Synthesis of neuropeptide Y*

Wiley - Tập 29 Số 1 - Trang 78-83 - 1987
A. Balasubramaniam1, Ingrid L. Grupp1, Laxmi S. Srivastava1, Kazuhiko Tatemoto2, Richard F. Murphy1, Stephen N. Joffe1, Josef E. Fischer1
1Departments of Surgery, Internal Medicine, Physiology and Pharmacology and Cell Biophysics, University of Cincinnati Medical Center, Cincinnati, Ohio
2Department of Psychiatry, Stanford Univeristy Medical Center, Stanford, California, USA

Tóm tắt

Neuropeptide Y (NPY), a hexatriacontapeptide amide, was synthesized on benzhydrylamine resin. The peptide product obtained by HF treatment contained 63% of the target peptide, NPY. A comparison of the chemical, immuno‐chemical and biological properties of the synthetic peptide with natural NPY indicated that they were identical.

Từ khóa


Tài liệu tham khảo

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Wiley

Tập 29 Số 1

78-83

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