T-cell-biased immune responses generated by a mucosally targeted adenovirus-σ1 vaccine

Mucosal Immunology - Tập 5 - Trang 311-319 - 2012
E A Weaver1, G T Mercier2, S Gottschalk3, M A Barry1,4,5
1Department of Internal Medicine, Division of Infectious Diseases, Translational Immunovirology and Biodefense Program, Mayo Clinic, Rochester, Minnesota, USA
2Department of Physics, University of Houston, Houston, Texas, USA
3Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA
4Department of Immunology, Mayo Clinic, Rochester, Minnesota USA
5Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota, USA

Tài liệu tham khảo

Lehner, 2002, Mucosal immunity and vaccination against HIV, AIDS, 16, S125, 10.1097/00002030-200216004-00017 Simecka, 1998, Mucosal immunity of the gastrointestinal tract and oral tolerance, Adv. Drug Deliv. Rev, 34,, 235, 10.1016/S0169-409X(98)00042-8 Kaneko, 2000, Oral DNA vaccination promotes mucosal and systemic immune responses to HIV envelope glycoprotein, Virology, 267,, 8, 10.1006/viro.1999.0093 Bergelson, 1997, Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5, Science (New York, NY), 275,, 1320, 10.1126/science.275.5304.1320 Wickham, 1993, Integrins avb3 or avb5 promote adenovirus internalization but not virus attachment, Cell, 73,, 309, 10.1016/0092-8674(93)90231-E Zabner, 1997, Lack of high affinity fiber receptor activity explains the resistance of ciliated airway epithelia to adenovirus infection, J. Clin. Invest, 100,, 1144, 10.1172/JCI119625 Grubb, 1994, Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans, Nature, 371,, 802, 10.1038/371802a0 Mercier, 2004, A chimeric adenovirus vector encoding reovirus attachment protein sigma1 targets cells expressing junctional adhesion molecule 1, Proc. Natl. Acad. Sci. USA, 101,, 6188, 10.1073/pnas.0400542101 Chappell, 1997, Mutations in type 3 reovirus that determine binding to sialic acid are contained in the fibrous tail domain of viral attachment protein sigma1, J. Virol, 71,, 1834, 10.1128/jvi.71.3.1834-1841.1997 Forrest, 2003, Structure-function analysis of reovirus binding to junctional adhesion molecule 1: implications for the mechanism of reovirus attachment, J. Biol. Chem, 278,, 48434, 10.1074/jbc.M305649200 Von Seggern, 2000, Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein–Barr virus-transformed B cells, J. Virol, 74,, 354, 10.1128/JVI.74.1.354-362.2000 Campos, 2004, Rapid construction of capsid-modified adenoviral vectors through bacteriophage lambda red recombination, Hum. Gene Ther, 15,, 1125, 10.1089/hum.2004.15.1125 Mok, 2005, Evaluation of polyethylene glycol modification of first-generation and helper-dependent adenoviral vectors to reduce innate immune responses, Mol. Ther, 11,, 66, 10.1016/j.ymthe.2004.09.015 Hofherr, 2008, Modification of adenoviral vectors with polyethylene glycol modulates in vivo tissue tropism and gene expression, Mol. Ther, 16,, 1276, 10.1038/mt.2008.86 Mercier, 2007, Oral immunization of rhesus macaques with adenoviral HIV vaccines using enteric-coated capsules, Vaccine, 25,, 8687, 10.1016/j.vaccine.2007.10.030 Gottschalk, 2003, Generating CTLs against the subdominant Epstein–Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies, Blood, 101,, 1905, 10.1182/blood-2002-05-1514 Leen, 2004, Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications, Blood, 103,, 1011, 10.1182/blood-2003-07-2449