswal, 2015, Hemophagocytic syndrome following haploidentical peripheral blood stem cell transplantation with post-transplant cyclophosphamide, Int. J. Hematol., 103, 234, 10.1007/s12185-015-1905-y
Jaiswal, 2016, Haploidentical transplantation in children with unmanipulated peripheral blood stem cell graft: The need to look beyond post-transplantation cyclophosphamide in younger children, Pediatr. Transplant., 20, 675, 10.1111/petr.12724
Blazar, 1994, In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice, Blood, 83, 3815, 10.1182/blood.V83.12.3815.3815
Guinan, 1999, Transplantation of anergic histoincompatible bone marrow allografts, N. Engl. J. Med., 340, 1704, 10.1056/NEJM199906033402202
Koura, 2013, In vivo T cell costimulation blockade with abatacept for acute graft-versus-host disease prevention: a first-in-disease trial, Biol. Blood Marrow Transplant., 19, 1638, 10.1016/j.bbmt.2013.09.003
Jaiswal, 2016, T cell costimulation blockade for hyperacute steroid refractory graft versus-host disease in children undergoing haploidentical transplantation, Transpl. Immunol., 39, 46, 10.1016/j.trim.2016.08.009
de Graav, 2016, Down-regulation of surface CD28 under belatacept treatment: an escape mechanism for antigen-reactive T-cells, PLoS One, 11, 10.1371/journal.pone.0148604
Kanakry, 2013, Aldehyde dehydrogenase expression drives human regulatory T cell resistance to posttransplantation cyclophosphamide, Sci. Transl. Med., 5, 211ra157, 10.1126/scitranslmed.3006960
Lo, 2013, Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion, Am. J. Transplant., 13, 320, 10.1111/j.1600-6143.2012.04342.x
Pilat, 2011, Costimulatory pathways in transplantation, Semin. Immunol., 23, 293, 10.1016/j.smim.2011.04.002
Snanoudj, 2006, Costimulation blockade and its possible future use in clinical transplantation, Transpl. Int., 19, 693, 10.1111/j.1432-2277.2006.00332.x
Yamada, 2002, The CD154-CD40 costimulatory pathway in transplantation, Transplantation, 73, S36, 10.1097/00007890-200201151-00012
Storb, 1999, Stable mixed hematopoietic chimerism in dogs given donor antigen, CTLA4Ig, and 100 cGy total body irradiation before and pharmacologic immunosuppression after marrow transplant, Blood, 94, 2523, 10.1182/blood.V94.7.2523.419k18_2523_2529
Jonker, 2002, Blocking the CD80 and CD86 costimulation molecules: lessons to be learned from animal models, Transplantation, 73, S23, 10.1097/00007890-200201151-00009
Wekerle, 2000, Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment, Nat. Med., 6, 464, 10.1038/74731
Luznik, 2010, High-dose cyclophosphamide for graft-versus-host disease prevention, Curr. Opin. Hematol., 17, 493, 10.1097/MOH.0b013e32833eaf1b
Schuurhuis, 2006, Ins and outs of dendritic cells, Int. Arch. Allergy Immunol., 140, 53, 10.1159/000092002
Bonfim, 2017, Haploidentical bone marrow transplantation with post-transplant cyclophosphamide for children and adolescents with Fanconi anemia, Biol. Blood Marrow Transplant., 23, 310, 10.1016/j.bbmt.2016.11.006
Kitchens, 2012, Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells, Am. J. Transplant., 12, 69, 10.1111/j.1600-6143.2011.03762.x
Ramsey, 2013, Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients, Transpl. Int., 26, 206, 10.1111/tri.12021
Davies, 2015, Donor-derived T cells can be rendered hyporesponsive to alloantigen without loss of pathogen or tumor immune responses, Blood, 110, 771, 10.1182/blood.V110.11.771.771
Pinelli, 2015, Rapamycin ameliorates the CTLA4-Ig-mediated defect in CD8(+) T cell immunity during gammaherpesvirus infection, Am. J. Transplant., 15, 2576, 10.1111/ajt.13326
Povoleri, 2013, Thymic versus induced regulatory T cells - who regulates the regulators?, Front. Immunol., 4, 169, 10.3389/fimmu.2013.00169
Riella, 2012, Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model, Am. J. Transplant., 12, 846, 10.1111/j.1600-6143.2011.03929.x
Bestard, 2011, Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation, Transpl. Int., 24, 451, 10.1111/j.1432-2277.2011.01223.x
Pilat, 2015, Rapamycin and CTLA4Ig synergize to induce stable mixed chimerism without the need for CD40 blockade, Am. J. Transplant., 15, 1568, 10.1111/ajt.13154
Grohmann, 2002, CTLA-4-Ig regulates tryptophan catabolism in vivo, Nat. Immunol., 3, 1097, 10.1038/ni846