H. C. Beyerman1, B. S. L. Bordes1, L. Maat1, Frans Warnaar1
1Laboratory of Organic Chemistry, Technische Hogeschool, Julianalaan 136, Delft The Netherlands
Tóm tắt
AbstractThe four isomers of N‐methylsedridine {2‐(2‐hydroxypropyl)‐1‐methylpiperidine} were prepared in different ways. The absolute configurations were determined using both optical rotatory dispersion and chemical correlation. The alkaloid occurring in Sedum sarmentosum Bunge is (+)‐(2R)‐2‐{(2S)‐2‐hydroxypropyl)}‐1‐methylpiperidine, (+)‐N‐methylallosedridine (IIIa).
